Modelled Stucture
Method:Homology modeling
Teplate PDB:6RTC_A
Identity:38.156%
Minimized Score:-1301.712
Detail: Structure Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0233 Transporter Info | ||||
| Gene Name | SLC26A5 | ||||
| Protein Name | Prestin | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Slc26a5 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:7CH1_A Sequence Length:700 Identity:36.649% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1791.524 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | High |
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| Ramachandran Plot |
Ramz Z Score:-0.98 ±0.3 Residues in Favored Region:680 Ramachandran favored:97.42% Number of Outliers:6 Ramachandran outliers:0.86% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.79 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Slc26a5 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure | |||||
| Click to Save PDB File in PDB Format | |||||
| Experimental Structures of This Model Oganism | |||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref |
| 5EUS | X-ray | 1.83 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | A | ||||
| Sequence Length | 505-563; 637-718 | Mutation | No | ||
| 5EUU | X-ray | 1.87 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | A | ||||
| Sequence Length | 505-563; 637-718 | Mutation | No | ||
| 5EUW | X-ray | 1.81 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | A | ||||
| Sequence Length | 505-563; 637-718 | Mutation | No | ||
| 5EUX | X-ray | 2.04 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | A | ||||
| Sequence Length | 505-563; 637-718 | Mutation | No | ||
| 5EUZ | X-ray | 2.4 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | A | ||||
| Sequence Length | 505-563; 637-718 | Mutation | No | ||
| References | |||||
| 1 | The STAS domain of mammalian SLC26A5 prestin harbours an anion-binding site. Biochem J. 2016 Feb 15;473(4):365-70. | ||||
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