Drug Transporter (DT) Information

General Information of DT
DT ID DTD0300
Gene Name SLC35D3
Protein Name Fringe connection-like protein 1
Gene ID
340146
UniProt ID
Q5M8T2
TCDB ID
2.A.7.15.5
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms FRCL1; SLC35D3; Solute carrier family 35 member D3
DT Family Drug/Metabolite Transporter (DMT) Superfamily
UDP-glucuronate/UDP-N-acetylgalactosamine Transporter (UGnT) Family
Function This transporter can be used as a regulator for biosynthesis of platelet-dense particles and plays a role in hemostasis.
Endogenous Substrate(s) UDP-sugar
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Fringe connection-like protein 1
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Fringe connection-like protein 1
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Fringe connection-like protein 1
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Fringe connection-like protein 1
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Fringe connection-like protein 1
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Fringe connection-like protein 1
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Fringe connection-like protein 1
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Fringe connection-like protein 1
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Fringe connection-like protein 1
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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