Detail Information of Genetic Polymorphisms
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0165 Transporter Info | ||||
| Gene Name | SLC24A4 | ||||
| Protein Name | Sodium/potassium/calcium exchanger 4 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Genetic Polymorphisms of DT (GPD) | |||||
| Genetic Polymorphism | rs77441273 | ||||
| Site of GPD | chr14:92493513 (GRCh38.p12) | ||||
| GPD Type | SNP | ||||
| Allele(s) in dbSNP | G>A | ||||
| Minor Allele Frequency | G=0.9950/1969 (Global) | ||||
| Genotype AG | Click to Show/Hide the Full List of Affected Drugs: 1 Drugs in Total | ||||
| Salbutamol | N.A. | Gastrointestinal Stromal Tumors | Genotype AG is associated with increased response to salbutamol in children with Asthma as compared to genotype GG. | [ 1] | |
| References | |||||
| 1 | A genome-wide association study of bronchodilator response in Latinos implicates rare variants. J Allergy Clin Immunol. 2014 Feb;133(2):370-8. | ||||
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