| General Information of DT | |||||
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| DT ID | DTD0289 | ||||
| Gene Name | SLC35A3 | ||||
| Protein Name | UDP-N-acetylglucosamine transporter | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:6OH4_A Identity:42.444% Minimized Score:-856.243 kcal/mol Detail: Structure Info |
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| Synonyms | AMRS; Golgi UDP-GlcNAc transporter; SLC35A3; Solute carrier family 35 member A3 | ||||
| DT Family | Drug/Metabolite Transporter (DMT) Superfamily | ||||
| CMP-Sialate:CMP Antiporter (CSA) Family | |||||
| Function | This transporter is uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. It may supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides. | ||||
| Endogenous Substrate(s) | UDP-N-acetylglucosamine | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of UDP-N-acetylglucosamine transporter |
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(β) Cell Distribution Level of UDP-N-acetylglucosamine transporter |
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(γ) Organelle Distribution Level of UDP-N-acetylglucosamine transporter |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of UDP-N-acetylglucosamine transporter |
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(γ) Transcriptional Regulation of UDP-N-acetylglucosamine transporter |
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(δ) Epigenetic Regulation of UDP-N-acetylglucosamine transporter |
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(ε) Exogenous Modulation of UDP-N-acetylglucosamine transporter |
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Structural Variability Data of This DT |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of UDP-N-acetylglucosamine transporter |
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(β) Disease-specific Protein Abundances of UDP-N-acetylglucosamine transporter |
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(γ) Species- and Tissue-specific DT Abundances |
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