Detail Information of Epigenetic Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0443 Transporter Info
Gene Name	SLC6A11
Transporter Name	Sodium- and chloride-dependent GABA transporter 3
Gene ID	6538
UniProt ID	P48066

Epigenetic Regulations of This DT (EGR)
Methylation
Pancretic ductal adenocarcinoma	13 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	5'UTR (cg25320780)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.28E+00	Statistic Test	p-value:3.84E-07; Z-score:-1.63E+00
Methylation in Case	4.73E-01 (Median)	Methylation in Control	6.05E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	5'UTR (cg17537007)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:1.03E-04; Z-score:-3.48E-01
Methylation in Case	8.62E-01 (Median)	Methylation in Control	8.74E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	5'UTR (cg20208384)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.13E+00	Statistic Test	p-value:6.92E-03; Z-score:-7.53E-01
Methylation in Case	1.30E-01 (Median)	Methylation in Control	1.46E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	TSS1500 (cg06808585)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.92E+00	Statistic Test	p-value:1.80E-11; Z-score:-2.19E+00
Methylation in Case	2.38E-01 (Median)	Methylation in Control	4.57E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	TSS1500 (cg24237813)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.08E+00	Statistic Test	p-value:1.25E-04; Z-score:-1.10E+00
Methylation in Case	3.59E-01 (Median)	Methylation in Control	3.86E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	TSS200 (cg07808555)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:3.34E+00	Statistic Test	p-value:5.63E-44; Z-score:6.78E+00
Methylation in Case	3.92E-01 (Median)	Methylation in Control	1.17E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	TSS200 (cg13432451)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.11E+00	Statistic Test	p-value:3.10E-08; Z-score:3.82E-01
Methylation in Case	6.73E-02 (Median)	Methylation in Control	6.05E-02 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	TSS200 (cg21080921)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.17E+00	Statistic Test	p-value:4.15E-05; Z-score:-8.06E-01
Methylation in Case	4.55E-01 (Median)	Methylation in Control	5.32E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	1stExon (cg02854695)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.96E+00	Statistic Test	p-value:1.08E-16; Z-score:1.37E+00
Methylation in Case	1.24E-01 (Median)	Methylation in Control	6.33E-02 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg18597991)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.15E+00	Statistic Test	p-value:5.93E-09; Z-score:-1.67E+00
Methylation in Case	7.25E-01 (Median)	Methylation in Control	8.35E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg13459035)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.13E+00	Statistic Test	p-value:7.66E-07; Z-score:-1.48E+00
Methylation in Case	6.18E-01 (Median)	Methylation in Control	7.00E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg18886814)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.05E+00	Statistic Test	p-value:2.10E-03; Z-score:-8.54E-01
Methylation in Case	4.96E-01 (Median)	Methylation in Control	5.19E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC6A11 in pancretic ductal adenocarcinoma			[ 1 ]
Location	3'UTR (cg26960896)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.26E+00	Statistic Test	p-value:1.85E-07; Z-score:-2.08E+00
Methylation in Case	2.78E-01 (Median)	Methylation in Control	3.51E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Bladder cancer	4 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in bladder cancer			[ 2 ]
Location	TSS1500 (cg09395732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.27E+00	Statistic Test	p-value:9.06E-06; Z-score:-8.57E+00
Methylation in Case	6.15E-01 (Median)	Methylation in Control	7.79E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in bladder cancer			[ 2 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.23E+00	Statistic Test	p-value:1.94E-03; Z-score:-5.10E+00
Methylation in Case	5.96E-01 (Median)	Methylation in Control	7.34E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in bladder cancer			[ 2 ]
Location	Body (cg04746240)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:1.54E-02; Z-score:-9.76E-01
Methylation in Case	8.76E-01 (Median)	Methylation in Control	8.91E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in bladder cancer			[ 2 ]
Location	Body (cg15284635)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.18E+00	Statistic Test	p-value:3.97E-02; Z-score:2.40E+00
Methylation in Case	4.28E-01 (Median)	Methylation in Control	3.62E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Breast cancer	15 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.56E+00	Statistic Test	p-value:2.34E-08; Z-score:1.54E+00
Methylation in Case	1.99E-01 (Median)	Methylation in Control	1.28E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS1500 (cg09395732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.06E+00	Statistic Test	p-value:5.07E-08; Z-score:-1.65E+00
