Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0043 Transporter Info
Gene Name	ABCA5
Transporter Name	ATP-binding cassette sub-family A member 5
Gene ID	23461
UniProt ID	Q8WWZ7

Post-Translational Modification of This DT
Overview ofABCA5 Modification Sites with Functional and Structural Information
Sequence	M S T A I R E V G V W R Q T R T L L L K N Y L I K C R T K K S S V Q E I L F P L F F L F W L I L I S M M H P N K K Y E E V P N I E L N P M D K F T L S N L I L G Y T P V T N I T S S I M Q K V S T D H L P D V I I T E E Y T N E K E M L T S S L S K P S N F V G V V F K D S M S Y E L R F F P D M I P V S S I Y M D S R A G C S K S C E A A Q Y W S S G F T V L Q A S I D A A I I Q L K T N V S L W K E L E S T K A V I M G E T A V V E I D T F P R G V I L I Y L V I A F S P F G Y F L A I H I V A E K E K K I K E F L K I M G L H D T A F W L S W V L L Y T S L I F L M S L L M A V I A T A S L L F P Q S S S I V I F L L F F L Y G L S S V F F A L M L T P L F K K S K H V G I V E F F V T V A F G F I G L M I I L I E S F P K S L V W L F S P F C H C T F V I G I A Q V M H L E D F N E G A S F S N L T A G P Y P L I I T I I M L T L N S I F Y V L L A V Y L D Q V I P G E F G L R R S S L Y F L K P S Y W S K S K R N Y E E L S E G N V N G N I S F S E I I E P V S S E F V G K E A I R I S G I Q K T Y R K K G E N V E A L R N L S F D I Y E G Q I T A L L G H S G T G K S T L M N I L C G L C P P S D G F A S I Y G H R V S E I D E M F E A R K M I G I C P Q L D I H F D V L T V E E N L S I L A S I K G I P A N N I I Q E V Q K V L L D L D M Q T I K D N Q A K K L S G G Q K R K L S L G I A V L G N P K I L L L D E P T A G M D P C S R H I V W N L L K Y R K A N R V T V F S T H F M D E A D I L A D R K A V I S Q G M L K C V G S S M F L K S K W G I G Y R L S M Y I D K Y C A T E S L S S L V K Q H I P G A T L L Q Q N D Q Q L V Y S L P F K D M D K F S G L F S A L D S H S N L G V I S Y G V S M T T L E D V F L K L E V E A E I D Q A D Y S V F T Q Q P L E E E M D S K S F D E M E Q S L L I L S E T K A A L V S T M S L W K Q Q M Y T I A K F H F F T L K R E S K S V R S V L L L L L I F F T V Q I F M F L V H H S F K N A V V P I K L V P D L Y F L K P G D K P H K Y K T S L L L Q N S A D S D I S D L I S F F T S Q N I M V T M I N D S D Y V S V A P H S A A L N V M H S E K D Y V F A A V F N S T M V Y S L P I L V N I I S N Y Y L Y H L N V T E T I Q I W S T P F F Q E I T D I V F K I E L Y F Q A A L L G I I V T A M P P Y F A M E N A E N H K I K A Y T Q L K L S G L L P S A Y W I G Q A V V D I P L F F I I L I L M L G S L L A F H Y G L Y F Y T V K F L A V V F C L I G Y V P S V I L F T Y I A S F T F K K I L N T K E F W S F I Y S V A A L A C I A I T E I T F F M G Y T I A T I L H Y A F C I I I P I Y P L L G C L I S F I K I S W K N V R K N V D T Y N P W D R L S V A V I S P Y L Q C V L W I F L L Q Y Y E K K Y G G R S I R K D P F F R N L S T K S K N R K L P E P P D N E D E D E D V K A E R L K V K E L M G C Q C C E E K P S I M V S N L H K E Y D D K K D F L L S R K V K K V A T K Y I S F C V K K G E I L G L L G P N G A G K S T I I N I L V G D I E P T S G Q V F L G D Y S S E T S E D D D S L K C M G Y C P Q I N P L W P D T T L Q E H F E I Y G A V K G M S A S D M K E V I S R I T H A L D L K E H L Q K T V K K L P A G I K R K L C F A L S M L G N P Q I T L L D E P S T G M D P K A K Q H M W R A I R T A F K N R K R A A I L T T H Y M E E A E A V C D R V A I M V S G Q L R C I G T V Q H L K S K F G K G Y F L E I K L K D W I E N L E V D R L Q R E I Q Y I F P N A S R Q E S F S S I L A Y K I P K E D V Q S L S Q S F F K L E E A K H A F A I E E Y S F S Q A T L E Q V F V E L T K E Q E E E D N S C G T L N S T L W W E R T Q E D R V V F
PTM type	X-Acetylation X-Methylation X-N-glycosylation X-Oxidation X-Phosphorylation X-Ubiquitination X: Amino Acid

