General Information of Drug Transporter (DT)
DT ID	DTD0233 Transporter Info
Gene Name	SLC26A5
Transporter Name	Prestin
Gene ID	375611
UniProt ID	P58743
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	6RTC_A		Identity	38.156%
Performance	Minimized Score	-1301.712 kcal/mol
	Ramachandra Favored	Medium
	QMEANBrane Quality	High
Ramachandran Plot
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	Ramz Z Score	-0.71 ±0.34
	Residues in Favored Region	530	Ramachandran favored	96.89%
	Number of Outliers	5	Ramachandran outliers	0.91%
Local Quality
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	QMEANBrane Score		0.81
AlphaFold Protein Structure Database	P58743 Click to jump to the details page
SWISS-MODEL Database	P58743 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
7LGU	EM	2.3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	750		Mutation	No
7LGW	EM	2.7 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	750		Mutation	No
7LH2	EM	3.43 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	750		Mutation	No
7LH3	EM	4.3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	750		Mutation	No
References
1	Molecular mechanism of prestin electromotive signal amplification. Cell. 2021;184(18):4669-4679.e13.

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