Detail Information of Transcriptional Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0240 Transporter Info
Gene Name	SLC27A3
Transporter Name	Long-chain fatty acid transport protein 3
Gene ID	11000
UniProt ID	Q5K4L6

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains
Class1.1: Basic leucine zipper factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
CEBPB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	CCAAT/enhancer-binding protein beta		Transcription Factor Info
Tissue	Blood; Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein beta (CEBPB) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
CEBPD		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	CCAAT/enhancer-binding protein delta		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein delta (CEBPD) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class1.2: Basic helix-loop-helix factors		Click to Show/Hide the Full List of 5 TF(s) Regulating This DT
MAX		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Protein max		Transcription Factor Info
Tissue	Blood; Bone marrow; Brain; Breast; Embryo; Liver; Uterus; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Protein max (MAX) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
MITF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC27A3 gene in melanoma condition			[4]
TF Protein Name	Microphthalmia-associated transcription factor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of SLC27A3 gene in melanoma condition, which leads to an increased expression of the drug transporter Long-chain fatty acid transport protein 3.
MXI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Max-interacting protein 1		Transcription Factor Info
Tissue	Cervix
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Max-interacting protein 1 (MXI1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TCF3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Transcription factor E2-alpha		Transcription Factor Info
Tissue	Blood; Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2-alpha (TCF3) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TFAP4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Transcription factor AP-4		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-4 (TFAP4) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class1.3: Basic helix-span-helix factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TFAP2C		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Transcription factor AP-2 gamma		Transcription Factor Info
Tissue	Breast; Cervix; Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass2: Zinc-coordinating DNA-binding domains
Class2.1: Nuclear receptors with C4 zinc fingers		Click to Show/Hide the Full List of 4 TF(s) Regulating This DT
AR		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC27A3 gene in prostate cancer condition			[6]
TF Protein Name	Androgen receptor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Androgen receptor (AR) has been reported to bind to the transcription of SLC27A3 gene in prostate cancer condition, which leads to an affected expression of the drug transporter Long-chain fatty acid transport protein 3.
HNF4G		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Hepatocyte nuclear factor 4-gamma		Transcription Factor Info
Tissue	Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hepatocyte nuclear factor 4-gamma (HNF4G) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
NR2F2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	COUP transcription factor 2		Transcription Factor Info
Tissue	Bone marrow; Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	COUP transcription factor 2 (NR2F2) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
PPARD		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC27A3 gene in myofibroblasts condition			[7]
TF Protein Name	Peroxisome proliferator-activated receptor delta		Transcription Factor Info
Related DT Changes	Up regulating
Detailed Description	Peroxisome proliferator-activated receptor delta (PPARD) has been reported to activate the transcription of SLC27A3 gene in myofibroblasts condition, which leads to an increased expression of the drug transporter Long-chain fatty acid transport protein 3.
Class2.2: Other C4 zinc finger-type factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
GATA2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC27A3 gene in megakaryocytes condition			[8]
TF Protein Name	Endothelial transcription factor GATA-2		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Endothelial transcription factor GATA-2 (GATA2) has been reported to bind to the transcription of SLC27A3 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Long-chain fatty acid transport protein 3.
