Detail Information of Mutation-induced Spatial Variation

General Information of Drug Transporter (DT)
DT ID	DTD0052 Transporter Info
Gene Name	ABCB6
Transporter Name	ATP-binding cassette sub-family B member 6
Gene ID	10058
UniProt ID	Q9NP58
Mutation-induced Structural Variation (MSV) of This DT
Click to Save PDB File in TXT Format	PDB ID		8K7C
	Expression System		Trichoplusia ni
	Method		EM
	Resolution		3.9 Å
	Corresponding chain		A/B
	Mutation Site(s)		W307A		[1]
	Structure Details		Click to Show/Hide the Details
Modeling Method	EM
Publication year	2023
Click to Save PDB File in TXT Format	PDB ID		8K7B
	Expression System		Trichoplusia ni
	Method		EM
	Resolution		3.9 Å
	Corresponding chain		A/B
	Mutation Site(s)		W309A		[1]
	Structure Details		Click to Show/Hide the Details
Modeling Method	EM
Publication year	2023
Closely Related Crystal Structure of This MSV
PDB ID	Scanning Method	Resolution	Mutation Sites	Details	Ref
8K7C	EM	3.9 Å	W307A	Show Detail	[1]
Structure
Expression System	Trichoplusia ni
Corresponding chain	A/B
Sequence Length	240-826		Mutation	Yes
8K7B	EM	3.9 Å	W309A	Show Detail	[1]
Structure
Expression System	Trichoplusia ni
Corresponding chain	A/B
Sequence Length	238-827		Mutation	Yes
References
1	W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol. 2023;6(1):960.

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.