Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0191 Transporter Info
Gene Name	SLC25A3
Transporter Name	Phosphate carrier protein
Gene ID	5250
UniProt ID	Q00325

Post-Translational Modification of This DT
Overview ofSLC25A3 Modification Sites with Functional and Structural Information
Sequence	M F S S V A H L A R A N P F N T P H L Q L V H D G L G D L R S S S P G P T G Q P R R P R N L A A A A V E E Q Y S C D Y G S G R F F I L C G L G G I I S C G T T H T A L V P L D L V K C R M Q V D P Q K Y K G I F N G F S V T L K E D G V R G L A K G W A P T F L G Y S M Q G L C K F G F Y E V F K V L Y S N M L G E E N T Y L W R T S L Y L A A S A S A E F F A D I A L A P M E A A K V R I Q T Q P G Y A N T L R D A A P K M Y K E E G L K A F Y K G V A P L W M R Q I P Y T M M K F A C F E R T V E A L Y K F V V P K P R S E C S K P E Q L V V T F V A G Y I A G V F C A I V S H P A D S V V S V L N K E K G S S A S L V L K R L G F K G V W K G L F A R I I M I G T L T A L Q W F I Y D S V K V Y F R L P R P P P P E M P E S L K K K L G L T Q
PTM type	X-Acetylation X-Malonylation X-Methylation X-Oxidation X-Phosphorylation X-Phosphorylation X-S-nitrosylation X-S-palmitoylation X-S-sulfenylation X-S-sulfhydration X-Succinylation X-Sulfoxidation X-Ubiquitination X: Amino Acid

Acetylation
Lysine	14 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	99
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 99 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[2]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	101
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 101 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[2], [3]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	112
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 112 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[2], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	206
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 206 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A3			[4], [5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	209
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 209 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A3			[4], [6]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	214
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 214 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A3			[2], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	218
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 218 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A3			[2], [3]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	234
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 234 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A3			[2], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	247
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 247 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC25A3			[3]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	295
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 295 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC25A3			[2], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	304
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 304 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC25A3			[7]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	309
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 309 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC25A3			[2]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	355
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 355 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC25A3			[8]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	356
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A3 Lysine 356 has the potential to affect its expression or activity.
Malonylation
Lysine	5 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[9]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	206
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A3 Lysine 206 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[9]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	209
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A3 Lysine 209 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[10]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	214
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A3 Lysine 214 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[9]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	295
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A3 Lysine 295 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A3			[9]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	304
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A3 Lysine 304 has the potential to affect its expression or activity.
Methylation
Arginine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[11]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	117
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A3 Arginine 117 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[11]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	201
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A3 Arginine 201 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[11]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	226
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A3 Arginine 226 has the potential to affect its expression or activity.
Lysine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[12]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	112
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A3 Lysine 112 has the potential to affect its expression or activity.
Oxidation
Cystine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[13], [14]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	136
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC25A3 Cystine 136 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[13]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	237
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC25A3 Cystine 237 has the potential to affect its expression or activity.
Phosphorylation
Serine	10 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	3
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 3 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[15], [16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	4
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 4 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[17], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	31
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 31 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[17], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	32
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 32 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A3			[18], [19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	33
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 33 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A3			[20], [21]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	108
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 108 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A3			[22], [23]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	297
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 297 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A3			[22], [24]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	298
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 298 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A3			[22]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	300
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 300 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC25A3			[25]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	353
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Serine 353 has the potential to affect its expression or activity.
Threonine	4 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[20], [26]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	110
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Threonine 110 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[27], [28]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	192
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Threonine 192 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[27], [29]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	199
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Threonine 199 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	231
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Threonine 231 has the potential to affect its expression or activity.
Tyrosine	8 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[20]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	100
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 100 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[30]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	141
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 141 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[31]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	158
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 158 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[27], [32]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	196
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 196 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A3			[33]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	208
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 208 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A3			[34], [35]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	217
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 217 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A3			[15]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	230
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 230 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A3			[36]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	246
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A3 Tyrosine 246 has the potential to affect its expression or activity.
S-nitrosylation
Cystine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[37]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	136
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC25A3 Cystine 136 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[38], [39]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	237
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC25A3 Cystine 237 has the potential to affect its expression or activity.
S-palmitoylation
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[40]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	237
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-palmitoylation at SLC25A3 Cystine 237 has the potential to affect its expression or activity.
S-sulfenylation
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[41]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	237
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-sulfenylation (-SOH) at SLC25A3 Cystine 237 has the potential to affect its expression or activity.
S-sulfhydration
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[42]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	237
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-sulfhydration (-SSH) at SLC25A3 Cystine 237 has the potential to affect its expression or activity.
Succinylation
Lysine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[4], [43]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	209
Experimental Method	Co-Immunoprecipitation
Detailed Description	Succinylation at SLC25A3 Lysine 209 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[43]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	234
Experimental Method	Co-Immunoprecipitation
Detailed Description	Succinylation at SLC25A3 Lysine 234 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[43]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	247
Experimental Method	Co-Immunoprecipitation
Detailed Description	Succinylation at SLC25A3 Lysine 247 has the potential to affect its expression or activity.
Sulfoxidation
Methionine	4 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[44]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	151
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A3 Methionine 151 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[44]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	207
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A3 Methionine 207 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[45]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	225
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A3 Methionine 225 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[44]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	321
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A3 Methionine 321 has the potential to affect its expression or activity.
Ubiquitination
Lysine	16 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	99
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 99 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	101
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 101 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	112
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 112 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	121
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 121 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	206
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 206 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	209
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 209 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	214
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 214 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	218
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 218 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	234
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 234 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	247
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 247 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	252
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 252 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	295
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 295 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	304
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 304 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	309
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 309 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	355
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 355 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC25A3			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	357
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A3 Lysine 357 has the potential to affect its expression or activity.

References
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19	Improved Method for Determining Absolute Phosphorylation Stoichiometry Using Bayesian Statistics and Isobaric Labeling. J Proteome Res. 2017 Nov 3;16(11):4217-4226.
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25	Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates. Cell Metab. 2015 Nov 3;22(5):922-35.
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40	Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites. J Proteome Res. 2018 May 4;17(5):1907-1922.
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45	Oxidation of protein-bound methionine in Photofrin-photodynamic therapy-treated human tumor cells explored by methionine-containing peptide enrichment and quantitative proteomics approach. Sci Rep. 2017 May 2;7(1):1370.
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47	Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 2011 Oct 21;44(2):325-40.

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