Class2.3: C2H2 zinc finger factors		Click to Show/Hide the Full List of 12 TF(s) Regulating This DT
BCL6		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	B-cell lymphoma 6 protein		Transcription Factor Info
Tissue	Tonsil
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	B-cell lymphoma 6 protein (BCL6) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
CTCF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Transcriptional repressor CTCF		Transcription Factor Info
Tissue	Brain
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor CTCF (CTCF) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
EGR1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Early growth response protein 1		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Early growth response protein 1 (EGR1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
KLF4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Krueppel-like factor 4		Transcription Factor Info
Tissue	Breast; Pancreatic ductal; Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 4 (KLF4) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
KLF5		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Krueppel-like factor 5		Transcription Factor Info
Tissue	Colon; Pancreatic ductal; Stomach
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 5 (KLF5) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
KLF9		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Krueppel-like factor 9		Transcription Factor Info
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 9 (KLF9) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
MAZ		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Myc-associated zinc finger protein		Transcription Factor Info
Tissue	Blood; Bone marrow; Cervix; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Myc-associated zinc finger protein (MAZ) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
SP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Transcription factor Sp1		Transcription Factor Info
Tissue	Blood; Colon; Embryo; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor Sp1 (SP1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
SP4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Transcription factor Sp4		Transcription Factor Info
Tissue	Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor Sp4 (SP4) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
YY1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Transcriptional repressor protein YY1		Transcription Factor Info
Tissue	Blood; Bone marrow; Embryo; Liver; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor protein YY1 (YY1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
ZBTB7A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Zinc finger and BTB domain-containing protein 7A		Transcription Factor Info
Tissue	Bone marrow; Liver; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger and BTB domain-containing protein 7A (ZBTB7A) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
ZNF263		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Zinc finger protein 263		Transcription Factor Info
Tissue	Kidney
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger protein 263 (ZNF263) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass3: Helix-turn-helix domains
Class3.1: Homeo domain factors		Click to Show/Hide the Full List of 3 TF(s) Regulating This DT
PBX1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Pre-B-cell leukemia transcription factor 1		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Pre-B-cell leukemia transcription factor 1 (PBX1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
POU2F1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	POU domain, class 2, transcription factor 1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	POU domain, class 2, transcription factor 1 (POU2F1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
ZEB1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Zinc finger E-box-binding homeobox 1		Transcription Factor Info
Tissue	Blood; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger E-box-binding homeobox 1 (ZEB1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class3.2: Paired box factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
PAX5		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Paired box protein Pax-5		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Paired box protein Pax-5 (PAX5) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class3.3: Fork head / winged helix factors		Click to Show/Hide the Full List of 5 TF(s) Regulating This DT
E2F3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Transcription factor E2F3		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F3 (E2F3) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
E2F4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC27A3 gene in health condition			[9]
TF Protein Name	Transcription factor E2F4		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC27A3 gene in health condition, which leads to an affected expression of the drug transporter Long-chain fatty acid transport protein 3.
E2F6		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Transcription factor E2F6		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F6 (E2F6) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
E2F7		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Transcription factor E2F7		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F7 (E2F7) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
FOXP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Forkhead box protein P1		Transcription Factor Info
Tissue	Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Forkhead box protein P1 (FOXP1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class3.5: Tryptophan cluster factors		Click to Show/Hide the Full List of 10 TF(s) Regulating This DT
ELF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	ETS-related transcription factor Elf-1		Transcription Factor Info
Tissue	Blood; Bone marrow; Breast; Liver; Mesenchymal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	ETS-related transcription factor Elf-1 (ELF1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
ELK3		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC27A3 gene in hypoxia condition			[10]
TF Protein Name	ETS domain-containing protein Elk-3		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	ETS domain-containing protein Elk-3 (ELK3) has been reported to bind to the transcription of SLC27A3 gene in hypoxia condition, which leads to an affected expression of the drug transporter Long-chain fatty acid transport protein 3.
Transcriptional Phenomenon2	Direct binding to SLC27A3 gene			[5]
TF Protein Name	ETS domain-containing protein Elk-3		Transcription Factor Info
Tissue	Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	ETS domain-containing protein Elk-3 (ELK3) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
ERG		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC27A3 gene in leukemia condition			[11]
TF Protein Name	Transcriptional regulator ERG		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Transcriptional regulator ERG (ERG) has been reported to activate the transcription of SLC27A3 gene in leukemia condition, which leads to an increased expression of the drug transporter Long-chain fatty acid transport protein 3.
Transcriptional Phenomenon2	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Transcriptional regulator ERG		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional regulator ERG (ERG) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
ETV1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	ETS translocation variant 1		Transcription Factor Info
Tissue	GastroIntestine tract; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	ETS translocation variant 1 (ETV1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
FLI1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC27A3 gene in megakaryocytes condition			[8]
TF Protein Name	Friend leukemia integration 1 transcription factor		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Friend leukemia integration 1 transcription factor (FLI1) has been reported to bind to the transcription of SLC27A3 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Long-chain fatty acid transport protein 3.
