General Information of Drug Transporter (DT)
DT ID	DTD0188 Transporter Info
Gene Name	SLC25A27
Protein Name	Mitochondrial uncoupling protein 4
Gene ID	9481
UniProt ID	O95847
Genetic Polymorphisms of DT (GPD)
Genetic Polymorphism	rs2270450
Site of GPD	chr6:46677138 (GRCh38.p12)
GPD Type	SNP
Allele(s) in dbSNP	C>T
Minor Allele Frequency	C=0.6850/1355 (Global)
Allele T	Click to Show/Hide the Full List of Affected Drugs:           1 Drugs in Total
Antipsychotics	N.A.	Diarrhea	Allele T is not associated with ultra-resistance when treated with antipsychotics in people with Schizophrenia as compared to allele C.		[ 1]
Genetic Polymorphism	rs9395206
Site of GPD	chr6:46670685 (GRCh38.p12)
GPD Type	SNP
Allele(s) in dbSNP	T>A / T>C / T>G
Minor Allele Frequency	T=0.1170/231 (Global)
Allele T	Click to Show/Hide the Full List of Affected Drugs:           1 Drugs in Total
Antipsychotics	N.A.	Diarrhea	Allele T is not associated with ultra-resistance when treated with antipsychotics in people with Schizophrenia as compared to allele A.		[ 1]
References
1	Association of an UCP4 (SLC25A27) haplotype with ultra-resistant schizophrenia. Pharmacogenomics. 2011 Feb;12(2):185-93.

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