Modelled Stucture
Method:Loop building
Teplate PDB:6M23_A
Identity:97.956%
Minimized Score:-2242.996
Detail: Structure Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0086 Transporter Info | ||||
| Gene Name | SLC12A5 | ||||
| Protein Name | Electroneutral potassium-chloride cotransporter 2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Slc12a5 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:7D14_A Sequence Length:1138 Identity:100% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1799.993 kcal/mol | |||
| Ramachandra Favored | Poor |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-1.35 ±0.23 Residues in Favored Region:1069 Ramachandran favored:94.10% Number of Outliers:17 Ramachandran outliers:1.50% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.72 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Slc12a5 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:7D14_A Sequence Length:1139 Identity:99.473% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1732.551 kcal/mol | |||
| Ramachandra Favored | Poor |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-1.61 ±0.23 Residues in Favored Region:1072 Ramachandran favored:94.28% Number of Outliers:13 Ramachandran outliers:1.14% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.72 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| References | |||||
| 1 | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2. Commun Biol. 2021;4(1):226. | ||||
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