Methylation in Case	7.81E-01 (Median)	Methylation in Control	8.25E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.65E+00	Statistic Test	p-value:2.91E-06; Z-score:1.36E+00
Methylation in Case	1.09E-01 (Median)	Methylation in Control	6.57E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.19E+00	Statistic Test	p-value:9.90E-05; Z-score:7.17E-01
Methylation in Case	1.31E-01 (Median)	Methylation in Control	1.10E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.63E+00	Statistic Test	p-value:6.28E-08; Z-score:1.52E+00
Methylation in Case	2.63E-01 (Median)	Methylation in Control	1.61E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.36E+00	Statistic Test	p-value:1.40E-05; Z-score:8.51E-01
Methylation in Case	2.47E-01 (Median)	Methylation in Control	1.82E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.14E+00	Statistic Test	p-value:7.94E-04; Z-score:5.06E-01
Methylation in Case	1.42E-01 (Median)	Methylation in Control	1.25E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS200 (cg10527010)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.37E+00	Statistic Test	p-value:1.42E-03; Z-score:6.14E-01
Methylation in Case	1.08E-01 (Median)	Methylation in Control	7.88E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	TSS200 (cg09022422)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.25E+00	Statistic Test	p-value:2.13E-02; Z-score:2.27E-01
Methylation in Case	5.09E-02 (Median)	Methylation in Control	4.07E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.09E+00	Statistic Test	p-value:1.58E-03; Z-score:1.48E-01
Methylation in Case	3.92E-02 (Median)	Methylation in Control	3.59E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.18E+00	Statistic Test	p-value:3.74E-07; Z-score:-1.65E+00
Methylation in Case	5.94E-01 (Median)	Methylation in Control	7.03E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.21E+00	Statistic Test	p-value:2.56E-05; Z-score:7.64E-01
Methylation in Case	2.83E-01 (Median)	Methylation in Control	2.34E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	Body (cg14788003)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.18E+00	Statistic Test	p-value:5.05E-05; Z-score:-8.54E-01
Methylation in Case	6.36E-01 (Median)	Methylation in Control	7.50E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon14	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	Body (cg04746240)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:7.34E-05; Z-score:-1.06E+00
Methylation in Case	8.69E-01 (Median)	Methylation in Control	8.85E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon15	Methylation of SLC6A11 in breast cancer			[ 3 ]
Location	Body (cg15668533)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.08E+00	Statistic Test	p-value:1.03E-02; Z-score:4.20E-01
Methylation in Case	2.86E-01 (Median)	Methylation in Control	2.66E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Celiac disease	2 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in celiac disease			[ 4 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.60E+00	Statistic Test	p-value:2.72E-02; Z-score:9.83E-01
Methylation in Case	9.16E-02 (Median)	Methylation in Control	5.74E-02 (Median)
Studied Phenotype	Celiac disease[ ICD-11:DA95]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in celiac disease			[ 4 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.12E+00	Statistic Test	p-value:3.42E-02; Z-score:-8.49E-01
Methylation in Case	6.99E-01 (Median)	Methylation in Control	7.83E-01 (Median)
Studied Phenotype	Celiac disease[ ICD-11:DA95]
Experimental Material	Patient tissue samples
Renal cell carcinoma	12 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.52E+00	Statistic Test	p-value:2.70E-07; Z-score:2.00E+00
Methylation in Case	1.25E-01 (Median)	Methylation in Control	4.98E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.70E+00	Statistic Test	p-value:6.98E-07; Z-score:1.77E+00
Methylation in Case	1.49E-01 (Median)	Methylation in Control	8.75E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.67E+00	Statistic Test	p-value:1.78E-05; Z-score:1.16E+00
Methylation in Case	9.88E-02 (Median)	Methylation in Control	5.91E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS1500 (cg09395732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.07E+00	Statistic Test	p-value:2.08E-02; Z-score:1.02E+00
Methylation in Case	9.24E-01 (Median)	Methylation in Control	8.66E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.86E+00	Statistic Test	p-value:2.81E-13; Z-score:2.77E+00
Methylation in Case	3.78E-01 (Median)	Methylation in Control	2.03E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.14E+00	Statistic Test	p-value:1.13E-12; Z-score:2.68E+00
Methylation in Case	3.84E-01 (Median)	Methylation in Control	1.80E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.49E+00	Statistic Test	p-value:7.91E-04; Z-score:9.08E-01
