Detail Information of Mutation-induced Spatial Variation
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0511 Transporter Info | ||||
| Gene Name | KCNJ11 | ||||
| Transporter Name | ATP-sensitive inward rectifier potassium channel 11 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Mutation-induced Structural Variation (MSV) of This DT | |||||
| PDB ID | |||||
| Expression System | Homo sapiens | ||||
| Method | EM | ||||
| Resolution | 3.1 Å | ||||
| Corresponding chain | A/B/C/D | ||||
| Mutation Site(s) | C166S; G334D | [1] | |||
| Structure Details | |||||
| Modeling Method | EM | ||||
| Publication year | 2021 | ||||
| PDB ID | Scanning Method | Resolution | Mutation Sites | Details | Ref |
| 7S5T | EM | 3.1 Å | C166S; G334D | [1] | |
| Structure | |||||
| Expression System | Homo sapiens | ||||
| Corresponding chain | A/B/C/D | ||||
| Sequence Length | 1-390 | Mutation | Yes | ||
| References | |||||
| 1 | Molecular structure of an open human K(ATP) channel. Proc Natl Acad Sci U S A. 2021;118(48). | ||||
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