Transcriptional Phenomenon2	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Friend leukemia integration 1 transcription factor		Transcription Factor Info
Tissue	Blood; Mesenchymal; Umbilical cord blood; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
GABPA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	GA-binding protein alpha chain		Transcription Factor Info
Tissue	Blood; Bone marrow; Breast; Cervix; Liver; Mesenchymal; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	GA-binding protein alpha chain (GABPA) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
IRF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Interferon regulatory factor 1		Transcription Factor Info
Tissue	Blood; Pancreatic ductal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Interferon regulatory factor 1 (IRF1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
IRF4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Interferon regulatory factor 4		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Interferon regulatory factor 4 (IRF4) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
MYB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Transcriptional activator Myb		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional activator Myb (MYB) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
SPI1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC27A3 gene in acute myeloid leukemia condition			[12]
TF Protein Name	Transcription factor PU.1		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor PU.1 (SPI1) has been reported to bind to the transcription of SLC27A3 gene in acute myeloid leukemia condition, which leads to an affected expression of the drug transporter Long-chain fatty acid transport protein 3.
Transcriptional Phenomenon2	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Transcription factor PU.1		Transcription Factor Info
Tissue	Adrenal gland; Blood; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor PU.1 (SPI1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class3.7: ARID domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
KDM5B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Lysine-specific demethylase 5B		Transcription Factor Info
Tissue	Bone marrow; Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass5: alpha-Helices exposed by beta-structures
Class5.3: SAND domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
GMEB2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Glucocorticoid modulatory element-binding protein 2		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Glucocorticoid modulatory element-binding protein 2 (GMEB2) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass6: Immunoglobulin fold
Class6.1: Rel homology region factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
EBF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[1]
TF Protein Name	Transcription factor COE1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor COE1 (EBF1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class6.3: p53 domain factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
TP63		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Tumor protein 63		Transcription Factor Info
Tissue	Epithelium; Thyroid
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Tumor protein 63 (TP63) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TP73		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Tumor protein p73		Transcription Factor Info
Tissue	Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Tumor protein p73 (TP73) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
Class6.4: Runt domain factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
RUNX2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[2]
TF Protein Name	Runt-related transcription factor 2		Transcription Factor Info
Tissue	Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Runt-related transcription factor 2 (RUNX2) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
RUNX3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Runt-related transcription factor 3		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Runt-related transcription factor 3 (RUNX3) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold
Class7.1: SMAD/NF-1 DNA-binding domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
NFIC		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	Nuclear factor 1 C-type		Transcription Factor Info
Tissue	Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Nuclear factor 1 C-type (NFIC) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass8: beta-Sheet binding to DNA
Class8.1: TATA-binding proteins		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TBP		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[3]
TF Protein Name	TATA-box-binding protein		Transcription Factor Info
Tissue	Cervix; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	TATA-box-binding protein (TBP) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.
TF Superclass10: Yet undefined DNA-binding domains
Class10: Uncharacterized		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
NRF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC27A3 gene			[5]
TF Protein Name	Nuclear respiratory factor 1		Transcription Factor Info
Tissue	Brain; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Nuclear respiratory factor 1 (NRF1) can directly bind to the SLC27A3 gene, which in turn affects the expression or function of the drug transporter Long-chain fatty acid transport protein 3.

References
1	Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
2	The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
3	hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-306. (ID:ENSG00000143554)
4	Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
5	NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
6	Integrated expression profiling and ChIP-seq analyses of the growth inhibition response program of the androgen receptor. PLoS One. 2009;4(8):e6589.
7	Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor. PLoS One. 2011;6(1):e16344.
8	Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
9	Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res. 2011;39(9):3558-73.
10	The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. PLoS One. 2014;9(11):e113050.
11	Genome-wide screen reveals WNT11, a non-canonical WNT gene, as a direct target of ETS transcription factor ERG. Oncogene. 2011;30(17):2044-56.
12	Structurally differentiated cis-elements that interact with PU.1 are functionally distinguishable in acute promyelocytic leukemia. J Hematol Oncol. 2013;6:25.

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