Modelled Stucture
Method:Homology modeling
Teplate PDB:6UY0_A
Identity:47.93%
Minimized Score:-2889.043
Detail: Structure Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0002 Transporter Info | ||||
| Gene Name | ABCC2 | ||||
| Protein Name | Multidrug resistance-associated protein 2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Abcc2 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6UY0_A Sequence Length:1537 Identity:46.08% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -3522.531 kcal/mol | |||
| Ramachandra Favored | Excellent |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.9 ±0.19 Residues in Favored Region:1507 Ramachandran favored:98.18% Number of Outliers:6 Ramachandran outliers:0.39% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.77 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Abcc2 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6UY0_A Sequence Length:1530 Identity:46.543% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -3521.572 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.55 ±0.2 Residues in Favored Region:1495 Ramachandran favored:97.84% Number of Outliers:7 Ramachandran outliers:0.46% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.77 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Oryctolagus cuniculus (Rabbit) | |||||
| Gene Name | ABCC2 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6UY0_A Sequence Length:1525 Identity:48.031% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -3465.792 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.91 ±0.19 Residues in Favored Region:1490 Ramachandran favored:97.83% Number of Outliers:7 Ramachandran outliers:0.46% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.77 |
||||
| Click to Save Local Quality Plot in PNG Format | |||||
| References | |||||
| 1 | Structural basis for the modulation of MRP2 activity by phosphorylation and drugs. Nat Commun. 2024;15(1):1983. | ||||
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