Methylation in Case	1.21E-01 (Median)	Methylation in Control	8.15E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS200 (cg10527010)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.38E+00	Statistic Test	p-value:4.51E-03; Z-score:6.35E-01
Methylation in Case	8.19E-02 (Median)	Methylation in Control	5.91E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	TSS200 (cg09022422)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.43E+00	Statistic Test	p-value:1.40E-02; Z-score:3.78E-01
Methylation in Case	3.46E-02 (Median)	Methylation in Control	2.42E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.08E+00	Statistic Test	p-value:5.17E-04; Z-score:1.20E+00
Methylation in Case	5.08E-02 (Median)	Methylation in Control	2.44E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.63E+00	Statistic Test	p-value:2.11E-06; Z-score:1.94E+00
Methylation in Case	2.33E-01 (Median)	Methylation in Control	1.43E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in clear cell renal cell carcinoma			[ 5 ]
Location	Body (cg15668533)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.20E+00	Statistic Test	p-value:5.81E-04; Z-score:8.89E-01
Methylation in Case	2.53E-01 (Median)	Methylation in Control	2.11E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Colon cancer	12 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	TSS1500 (cg15081220)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.81E+00	Statistic Test	p-value:2.34E-06; Z-score:4.63E+00
Methylation in Case	6.79E-01 (Median)	Methylation in Control	3.76E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	TSS1500 (cg25804018)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.04E+00	Statistic Test	p-value:7.04E-04; Z-score:4.78E+00
Methylation in Case	1.52E-01 (Median)	Methylation in Control	7.46E-02 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	TSS200 (cg04285869)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.15E+00	Statistic Test	p-value:1.30E-04; Z-score:-2.24E+00
Methylation in Case	5.79E-01 (Median)	Methylation in Control	6.65E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	1stExon (cg24415208)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.31E+00	Statistic Test	p-value:6.78E-07; Z-score:1.85E+00
Methylation in Case	6.74E-01 (Median)	Methylation in Control	5.16E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	1stExon (cg10671668)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.93E+00	Statistic Test	p-value:1.11E-05; Z-score:2.87E+00
Methylation in Case	6.21E-01 (Median)	Methylation in Control	3.21E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	Body (cg18705155)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.68E+00	Statistic Test	p-value:4.69E-09; Z-score:-3.79E+00
Methylation in Case	3.76E-01 (Median)	Methylation in Control	6.29E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	Body (cg18677871)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.11E+00	Statistic Test	p-value:7.05E-09; Z-score:1.66E+00
Methylation in Case	6.61E-01 (Median)	Methylation in Control	5.95E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	Body (cg14224444)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.41E+00	Statistic Test	p-value:1.07E-06; Z-score:-2.32E+00
Methylation in Case	4.23E-01 (Median)	Methylation in Control	5.99E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	Body (cg26890189)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.20E+00	Statistic Test	p-value:1.18E-04; Z-score:1.33E+00
Methylation in Case	5.32E-01 (Median)	Methylation in Control	4.45E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	Body (cg17864405)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.07E+00	Statistic Test	p-value:2.11E-03; Z-score:-1.18E+00
Methylation in Case	7.39E-01 (Median)	Methylation in Control	7.94E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	3'UTR (cg07501827)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.13E+00	Statistic Test	p-value:1.57E-04; Z-score:-1.65E+00
Methylation in Case	5.97E-01 (Median)	Methylation in Control	6.73E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in colon adenocarcinoma			[ 6 ]
Location	3'UTR (cg06566678)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:3.04E-03; Z-score:-7.76E-01
Methylation in Case	8.21E-01 (Median)	Methylation in Control	8.36E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Colorectal cancer	15 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.01E+00	Statistic Test	p-value:2.22E-13; Z-score:2.93E+00
Methylation in Case	5.50E-01 (Median)	Methylation in Control	2.74E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.81E+00	Statistic Test	p-value:8.18E-12; Z-score:2.61E+00
Methylation in Case	5.84E-01 (Median)	Methylation in Control	3.23E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.55E+00	Statistic Test	p-value:5.91E-11; Z-score:2.52E+00
Methylation in Case	6.57E-01 (Median)	Methylation in Control	4.25E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS1500 (cg09395732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:3.76E-03; Z-score:-3.71E-01
