Modelled Stucture
Method:Homology modeling
Teplate PDB:4XE5_A
Identity:64.902%
Minimized Score:-2634.284
Detail: Structure Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0540 Transporter Info | ||||
| Gene Name | ATP12A | ||||
| Protein Name | Potassium-transporting ATPase alpha chain 2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Cavia porcellus (Guinea pig) | |||||
| Gene Name | ATP12A | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:4XE5_A Sequence Length:998 Identity:66.333% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -2723.678 kcal/mol | |||
| Ramachandra Favored | Excellent |
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| QMEANBrane Quality | High |
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| Ramachandran Plot |
Ramz Z Score:-0.3 ±0.24 Residues in Favored Region:977 Ramachandran favored:98.09% Number of Outliers:1 Ramachandran outliers:0.10% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.81 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| References | |||||
| 1 | Structure and function of H(+)/K(+) pump mutants reveal Na(+)/K(+) pump mechanisms. Nat Commun. 2022;13(1):5270. | ||||
| 2 | An unusual conformation from Na(+)-sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na(+)-binding. Biochim Biophys Acta Mol Cell Res. 2023;1870(7):119543. | ||||
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