General Information of Drug Transporter (DT)
DT ID DTD0461 Transporter Info
Gene Name SLC6A9
Protein Name Sodium- and chloride-dependent glycine transporter 1
Gene ID
6536
UniProt ID
P48067
Genetic Polymorphisms of DT (GPD)
Genetic Polymorphism rs2248829
Site of GPD chr1:44002563 (GRCh38.p12)
GPD Type SNP
Allele(s) in dbSNP G>A
Minor Allele Frequency G=0.8290/1640 (Global)
 Allele G Click to Show/Hide the Full List of Affected Drugs:           1 Drugs in Total
Methamphetamine N.A. Substance-related Disorders Allele G is associated with increased risk of Substance-Related Disorders due to methamphetamine as compared to allele A. [ 1]
Genetic Polymorphism rs2486001
Site of GPD chr1:44010315 (GRCh38.p12)
GPD Type SNP
Allele(s) in dbSNP T>C
Minor Allele Frequency T=0.1590/314 (Global)
 Allele T Click to Show/Hide the Full List of Affected Drugs:           1 Drugs in Total
Methamphetamine N.A. Substance-related Disorders Allele T is associated with increased risk of Substance-Related Disorders due to methamphetamine as compared to allele C. [ 1]
References
1 The glycine transporter 1 gene (GLYT1) is associated with methamphetamine-use disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 05;147B(1):54-8.

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