Detail Information of Inter-species Structural Difference

General Information of Drug Transporter (DT)
DT ID DTD0054 Transporter Info
Gene Name ABCB8
Protein Name ATP-binding cassette sub-family B member 8
Gene ID
11194
UniProt ID
Q9NUT2
3D Structure

Modelled Stucture

Method:Loop building

Teplate PDB:5OCH_A

Identity:99.835%

Minimized Score:-1629.298

Detail: Structure Info

Inter-species Structural Differences (ISD)
Pongo abelii (Sumatran orangutan)
        Gene Name ABCB8
        UniProt ID
Q5RFQ9
        UniProt Entry
MITOS_PONAB
        3D Structure

Method:Homology modeling

Teplate PDB:7EHL_A

Sequence Length:678

Identity:98.083%

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        Performance Minimized Score -1619.025 kcal/mol
Ramachandra Favored

Medium
QMEANBrane Quality

High
        Ramachandran Plot

Ramz Z Score:-0.92 ±0.29

Residues in Favored Region:658

Ramachandran favored:97.34%

Number of Outliers:2

Ramachandran outliers:0.30%
Click to Save Ramachandran Plot in PNG Format
        Local Quality

QMEANBrane Score:0.8
Click to Save Local Quality Plot in PNG Format
Xenopus tropicalis (Western clawed frog)
        Gene Name abcb8
        UniProt ID
B2GUP8
        UniProt Entry
MITOS_XENTR
        3D Structure

Method:Homology modeling

Teplate PDB:7EHL_A

Sequence Length:632

Identity:64.319%

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        Performance Minimized Score -1518.164 kcal/mol
Ramachandra Favored

Medium
QMEANBrane Quality

High
        Ramachandran Plot

Ramz Z Score:-0.74 ±0.3

Residues in Favored Region:617

Ramachandran favored:97.94%

Number of Outliers:1

Ramachandran outliers:0.16%
Click to Save Ramachandran Plot in PNG Format
        Local Quality

QMEANBrane Score:0.8
Click to Save Local Quality Plot in PNG Format

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