Methylation in Case	9.03E-01 (Median)	Methylation in Control	9.09E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS200 (cg09022422)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.61E+00	Statistic Test	p-value:4.23E-18; Z-score:3.70E+00
Methylation in Case	4.23E-01 (Median)	Methylation in Control	1.62E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS200 (cg10527010)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.03E+00	Statistic Test	p-value:3.67E-14; Z-score:3.01E+00
Methylation in Case	4.95E-01 (Median)	Methylation in Control	2.44E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.59E+00	Statistic Test	p-value:6.47E-12; Z-score:2.53E+00
Methylation in Case	6.77E-01 (Median)	Methylation in Control	4.25E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.33E+00	Statistic Test	p-value:1.28E-06; Z-score:1.40E+00
Methylation in Case	6.10E-01 (Median)	Methylation in Control	4.60E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.35E+00	Statistic Test	p-value:2.67E-06; Z-score:1.41E+00
Methylation in Case	6.21E-01 (Median)	Methylation in Control	4.62E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:3.36E+00	Statistic Test	p-value:6.46E-18; Z-score:4.43E+00
Methylation in Case	4.10E-01 (Median)	Methylation in Control	1.22E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.35E+00	Statistic Test	p-value:2.67E-15; Z-score:-7.44E+00
Methylation in Case	5.81E-01 (Median)	Methylation in Control	7.87E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	Body (cg14788003)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.22E+00	Statistic Test	p-value:2.19E-14; Z-score:-5.71E+00
Methylation in Case	6.95E-01 (Median)	Methylation in Control	8.50E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.31E+00	Statistic Test	p-value:2.90E-05; Z-score:1.27E+00
Methylation in Case	6.03E-01 (Median)	Methylation in Control	4.59E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon14	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	Body (cg15668533)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.16E+00	Statistic Test	p-value:1.49E-03; Z-score:9.24E-01
Methylation in Case	6.80E-01 (Median)	Methylation in Control	5.86E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon15	Methylation of SLC6A11 in colorectal cancer			[ 7 ]
Location	Body (cg04746240)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.00E+00	Statistic Test	p-value:1.10E-02; Z-score:-4.73E-01
Methylation in Case	9.49E-01 (Median)	Methylation in Control	9.52E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Hepatocellular carcinoma	23 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS1500 (cg26622895)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.63E+00	Statistic Test	p-value:1.20E-17; Z-score:-3.79E+00
Methylation in Case	4.03E-01 (Median)	Methylation in Control	6.56E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS1500 (cg02505749)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:5.24E+00	Statistic Test	p-value:4.59E-16; Z-score:6.77E+00
Methylation in Case	3.51E-01 (Median)	Methylation in Control	6.69E-02 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.93E+00	Statistic Test	p-value:1.75E-07; Z-score:3.70E+00
Methylation in Case	2.95E-01 (Median)	Methylation in Control	1.53E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS1500 (cg09395732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:4.30E-06; Z-score:-7.24E-01
Methylation in Case	7.97E-01 (Median)	Methylation in Control	8.15E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.60E+00	Statistic Test	p-value:4.56E-06; Z-score:2.68E+00
Methylation in Case	2.94E-01 (Median)	Methylation in Control	1.84E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.32E+00	Statistic Test	p-value:3.73E-05; Z-score:1.78E+00
Methylation in Case	1.90E-01 (Median)	Methylation in Control	1.45E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.29E+00	Statistic Test	p-value:6.81E-09; Z-score:5.69E+00
Methylation in Case	3.78E-01 (Median)	Methylation in Control	1.65E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.49E+00	Statistic Test	p-value:5.68E-05; Z-score:2.39E+00
Methylation in Case	4.84E-01 (Median)	Methylation in Control	3.25E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.40E+00	Statistic Test	p-value:1.74E-04; Z-score:2.27E+00
Methylation in Case	4.86E-01 (Median)	Methylation in Control	3.48E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	1stExon (cg07830847)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.60E+00	Statistic Test	p-value:4.04E-17; Z-score:-1.27E+01
Methylation in Case	5.34E-01 (Median)	Methylation in Control	8.55E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg07765706)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-2.21E+00	Statistic Test	p-value:2.64E-20; Z-score:-2.24E+01
Methylation in Case	4.31E-01 (Median)	Methylation in Control	9.54E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg14404146)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.20E+00	Statistic Test	p-value:3.31E-20; Z-score:-8.29E+00
Methylation in Case	7.64E-01 (Median)	Methylation in Control	9.20E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg09355292)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.58E+00	Statistic Test	p-value:9.13E-20; Z-score:-7.30E+00
