Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0382 Transporter Info
Gene Name	SLC4A11
Transporter Name	Sodium bicarbonate transporter-like protein 11
Gene ID	83959
UniProt ID	Q8NBS3

Post-Translational Modification of This DT
Overview ofSLC4A11 Modification Sites with Functional and Structural Information
Sequence	M S Q V G G R G D R C T Q E V Q G L V H G A G D L S A S L A E N S P T M S Q N G Y F E D S S Y Y K C D T D D T F E A R E E I L G D E A F D T A N S S I V S G E S I R F F V N V N L E M Q A T N T E N E A T S G G C V L L H T S R K Y L K L K N F K E E I R A H R D L D G F L A Q A S I V L N E T A T S L D N V L R T M L R R F A R D P D N N E P N C N L D L L M A M L F T D A G A P M R G K V H L L S D T I Q G V T A T V T G V R Y Q Q S W L C I I C T M K A L Q K R H V C I S R L V R P Q N W G E N S C E V R F V I L V L A P P K M K S T K T A M E V A R T F A T M F S D I A F R Q K L L E T R T E E E F K E A L V H Q R Q L L T M V S H G P V A P R T K E R S T V S L P A H R H P E P P K C K D F V P F G K G I R E D I A R R F P L Y P L D F T D G I I G K N K A V G K Y I T T T L F L Y F A C L L P T I A F G S L N D E N T D G A I D V Q K T I A G Q S I G G L L Y A L F S G Q P L V I L L T T A P L A L Y I Q V I R V I C D D Y D L D F N S F Y A W T G L W N S F F L A L Y A F F N L S L V M S L F K R S T E E I I A L F I S I T F V L D A V K G T V K I F W K Y Y Y G H Y L D D Y H T K R T S S L V S L S G L G A S L N A S L H T A L N A S F L A S P T E L P S A T H S G Q A T A V L S L L I M L G T L W L G Y T L Y Q F K K S P Y L H P C V R E I L S D C A L P I A V L A F S L I S S H G F R E I E M S K F R Y N P S E S P F A M A Q I Q S L S L R A V S G A M G L G F L L S M L F F I E Q N L V A A L V N A P E N R L V K G T A Y H W D L L L L A I I N T G L S L F G L P W I H A A Y P H S P L H V R A L A L V E E R V E N G H I Y D T I V N V K E T R L T S L G A S V L V G L S L L L L P V P L Q W I P K P V L Y G L F L Y I A L T S L D G N Q L V Q R V A L L L K E Q T A Y P P T H Y I R R V P Q R K I H Y F T G L Q V L Q L L L L C A F G M S S L P Y M K M I F P L I M I A M I P I R Y I L L P R I I E A K Y L D V M D A E H R P
PTM type	X-N-glycosylation X-Phosphorylation X-Phosphorylation X-Ubiquitination X-Ubiquitination X: Amino Acid

