Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0383 Transporter Info
Gene Name	SLC4A2
Transporter Name	Anion exchange protein 2
Gene ID	6522
UniProt ID	P04920

Post-Translational Modification of This DT
Overview ofSLC4A2 Modification Sites with Functional and Structural Information
Sequence	M S S A P R R P A K G A D S F C T P E P E S L G P G T P G F P E Q E E D E L H R T L G V E R F E E I L Q E A G S R G G E E P G R S Y G E E D F E Y H R Q S S H H I H H P L S T H L P P D A R R R K T P Q G P G R K P R R R P G A S P T G E T P T I E E G E E D E D E A S E A E G A R A L T Q P S P V S T P S S V Q F F L Q E D D S A D R K A E R T S P S S P A P L P H Q E A T P R A S K G A Q A G T Q V E E A E A E A V A V A S G T A G G D D G G A S G R P L P K A Q P G H R S Y N L Q E R R R I G S M T G A E Q A L L P R V P T D E I E A Q T L A T A D L D L M K S H R F E D V P G V R R H L V R K N A K G S T Q S G R E G R E P G P T P R A R P R A P H K P H E V F V E L N E L L L D K N Q E P Q W R E T A R W I K F E E D V E E E T E R W G K P H V A S L S F R S L L E L R R T L A H G A V L L D L D Q Q T L P G V A H Q V V E Q M V I S D Q I K A E D R A N V L R A L L L K H S H P S D E K D F S F P R N I S A G S L G S L L G H H H G Q G A E S D P H V T E P L M G G V P E T R L E V E R E R E L P P P A P P A G I T R S K S K H E L K L L E K I P E N A E A T V V L V G C V E F L S R P T M A F V R L R E A V E L D A V L E V P V P V R F L F L L L G P S S A N M D Y H E I G R S I S T L M S D K Q F H E A A Y L A D E R E D L L T A I N A F L D C S V V L P P S E V Q G E E L L R S V A H F Q R Q M L K K R E E Q G R L L P T G A G L E P K S A Q D K A L L Q M V E A A G A A E D D P L R R T G R P F G G L I R D V R R R Y P H Y L S D F R D A L D P Q C L A A V I F I Y F A A L S P A I T F G G L L G E K T Q D L I G V S E L I M S T A L Q G V V F C L L G A Q P L L V I G F S G P L L V F E E A F F S F C S S N H L E Y L V G R V W I G F W L V F L A L L M V A L E G S F L V R F V S R F T Q E I F A F L I S L I F I Y E T F Y K L V K I F Q E H P L H G C S A S N S S E V D G G E N M T W A G A R P T L G P G N R S L A G Q S G Q G K P R G Q P N T A L L S L V L M A G T F F I A F F L R K F K N S R F F P G R I R R V I G D F G V P I A I L I M V L V D Y S I E D T Y T Q K L S V P S G F S V T A P E K R G W V I N P L G E K S P F P V W M M V A S L L P A I L V F I L I F M E T Q I T T L I I S K K E R M L Q K G S G F H L D L L L I V A M G G I C A L F G L P W L A A A T V R S V T H A N A L T V M S K A V A P G D K P K I Q E V K E Q R V T G L L V A L L V G L S I V I G D L L R Q I P L A V L F G I F L Y M G V T S L N G I Q F Y E R L H L L L M P P K H H P D V T Y V K K V R T L R M H L F T A L Q L L C L A L L W A V M S T A A S L A F P F I L I L T V P L R M V V L T R I F T D R E M K C L D A N E A E P V F D E R E G V D E Y N E M P M P V
PTM type	X-Methylation X-Methylation X-N-glycosylation X-Phosphorylation X-S-nitrosylation X-Sulfoxidation X-Ubiquitination X-Ubiquitination X: Amino Acid

