Detail Information of Transcriptional Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0227 Transporter Info
Gene Name	SLC26A1
Transporter Name	Sulfate anion transporter 1
Gene ID	10861
UniProt ID	Q9H2B4

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains
Class1.1: Basic leucine zipper factors		Click to Show/Hide the Full List of 9 TF(s) Regulating This DT
ATF3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Cyclic AMP-dependent transcription factor ATF-3		Transcription Factor Info
Tissue	Bone marrow; Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Cyclic AMP-dependent transcription factor ATF-3 (ATF3) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
BACH1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC26A1 gene in breast cancer bone metastasis condition			[2]
TF Protein Name	Transcription regulator protein BACH1		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Transcription regulator protein BACH1 (BACH1) has been reported to activate the transcription of SLC26A1 gene in breast cancer bone metastasis condition, which leads to an increased expression of the drug transporter Sulfate anion transporter 1.
BACH2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Transcription regulator protein BACH2		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription regulator protein BACH2 (BACH2) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
CEBPB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	CCAAT/enhancer-binding protein beta		Transcription Factor Info
Tissue	Bone
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein beta (CEBPB) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
CEBPD		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	CCAAT/enhancer-binding protein delta		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein delta (CEBPD) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
CREB1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Cyclic AMP-responsive element-binding protein 1		Transcription Factor Info
Tissue	Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
FOSL2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Fos-related antigen 2		Transcription Factor Info
Tissue	Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Fos-related antigen 2 (FOSL2) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
JUN		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC26A1 gene in K562 cells			[6]
TF Protein Name	Transcription factor Jun		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Transcription factor Jun (JUN) has been reported to bind to the transcription of SLC26A1 gene in K562 cells, which leads to an affected expression of the drug transporter Sulfate anion transporter 1.
NFE2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Transcription factor NF-E2 45 kDa subunit		Transcription Factor Info
Tissue	Bone marrow; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor NF-E2 45 kDa subunit (NFE2) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class1.2: Basic helix-loop-helix factors		Click to Show/Hide the Full List of 6 TF(s) Regulating This DT
ARNT		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Aryl hydrocarbon receptor nuclear translocator		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Aryl hydrocarbon receptor nuclear translocator (ARNT) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
BHLHE40		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Class E basic helix-loop-helix protein 40		Transcription Factor Info
Tissue	Bone marrow; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Class E basic helix-loop-helix protein 40 (BHLHE40) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
MITF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC26A1 gene in melanoma condition			[7]
TF Protein Name	Microphthalmia-associated transcription factor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of SLC26A1 gene in melanoma condition, which leads to an increased expression of the drug transporter Sulfate anion transporter 1.
MYOD1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Myoblast determination protein 1		Transcription Factor Info
Tissue	Myotube
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Myoblast determination protein 1 (MYOD1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TCF12		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Transcription factor 12		Transcription Factor Info
Tissue	Blood; Breast; Liver; Lung; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor 12 (TCF12) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TCF3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Transcription factor E2-alpha		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2-alpha (TCF3) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class1.3: Basic helix-span-helix factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
TFAP2A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Transcription factor AP-2-alpha		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-2-alpha (TFAP2A) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TFAP2C		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Transcription factor AP-2 gamma		Transcription Factor Info
Tissue	Breast; Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TF Superclass2: Zinc-coordinating DNA-binding domains
Class2.1: Nuclear receptors with C4 zinc fingers		Click to Show/Hide the Full List of 5 TF(s) Regulating This DT
AR		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC26A1 gene in prostate cancer condition			[8]
TF Protein Name	Androgen receptor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Androgen receptor (AR) has been reported to bind to the transcription of SLC26A1 gene in prostate cancer condition, which leads to an affected expression of the drug transporter Sulfate anion transporter 1.
ESR1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Estrogen receptor		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Estrogen receptor (ESR1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
HNF4A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC26A1 gene in health condition			[9]
TF Protein Name	Hepatocyte nuclear factor 4-alpha		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of SLC26A1 gene in health condition, which leads to an affected expression of the drug transporter Sulfate anion transporter 1.
NR2F2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	COUP transcription factor 2		Transcription Factor Info
Tissue	Bone marrow; Breast; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	COUP transcription factor 2 (NR2F2) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
PGR		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Progesterone receptor		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Progesterone receptor (PGR) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class2.2: Other C4 zinc finger-type factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
GATA1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Erythroid transcription factor		Transcription Factor Info
Tissue	Blood; Bone marrow; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Erythroid transcription factor (GATA1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class2.3: C2H2 zinc finger factors		Click to Show/Hide the Full List of 11 TF(s) Regulating This DT
CTCF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Transcriptional repressor CTCF		Transcription Factor Info
Tissue	Brain
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor CTCF (CTCF) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
EGR1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC26A1 gene in erythroleukemia condition			[10]
TF Protein Name	Early growth response protein 1		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Early growth response protein 1 (EGR1) has been reported to bind to the transcription of SLC26A1 gene in erythroleukemia condition, which leads to an affected expression of the drug transporter Sulfate anion transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Early growth response protein 1		Transcription Factor Info
Tissue	Blood; Bone marrow; Breast; Colon; Embryo; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Early growth response protein 1 (EGR1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
KLF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Krueppel-like factor 1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 1 (KLF1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
KLF4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Krueppel-like factor 4		Transcription Factor Info
Tissue	Breast; Pancreatic ductal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 4 (KLF4) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