N-glycosylation
Asparagine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[1]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	545
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A11 Asparagine 545 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[1]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	553
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A11 Asparagine 553 has the potential to affect its expression or activity.
Phosphorylation
Asparagine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[2]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	553
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Asparagine 553 has the potential to affect its expression or activity.
Serine	12 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[3], [4]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	73
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 73 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[3], [5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	74
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 74 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A11			[3], [5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	77
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 77 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A11			[6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	213
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 213 has the potential to affect its expression or activity.
PTM Phenomenon5	.			[7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	261
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 261 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A11			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	321
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 321 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A11			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	324
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 324 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A11			[2]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	484
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 484 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A11			[2]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	555
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 555 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A11			[9], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	652
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 652 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A11			[9], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	654
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 654 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	795
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Serine 795 has the potential to affect its expression or activity.
Threonine	6 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[3]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	70
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Threonine 70 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[6]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	220
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Threonine 220 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[7]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	255
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Threonine 255 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A11			[8]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	322
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Threonine 322 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A11			[2], [11]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	528
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Threonine 528 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	794
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Threonine 794 has the potential to affect its expression or activity.
Tyrosine	11 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[6]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	210
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 210 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	517
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 517 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	518
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 518 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	519
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 519 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	522
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 522 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A11			[2], [11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	526
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 526 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A11			[9]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	638
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 638 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A11			[12]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	745
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 745 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	785
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 785 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A11			[11]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	790
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 790 has the potential to affect its expression or activity.
PTM Phenomenon11	.			[7]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	804
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A11 Tyrosine 804 has the potential to affect its expression or activity.
Ubiquitination
Alanine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Alanine	Modified Location	371
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Alanine 371 has the potential to affect its expression or activity.
Glutamicacid	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Glutamicacid	Modified Location	736
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Glutamicacid 736 has the potential to affect its expression or activity.
Isoleucine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[16]
Role of PTM	Potential impacts
Modified Residue	Isoleucine	Modified Location	279
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Isoleucine 279 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Isoleucine	Modified Location	779
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Isoleucine 779 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Isoleucine	Modified Location	857
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Isoleucine 857 has the potential to affect its expression or activity.
Leucine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Residue	Leucine	Modified Location	756
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Leucine 756 has the potential to affect its expression or activity.
Lysine	11 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	.			[7]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	268
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 268 has the potential to affect its expression or activity.
PTM Phenomenon2	.			[17]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	284
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 284 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[17]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	284
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 284 has the potential to affect its expression or activity.
PTM Phenomenon4	.			[17]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	284
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 284 has the potential to affect its expression or activity.
PTM Phenomenon5	.			[17]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	284
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 284 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	295
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 295 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	344
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 344 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	635
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 635 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	752
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 752 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	810
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 810 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	880
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Lysine 880 has the potential to affect its expression or activity.
Methionine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	662
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Methionine 662 has the potential to affect its expression or activity.
Proline	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Residue	Proline	Modified Location	775
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Proline 775 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Proline	Modified Location	859
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Proline 859 has the potential to affect its expression or activity.
Serine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	725
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Serine 725 has the potential to affect its expression or activity.
Threonine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[16]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	322
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Threonine 322 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	794
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Threonine 794 has the potential to affect its expression or activity.
Tryptophan	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Tryptophan	Modified Location	698
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Tryptophan 698 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Tryptophan	Modified Location	717
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Tryptophan 717 has the potential to affect its expression or activity.
Valine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Residue	Valine	Modified Location	783
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Valine 783 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Residue	Valine	Modified Location	837
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 Valine 837 has the potential to affect its expression or activity.
Unclear Residue	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A11			[13]
Role of PTM	Potential impacts
Modified Location	907
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 907 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Location	915
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 915 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A11			[15]
Role of PTM	Potential impacts
Modified Location	917
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A11 917 has the potential to affect its expression or activity.

References
1	dbPTM in 2022: an updated database for exploring regulatory networks and functional associations of protein post-translational modifications. Nucleic Acids Res. 2022 Jan 7;50(D1):D471-D479. (ID: S4A11_HUMAN)
2	Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics. 2014 Jul;13(7):1690-704.
3	Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun. 2017 Mar 28;8:14864.
4	Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics. 2012 Sep;11(9):651-68.
5	Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. EMBO J. 2015 Nov 12;34(22):2840-61.
6	Quantitative Proteomics Reveals the Dynamics of Protein Phosphorylation in Human Bronchial Epithelial Cells during Internalization, Phagosomal Escape, and Intracellular Replication of Staphylococcus aureus. J Proteome Res. 2016 Dec 2;15(12):4369-4386.
7	15 years of PhosphoSitePlus?: integrating post-translationally modified sites, disease variants and isoforms. Nucleic Acids Res. 2019;47(D1):D433-D441.
8	Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-beta. Sci Signal. 2014 Jul 22;7(335):rs5.
9	iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics. Mol Cell Proteomics. 2012 Jun;11(6):M111.014423.
10	Activation of diverse signalling pathways by oncogenic PIK3CA mutations. Nat Commun. 2014 Sep 23;5:4961.
11	Characterization of native protein complexes and protein isoform variation using size-fractionation-based quantitative proteomics. Mol Cell Proteomics. 2013 Dec;12(12):3851-73.
12	Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling. Mol Cell Proteomics. 2016 Aug;15(8):2671-85.
13	Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 2011 Oct 21;44(2):325-40.
14	Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes. Cell Syst. 2016 Oct 26;3(4):395-403.e4.
15	Global identification of modular cullin-RING ligase substrates. Cell. 2011 Oct 14;147(2):459-74.
16	UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat Struct Mol Biol. 2018 Jul;25(7):631-640.
17	ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins. Nucleic Acids Res. 2018;46(D1):D901-D910.

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Detail Information of Post-Translational Modifications

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