Methylation
Arginine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[1]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	57
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC4A2 Arginine 57 has the potential to affect its expression or activity.
PTM Phenomenon2	.			[2]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	301
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC4A2 Arginine 301 has the potential to affect its expression or activity.
Lysine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[3]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	274
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC4A2 Lysine 274 has the potential to affect its expression or activity.
N-glycosylation
Asparagine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[1]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	859
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A2 Asparagine 859 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A2			[1]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	868
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A2 Asparagine 868 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A2			[1]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	882
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A2 Asparagine 882 has the potential to affect its expression or activity.
Phosphorylation
Glutamicacid	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[4]
Role of PTM	Potential impacts
Modified Residue	Glutamicacid	Modified Location	72
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Glutamicacid 72 has the potential to affect its expression or activity.
Serine	35 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	14
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 14 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A2			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	22
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 22 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A2			[6], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	56
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 56 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A2			[8], [9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	65
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 65 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	77
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 77 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	78
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 78 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	86
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 86 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A2			[11], [12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	113
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 113 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A2			[13], [14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	132
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 132 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A2			[11], [13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	144
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 144 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A2			[11], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	147
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 147 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC4A2			[11], [13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	150
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 150 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC4A2			[11], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	151
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 151 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC4A2			[16], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	161
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 161 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC4A2			[13], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	170
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 170 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC4A2			[13], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	172
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 172 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence SLC4A2			[13], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	173
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 173 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence SLC4A2			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	187
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 187 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence SLC4A2			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	219
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 219 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence SLC4A2			[10], [21]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	232
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 232 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence SLC4A2			[13], [14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	243
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 243 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence SLC4A2			[10], [22]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	275
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 275 has the potential to affect its expression or activity.
PTM Phenomenon23	Have the potential to influence SLC4A2			[23]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	296
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 296 has the potential to affect its expression or activity.
PTM Phenomenon24	Have the potential to influence SLC4A2			[23], [24]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	299
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 299 has the potential to affect its expression or activity.
PTM Phenomenon25	Have the potential to influence SLC4A2			[25]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	367
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 367 has the potential to affect its expression or activity.
PTM Phenomenon26	Have the potential to influence SLC4A2			[25], [26]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	369
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 369 has the potential to affect its expression or activity.
PTM Phenomenon27	Have the potential to influence SLC4A2			[25]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	372
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 372 has the potential to affect its expression or activity.
PTM Phenomenon28	Have the potential to influence SLC4A2			[13], [14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	443
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 443 has the potential to affect its expression or activity.
PTM Phenomenon29	Have the potential to influence SLC4A2			[13], [27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	446
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 446 has the potential to affect its expression or activity.
PTM Phenomenon30	Have the potential to influence SLC4A2			[13], [27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	449
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 449 has the potential to affect its expression or activity.
PTM Phenomenon31	Have the potential to influence SLC4A2			[13], [27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	461
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 461 has the potential to affect its expression or activity.
PTM Phenomenon32	Have the potential to influence SLC4A2			[28]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	500
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 500 has the potential to affect its expression or activity.
PTM Phenomenon33	Have the potential to influence SLC4A2			[29]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	577
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 577 has the potential to affect its expression or activity.
PTM Phenomenon34	Have the potential to influence SLC4A2			[29]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	581
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 581 has the potential to affect its expression or activity.
PTM Phenomenon35	Have the potential to influence SLC4A2			[30]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	654
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Serine 654 has the potential to affect its expression or activity.
Threonine	20 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[5]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	17
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 17 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A2			[31], [32]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	27
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 27 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A2			[10]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	87
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 87 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A2			[13], [15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	115
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 115 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A2			[13], [15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	118
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 118 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A2			[13], [15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	120
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 120 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A2			[11], [33]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	141
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 141 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A2			[11], [13]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	148
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 148 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A2			[18], [34]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	169
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 169 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A2			[14], [34]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	183
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 183 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A2			[20]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	194
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 194 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC4A2			[8], [34]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	245
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 245 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC4A2			[8], [35]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 257 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC4A2			[36], [37]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	264
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 264 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC4A2			[37]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	267
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 267 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC4A2			[23]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	297
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 297 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence SLC4A2			[23]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	309
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 309 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence SLC4A2			[27], [38]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	466
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 466 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence SLC4A2			[36], [39]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	476
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 476 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence SLC4A2			[29]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	578
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Threonine 578 has the potential to affect its expression or activity.
Tyrosine	4 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[8], [40]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	66
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Tyrosine 66 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A2			[8], [41]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	73
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Tyrosine 73 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A2			[10], [21]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	233
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Tyrosine 233 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A2			[8], [40]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1234
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A2 Tyrosine 1234 has the potential to affect its expression or activity.
S-nitrosylation
Cystine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[42]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	16
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC4A2 Cystine 16 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A2			[42]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1215
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC4A2 Cystine 1215 has the potential to affect its expression or activity.
Sulfoxidation
Methionine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A2			[43]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	244
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC4A2 Methionine 244 has the potential to affect its expression or activity.
Ubiquitination
Lysine	16 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	334
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 334 has the potential to affect its expression or activity.
PTM Phenomenon2	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	362
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 362 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	362
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 362 has the potential to affect its expression or activity.
PTM Phenomenon4	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	362
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 362 has the potential to affect its expression or activity.
PTM Phenomenon5	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	426
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 426 has the potential to affect its expression or activity.
PTM Phenomenon6	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	434
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 434 has the potential to affect its expression or activity.
PTM Phenomenon7	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	434
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 434 has the potential to affect its expression or activity.
PTM Phenomenon8	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	434
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 434 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	653
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 653 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	658
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 658 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	893
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 893 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	975
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 975 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1073
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 1073 has the potential to affect its expression or activity.
PTM Phenomenon14	.			[44]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1080
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 1080 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1087
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 1087 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC4A2			[45], [46]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1156
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A2 Lysine 1156 has the potential to affect its expression or activity.

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