Methylation in Case	5.06E-01 (Median)	Methylation in Control	8.01E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon14	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg17864405)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.34E+00	Statistic Test	p-value:1.76E-17; Z-score:-4.72E+00
Methylation in Case	5.96E-01 (Median)	Methylation in Control	8.01E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon15	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg00704369)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.73E+00	Statistic Test	p-value:1.21E-16; Z-score:-2.65E+00
Methylation in Case	3.63E-01 (Median)	Methylation in Control	6.27E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon16	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg00309313)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.52E+00	Statistic Test	p-value:2.20E-15; Z-score:-6.55E+00
Methylation in Case	4.85E-01 (Median)	Methylation in Control	7.35E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon17	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg08903425)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.52E+00	Statistic Test	p-value:4.61E-15; Z-score:-1.68E+00
Methylation in Case	1.98E-01 (Median)	Methylation in Control	3.02E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon18	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg14788003)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.15E+00	Statistic Test	p-value:2.30E-08; Z-score:-2.44E+00
Methylation in Case	6.19E-01 (Median)	Methylation in Control	7.13E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon19	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.16E+00	Statistic Test	p-value:2.52E-06; Z-score:-1.68E+00
Methylation in Case	5.69E-01 (Median)	Methylation in Control	6.60E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon20	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg15284635)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.20E+00	Statistic Test	p-value:7.03E-06; Z-score:-1.59E+00
Methylation in Case	4.26E-01 (Median)	Methylation in Control	5.13E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon21	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.37E+00	Statistic Test	p-value:7.06E-05; Z-score:2.61E+00
Methylation in Case	4.39E-01 (Median)	Methylation in Control	3.21E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon22	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	Body (cg04746240)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:3.27E-04; Z-score:-9.05E-01
Methylation in Case	8.61E-01 (Median)	Methylation in Control	8.73E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon23	Methylation of SLC6A11 in hepatocellular carcinoma			[ 8 ]
Location	3'UTR (cg20495476)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.56E+00	Statistic Test	p-value:3.27E-16; Z-score:-4.73E+00
Methylation in Case	4.18E-01 (Median)	Methylation in Control	6.50E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
HIV infection	14 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.57E+00	Statistic Test	p-value:3.75E-06; Z-score:2.22E+00
Methylation in Case	1.81E-01 (Median)	Methylation in Control	1.15E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.37E+00	Statistic Test	p-value:4.51E-06; Z-score:2.16E+00
Methylation in Case	2.55E-01 (Median)	Methylation in Control	1.86E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.26E+00	Statistic Test	p-value:3.15E-04; Z-score:1.10E+00
Methylation in Case	1.73E-01 (Median)	Methylation in Control	1.37E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.39E+00	Statistic Test	p-value:1.07E-07; Z-score:2.53E+00
Methylation in Case	4.19E-01 (Median)	Methylation in Control	3.02E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.51E+00	Statistic Test	p-value:1.12E-07; Z-score:2.58E+00
Methylation in Case	3.97E-01 (Median)	Methylation in Control	2.63E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS200 (cg10527010)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.93E+00	Statistic Test	p-value:1.18E-04; Z-score:1.87E+00
Methylation in Case	1.32E-01 (Median)	Methylation in Control	6.82E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.37E+00	Statistic Test	p-value:1.39E-04; Z-score:1.10E+00
Methylation in Case	1.72E-01 (Median)	Methylation in Control	1.25E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	TSS200 (cg09022422)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:3.06E+00	Statistic Test	p-value:2.50E-04; Z-score:1.69E+00
Methylation in Case	7.50E-02 (Median)	Methylation in Control	2.45E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.37E+00	Statistic Test	p-value:6.99E-06; Z-score:2.87E+00
Methylation in Case	1.00E-01 (Median)	Methylation in Control	4.23E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.34E+00	Statistic Test	p-value:1.60E-06; Z-score:1.64E+00