Acetylation
Lysine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	614
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at ABCA5 Lysine614 have been reported to have the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	620
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at ABCA5 Lysine620 have been reported to have the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1438
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at ABCA5 Lysine1438 have been reported to have the potential to affect its expression or activity.
Methylation
Arginine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	.			[2]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	218
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at ABCA5 Arginine 218 has the potential to affect its expression or activity.
N-glycosylation
Asparagine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	86
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA5 Asparagine 86 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	458
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA5 Asparagine 458 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	996
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA5 Asparagine 996 has the potential to affect its expression or activity.
Oxidation
Cystine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	648
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCA5 Cystine 648 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1322
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCA5 Cystine 1322 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1513
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCA5 Cystine 1513 has the potential to affect its expression or activity.
Phosphorylation
Serine	25 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[5], [6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	134
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 134 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[5], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	136
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 136 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[5], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	149
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 149 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA5			[5], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	150
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 150 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA5			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	155
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 155 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA5			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	192
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 192 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCA5			[9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	462
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 462 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCA5			[9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	469
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 469 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCA5			[9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	470
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 470 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCA5			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	546
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 546 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCA5			[11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	616
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 616 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	624
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 624 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	649
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 649 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCA5			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	669
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 669 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence ABCA5			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	687
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 687 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence ABCA5			[12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	815
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 815 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence ABCA5			[13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	827
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 827 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	859
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 859 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence ABCA5			[14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1185
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1185 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1405
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1405 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1407
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1407 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence ABCA5			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1414
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1414 has the potential to affect its expression or activity.
PTM Phenomenon23	Have the potential to influence ABCA5			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1562
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1562 has the potential to affect its expression or activity.
PTM Phenomenon24	Have the potential to influence ABCA5			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1564
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1564 has the potential to affect its expression or activity.
PTM Phenomenon25	Have the potential to influence ABCA5			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1565
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Serine 1565 has the potential to affect its expression or activity.
Threonine	6 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[8]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	208
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Threonine 208 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	642
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Threonine 642 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[5]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	666
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Threonine 666 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA5			[5]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	670
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Threonine 670 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA5			[3]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	854
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Threonine 854 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA5			[15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1417
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Threonine 1417 has the potential to affect its expression or activity.
Tyrosine	6 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[17]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	22
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Tyrosine 22 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[17]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	58
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Tyrosine 58 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[5], [18]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	137
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Tyrosine 137 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA5			[5], [7]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	152
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Tyrosine 152 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA5			[19]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1299
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Tyrosine 1299 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA5			[16]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1569
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA5 Tyrosine 1569 has the potential to affect its expression or activity.
Ubiquitination
Lysine	11 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	490
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 490 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	608
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 608 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	910
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 910 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1050
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1050 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1254
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1254 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1302
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1302 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1303
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1303 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCA5			[20], [21]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1410
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1410 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1423
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1423 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1428
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1428 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCA5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1585
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA5 Lysine 1585 has the potential to affect its expression or activity.

References
1	Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Cell Rep. 2012 Aug 30;2(2):419-31.
2	ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins. Nucleic Acids Res. 2018;46(D1):D901-D910.
3	dbPTM in 2022: an updated database for exploring regulatory networks and functional associations of protein post-translational modifications. Nucleic Acids Res. 2022 Jan 7;50(D1):D471-D479. (ID: ABCA5_HUMAN)
4	A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. 2020 Mar 5;180(5):968-983.e24.
5	Selective Enrichment of Cysteine-Containing Phosphopeptides for Subphosphoproteome Analysis. J Proteome Res. 2015 Dec 4;14(12):5341-7.
6	Candidatus Phytoplasma noviguineense, a novel taxon associated with Bogia coconut syndrome and banana wilt disease on the island of New Guinea. Int J Syst Evol Microbiol. 2018 Jan;68(1):170-175.
7	Citric acid-assisted two-step enrichment with TiO2 enhances the separation of multi- and monophosphorylated peptides and increases phosphoprotein profiling. J Proteome Res. 2013 Jun 7;12(6):2467-76.
8	Comparison of SILAC and mTRAQ quantification for phosphoproteomics on a quadrupole orbitrap mass spectrometer. J Proteome Res. 2013 Sep 6;12(9):4089-100.
9	Integrated analysis of global proteome, phosphoproteome, and glycoproteome enables complementary interpretation of disease-related protein networks. Sci Rep. 2015 Dec 11;5:18189.
10	Quantitative phosphoproteomics analysis reveals a key role of insulin growth factor 1 receptor (IGF1R) tyrosine kinase in human sperm capacitation. Mol Cell Proteomics. 2015 Apr;14(4):1104-12.
11	HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies. J Proteome Res. 2014 Nov 7;13(11):5230-9.
12	Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors. Mol Syst Biol. 2018 Mar 5;14(3):e7858.
13	Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells. Sci Signal. 2013 Mar 26;6(268):rs6.
14	Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics. 2014 Jul;13(7):1690-704.
15	Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway. Mol Biosyst. 2013 Apr 5;9(4):732-49.
16	Phosphoproteome Analysis Reveals Differential Mode of Action of Sorafenib in Wildtype and Mutated FLT3 Acute Myeloid Leukemia (AML) Cells. Mol Cell Proteomics. 2017 Jul;16(7):1365-1376.
17	Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell. 2007 Dec 14;131(6):1190-203.
18	Phylogenomic analysis of Balantidium ctenopharyngodoni (Ciliophora, Litostomatea) based on single-cell transcriptome sequencing. Parasite. 2017;24:43.
19	Changes in the ultrastructure of the iris after irradiation with intense light. A study of long-term effects after irradiation with argon ion, Nd:YAG and Q-switched ruby lasers. Adv Ophthalmol. 1979;39:59-180.
20	UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat Struct Mol Biol. 2018 Jul;25(7):631-640.
21	Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. Nat Struct Mol Biol. 2020 Feb;27(2):210-220.

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Detail Information of Post-Translational Modifications

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