Detail Information of Mutation-induced Spatial Variation
General Information of Drug Transporter (DT) | |||||
---|---|---|---|---|---|
DT ID | DTD0269 Transporter Info | ||||
Gene Name | SLC30A1 | ||||
Transporter Name | Zinc transporter 1 | ||||
Gene ID | |||||
UniProt ID | |||||
Mutation-induced Structural Variation (MSV) of This DT | |||||
PDB ID | |||||
Expression System | Homo sapiens | ||||
Method | EM | ||||
Resolution | 3.4 Å | ||||
Corresponding chain | A/B | ||||
Mutation Site(s) | D47N; D255N | [1] | |||
Structure Details | |||||
Modeling Method | EM | ||||
Publication year | 2024 | ||||
PDB ID | Scanning Method | Resolution | Mutation Sites | Details | Ref |
8J2G | EM | 3.4 Å | D47N; D255N | [1] | |
Structure | |||||
Expression System | Homo sapiens | ||||
Corresponding chain | A/B | ||||
Sequence Length | 1-507 | Mutation | Yes | ||
References | |||||
1 | Structural insights into the calcium-coupled zinc export of human ZnT1. Sci Adv. 2024;10(17):eadk5128. | ||||
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