Modelled DT Structure
Method: multi-sequence alignment based machine learning
Detail: Structure Info
Drug Transporter (DT) Information
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| General Information of DT | |||||
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| DT ID | DTD0354 | ||||
| Gene Name | SLC41A1 | ||||
| Protein Name | Magnesium transporter protein solute carrier family 41 member 1 | ||||
| Gene ID | |||||
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| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method: multi-sequence alignment based machine learning Detail: Structure Info |
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| Synonyms | MgtE; SLC41A1; Solute carrier family 41 member 1 | ||||
| DT Family | Mg(2+) Transporter-E (MGTE) Family ; | ||||
| Tissue Specificity | Highest expression levels in heart and testis,slightly less in skeletal muscles, prostate, adrenal gland andthyroid, and weakest in the hematopoietic tissues bones marrow,lymph node, thymus and spleen. | ||||
| Function | This tranaporter mediates the transport of magnesium and is responsive to magnesium balance. | ||||
| Endogenous Substrate(s) | Mg2+ | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Magnesium transporter protein solute carrier family 41 member 1 |
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(β) Cell Distribution Level of Magnesium transporter protein solute carrier family 41 member 1 |
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(γ) Organelle Distribution Level of Magnesium transporter protein solute carrier family 41 member 1 |
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Regulatory Variability Data of This DT |
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(α) Microbiota Influence of Magnesium transporter protein solute carrier family 41 member 1 |
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(β) Post-translational Modification of Magnesium transporter protein solute carrier family 41 member 1 |
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(γ) Transcriptional Regulation of Magnesium transporter protein solute carrier family 41 member 1 |
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(δ) Epigenetic Regulation of Magnesium transporter protein solute carrier family 41 member 1 |
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(ε) Exogenous Modulation of Magnesium transporter protein solute carrier family 41 member 1 |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Magnesium transporter protein solute carrier family 41 member 1 |
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(β) Disease-specific Protein Abundances of Magnesium transporter protein solute carrier family 41 member 1 |
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(γ) Species- and Tissue-specific DT Abundances |
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If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.