Detail Information of Mutation-induced Spatial Variation
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0383 Transporter Info | ||||
| Gene Name | SLC4A2 | ||||
| Transporter Name | Anion exchange protein 2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Mutation-induced Structural Variation (MSV) of This DT | |||||
| PDB ID | |||||
| Expression System | Homo sapiens | ||||
| Method | EM | ||||
| Resolution | 3.3 Å | ||||
| Corresponding chain | A/B | ||||
| Mutation Site(s) | R932A; K1147A; H1148A | [1] | |||
| Structure Details | |||||
| Modeling Method | EM | ||||
| Publication year | 2024 | ||||
| PDB ID | Scanning Method | Resolution | Mutation Sites | Details | Ref |
| 8JNJ | EM | 3.3 Å | R932A; K1147A; H1148A | [1] | |
| Structure | |||||
| Expression System | Homo sapiens | ||||
| Corresponding chain | A/B | ||||
| Sequence Length | 1-1241 | Mutation | Yes | ||
| References | |||||
| 1 | Structural and functional insights into the lipid regulation of human anion exchanger 2. Nat Commun. 2024;15(1):759. | ||||
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