KLF5		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Krueppel-like factor 5		Transcription Factor Info
Tissue	Colon; Pancreatic ductal; Stomach
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 5 (KLF5) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
KLF9		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Krueppel-like factor 9		Transcription Factor Info
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 9 (KLF9) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
MAZ		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Myc-associated zinc finger protein		Transcription Factor Info
Tissue	Blood; Bone marrow; Cervix; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Myc-associated zinc finger protein (MAZ) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
SP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Transcription factor Sp1		Transcription Factor Info
Tissue	Blood; Colon; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor Sp1 (SP1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
YY1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Transcriptional repressor protein YY1		Transcription Factor Info
Tissue	Blood; Bone marrow; Colon; Liver; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor protein YY1 (YY1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
ZBTB7A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Zinc finger and BTB domain-containing protein 7A		Transcription Factor Info
Tissue	Bone marrow; Liver; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger and BTB domain-containing protein 7A (ZBTB7A) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
ZNF263		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Zinc finger protein 263		Transcription Factor Info
Tissue	Bone marrow; Kidney
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger protein 263 (ZNF263) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TF Superclass3: Helix-turn-helix domains
Class3.1: Homeo domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
HNF1B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC26A1 gene in renal cysts condition			[11]
TF Protein Name	Hepatocyte nuclear factor 1-beta		Transcription Factor Info
Studied Phenotype	Renal cysts [ICD11: GB80]
Tissue	Kidney
Related DT Changes	Up regulating
Experimental Material	Zebrafish TgPT::EGFP)
Detailed Description	Hepatocyte nuclear factor 1-beta (HNF1B) has been reported to activate the transcription of SLC26A1 gene in renal cysts condition, which leads to an increased expression of the drug transporter Sulfate anion transporter 1.
Class3.3: Fork head / winged helix factors		Click to Show/Hide the Full List of 4 TF(s) Regulating This DT
E2F1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Transcription factor E2F1		Transcription Factor Info
Tissue	Mesenchymal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F1 (E2F1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
E2F6		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Transcription factor E2F6		Transcription Factor Info
Tissue	Bone marrow; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F6 (E2F6) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
FOXA1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Hepatocyte nuclear factor 3-alpha		Transcription Factor Info
Tissue	Breast; Liver; Lung; Pancreatic ductal; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
FOXP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Forkhead box protein P1		Transcription Factor Info
Tissue	Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Forkhead box protein P1 (FOXP1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class3.5: Tryptophan cluster factors		Click to Show/Hide the Full List of 5 TF(s) Regulating This DT
ETS1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Protein C-ets-1		Transcription Factor Info
Tissue	Blood; Bone; Bone marrow; Kidney
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Protein C-ets-1 (ETS1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
FLI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Friend leukemia integration 1 transcription factor		Transcription Factor Info
Tissue	Blood; Mesenchymal; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
GABPA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	GA-binding protein alpha chain		Transcription Factor Info
Tissue	Bone marrow; Breast; Cervix; Embryo; Liver; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	GA-binding protein alpha chain (GABPA) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
IRF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Interferon regulatory factor 1		Transcription Factor Info
Tissue	Bone marrow; Pancreatic ductal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Interferon regulatory factor 1 (IRF1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
SPI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[4]
TF Protein Name	Transcription factor PU.1		Transcription Factor Info
Tissue	Adrenal gland; Blood; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor PU.1 (SPI1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class3.6: TEA domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TEAD4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Transcriptional enhancer factor TEF-3		Transcription Factor Info
Tissue	Bone marrow; Embryo; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional enhancer factor TEF-3 (TEAD4) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class3.7: ARID domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
KDM5B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Lysine-specific demethylase 5B		Transcription Factor Info
Tissue	Bone marrow; Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TF Superclass6: Immunoglobulin fold
Class6.1: Rel homology region factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
EBF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[3]
TF Protein Name	Transcription factor COE1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor COE1 (EBF1) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
Class6.3: p53 domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TP63		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC26A1 gene in health condition			[12]
TF Protein Name	Tumor protein 63		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Tumor protein 63 (TP63) has been reported to bind to the transcription of SLC26A1 gene in health condition, which leads to an affected expression of the drug transporter Sulfate anion transporter 1.
Class6.7: Grainyhead domain factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
GRHL2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[5]
TF Protein Name	Grainyhead-like protein 2 homolog		Transcription Factor Info
Tissue	Bronchus; Ovary; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
GRHL3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	Grainyhead-like protein 3 homolog		Transcription Factor Info
Tissue	Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Grainyhead-like protein 3 homolog (GRHL3) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.
TF Superclass8: beta-Sheet binding to DNA
Class8.1: TATA-binding proteins		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TBP		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC26A1 gene			[1]
TF Protein Name	TATA-box-binding protein		Transcription Factor Info
Tissue	Bone marrow; Cervix; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	TATA-box-binding protein (TBP) can directly bind to the SLC26A1 gene, which in turn affects the expression or function of the drug transporter Sulfate anion transporter 1.

References
1	The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
2	Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis. J Biol Chem. 2012;287(40):33533-44.
3	NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
4	hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-313. (ID:ENSG00000145217)
5	Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
6	c-Jun binding site identification in K562 cells. J Genet Genomics. 2011;38(6):235-42.
7	Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
8	Integrated expression profiling and ChIP-seq analyses of the growth inhibition response program of the androgen receptor. PLoS One. 2009;4(8):e6589.
9	Mapping of HNF4alpha target genes in intestinal epithelial cells. BMC Gastroenterol. 2009;9:68.
10	Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing. Electrophoresis. 2010;31(17):2936-43.
11	Transcriptional profiling of the zebrafish proximal tubule. Am J Physiol Renal Physiol. 2019 Aug 1;317(2):F478-F488.
12	Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res. 2012;40(15):7190-206.

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