Methylation in Case	3.05E-01 (Median)	Methylation in Control	2.28E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	Body (cg14788003)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.10E+00	Statistic Test	p-value:6.04E-06; Z-score:1.49E+00
Methylation in Case	6.90E-01 (Median)	Methylation in Control	6.26E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.12E+00	Statistic Test	p-value:2.07E-05; Z-score:-1.98E+00
Methylation in Case	7.39E-01 (Median)	Methylation in Control	8.28E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	Body (cg15668533)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.23E+00	Statistic Test	p-value:1.54E-03; Z-score:1.35E+00
Methylation in Case	3.10E-01 (Median)	Methylation in Control	2.51E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon14	Methylation of SLC6A11 in HIV infection			[ 9 ]
Location	Body (cg15284635)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.04E+00	Statistic Test	p-value:2.23E-02; Z-score:3.43E-01
Methylation in Case	5.39E-01 (Median)	Methylation in Control	5.19E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Lung adenocarcinoma	11 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS1500 (cg00605982)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.76E+00	Statistic Test	p-value:5.24E-03; Z-score:4.59E+00
Methylation in Case	2.85E-01 (Median)	Methylation in Control	1.62E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.83E+00	Statistic Test	p-value:5.96E-03; Z-score:7.57E+00
Methylation in Case	3.57E-01 (Median)	Methylation in Control	1.95E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.01E+00	Statistic Test	p-value:7.64E-03; Z-score:6.11E+00
Methylation in Case	3.27E-01 (Median)	Methylation in Control	1.62E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.56E+00	Statistic Test	p-value:2.28E-03; Z-score:4.18E+00
Methylation in Case	4.86E-01 (Median)	Methylation in Control	3.12E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.63E+00	Statistic Test	p-value:2.59E-03; Z-score:3.60E+00
Methylation in Case	4.98E-01 (Median)	Methylation in Control	3.06E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.72E+00	Statistic Test	p-value:4.86E-03; Z-score:3.83E+00
Methylation in Case	3.38E-01 (Median)	Methylation in Control	1.96E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS200 (cg10527010)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.11E+00	Statistic Test	p-value:7.37E-03; Z-score:4.56E+00
Methylation in Case	2.49E-01 (Median)	Methylation in Control	1.18E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	TSS200 (cg09022422)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.63E+00	Statistic Test	p-value:1.06E-02; Z-score:4.73E+00
Methylation in Case	2.10E-01 (Median)	Methylation in Control	7.99E-02 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.07E+00	Statistic Test	p-value:9.47E-03; Z-score:6.22E+00
Methylation in Case	2.12E-01 (Median)	Methylation in Control	1.03E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.67E+00	Statistic Test	p-value:2.36E-03; Z-score:2.57E+00
Methylation in Case	4.18E-01 (Median)	Methylation in Control	2.50E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC6A11 in lung adenocarcinoma			[ 10 ]
Location	Body (cg15668533)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.55E+00	Statistic Test	p-value:6.64E-03; Z-score:2.37E+00
Methylation in Case	4.15E-01 (Median)	Methylation in Control	2.67E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Papillary thyroid cancer	10 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	TSS1500 (cg18290624)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.12E+00	Statistic Test	p-value:7.46E-04; Z-score:6.70E-01
Methylation in Case	1.87E-01 (Median)	Methylation in Control	1.67E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	TSS1500 (cg07744841)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.22E+00	Statistic Test	p-value:8.15E-03; Z-score:6.12E-01
Methylation in Case	1.29E-01 (Median)	Methylation in Control	1.06E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	TSS200 (cg21123160)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.54E+00	Statistic Test	p-value:2.61E-05; Z-score:1.22E+00
Methylation in Case	2.50E-01 (Median)	Methylation in Control	1.63E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.25E+00	Statistic Test	p-value:9.30E-05; Z-score:8.34E-01
Methylation in Case	2.52E-01 (Median)	Methylation in Control	2.02E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	TSS200 (cg09022422)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.09E+00	Statistic Test	p-value:3.08E-02; Z-score:2.24E-01
Methylation in Case	7.12E-02 (Median)	Methylation in Control	6.54E-02 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.13E+00	Statistic Test	p-value:2.16E-03; Z-score:3.86E-01
Methylation in Case	8.04E-02 (Median)	Methylation in Control	7.14E-02 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.14E+00	Statistic Test	p-value:2.97E-09; Z-score:-1.79E+00
Methylation in Case	7.06E-01 (Median)	Methylation in Control	8.06E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.13E+00	Statistic Test	p-value:1.18E-02; Z-score:4.02E-01
Methylation in Case	1.92E-01 (Median)	Methylation in Control	1.71E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg14788003)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.03E+00	Statistic Test	p-value:1.24E-02; Z-score:-3.53E-01
Methylation in Case	7.52E-01 (Median)	Methylation in Control	7.71E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC6A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg04746240)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:3.48E-02; Z-score:-6.07E-01
Methylation in Case	9.39E-01 (Median)	Methylation in Control	9.46E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Prostate cancer	2 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in prostate cancer			[ 12 ]
Location	TSS1500 (cg04139184)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.25E+00	Statistic Test	p-value:4.38E-02; Z-score:1.76E+00
Methylation in Case	8.39E-01 (Median)	Methylation in Control	6.73E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in prostate cancer			[ 12 ]
Location	Body (cg01021245)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.04E+00	Statistic Test	p-value:4.96E-02; Z-score:1.35E+00
Methylation in Case	9.30E-01 (Median)	Methylation in Control	8.91E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Panic disorder	3 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in panic disorder			[ 13 ]
Location	TSS200 (cg26836233)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-9.48E-01	Statistic Test	p-value:7.94E-03; Z-score:-3.22E-01
Methylation in Case	-3.65E+00 (Median)	Methylation in Control	-3.46E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in panic disorder			[ 13 ]
Location	TSS200 (cg10527010)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-9.51E-01	Statistic Test	p-value:2.63E-02; Z-score:-2.96E-01
Methylation in Case	-4.84E+00 (Median)	Methylation in Control	-4.60E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in panic disorder			[ 13 ]
Location	TSS200 (cg22331862)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-8.89E-01	Statistic Test	p-value:4.89E-02; Z-score:-4.67E-01
Methylation in Case	-1.65E+00 (Median)	Methylation in Control	-1.47E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Atypical teratoid rhabdoid tumor	4 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in atypical teratoid rhabdoid tumor			[ 14 ]
Location	1stExon (cg16435571)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.37E+00	Statistic Test	p-value:5.20E-18; Z-score:-2.48E+00
Methylation in Case	5.77E-01 (Median)	Methylation in Control	7.93E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC6A11 in atypical teratoid rhabdoid tumor			[ 14 ]
Location	Body (cg04746240)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.12E+00	Statistic Test	p-value:9.39E-04; Z-score:6.33E-01
Methylation in Case	8.77E-01 (Median)	Methylation in Control	7.80E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC6A11 in atypical teratoid rhabdoid tumor			[ 14 ]
Location	Body (cg09660365)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.54E+00	Statistic Test	p-value:1.16E-02; Z-score:-3.32E-01
Methylation in Case	7.06E-02 (Median)	Methylation in Control	1.09E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC6A11 in atypical teratoid rhabdoid tumor			[ 14 ]
Location	Body (cg12461092)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:2.78E-02; Z-score:-2.44E-01
Methylation in Case	8.52E-01 (Median)	Methylation in Control	8.58E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Depression	1 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC6A11 in depression			[ 15 ]
Location	Body (cg15668533)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.12E+00	Statistic Test	p-value:4.07E-02; Z-score:6.58E-01
Methylation in Case	2.06E-01 (Median)	Methylation in Control	1.84E-01 (Median)
Studied Phenotype	Depression[ ICD-11:6A8Z]
Experimental Material	Patient tissue samples

References
1	Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
2	DNA Methylation Dynamics in Urological Tumors.
3	Genome-wide Scan for Methylation Profiles in Breast Cancer
4	The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region. Mol Ther Oncolytics. 2019 Feb 5;12:235-245.
5	A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
6	Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.
7	Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
8	Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
9	HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15;212(10):1563-73.
10	DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
11	Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
12	Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.
13	DNA Methylation signatures in panic disorder. Transl Psychiatry. 2017 Dec 18;7(12):1287.
14	Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell. 2016 Mar 14;29(3):379-393.
15	DNA methylation and inflammation marker profiles associated with a history of depression. Hum Mol Genet. 2018 Aug 15;27(16):2840-2850.

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