Detail Information of Epigenetic Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0102 Transporter Info
Gene Name	SLC16A11
Transporter Name	Monocarboxylate transporter 11
Gene ID	162515
UniProt ID	Q8NCK7

Epigenetic Regulations of This DT (EGR)
Methylation
Colon cancer	7 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	5'UTR (cg18353345)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.24E+00	Statistic Test	p-value:1.84E-03; Z-score:-1.25E+00
Methylation in Case	9.45E-02 (Median)	Methylation in Control	1.17E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	TSS200 (cg04913974)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.23E+00	Statistic Test	p-value:2.37E-04; Z-score:-2.50E+00
Methylation in Case	4.50E-01 (Median)	Methylation in Control	5.56E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	1stExon (cg26923754)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.06E+00	Statistic Test	p-value:3.43E-03; Z-score:-9.57E-01
Methylation in Case	5.05E-01 (Median)	Methylation in Control	5.37E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	Body (cg04569615)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.13E+00	Statistic Test	p-value:1.13E-03; Z-score:9.77E-01
Methylation in Case	6.93E-01 (Median)	Methylation in Control	6.11E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	Body (cg19130824)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.04E+00	Statistic Test	p-value:1.40E-03; Z-score:7.47E-01
Methylation in Case	7.77E-01 (Median)	Methylation in Control	7.46E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	Body (cg14808360)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.02E+00	Statistic Test	p-value:3.66E-03; Z-score:8.33E-01
Methylation in Case	9.04E-01 (Median)	Methylation in Control	8.87E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in colon adenocarcinoma			[ 1 ]
Location	3'UTR (cg00630480)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.13E+00	Statistic Test	p-value:1.99E-03; Z-score:-1.63E+00
Methylation in Case	5.73E-01 (Median)	Methylation in Control	6.48E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Bladder cancer	9 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	TSS1500 (cg21090344)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-3.03E+00	Statistic Test	p-value:8.38E-09; Z-score:-8.53E+00
Methylation in Case	1.69E-01 (Median)	Methylation in Control	5.12E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	TSS1500 (cg14950751)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.47E+00	Statistic Test	p-value:2.58E-05; Z-score:-3.68E+00
Methylation in Case	2.29E-01 (Median)	Methylation in Control	3.37E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	TSS1500 (cg16374411)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.47E+00	Statistic Test	p-value:7.47E-04; Z-score:-3.92E+00
Methylation in Case	1.83E-01 (Median)	Methylation in Control	2.70E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	TSS200 (cg13181928)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.48E+00	Statistic Test	p-value:2.91E-03; Z-score:-2.72E+00
Methylation in Case	1.12E-01 (Median)	Methylation in Control	1.66E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	TSS200 (cg07011163)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.22E+00	Statistic Test	p-value:2.93E-02; Z-score:-1.28E+00
Methylation in Case	1.09E-01 (Median)	Methylation in Control	1.33E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	TSS200 (cg03892045)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.75E+00	Statistic Test	p-value:4.01E-02; Z-score:-1.66E+00
Methylation in Case	5.71E-02 (Median)	Methylation in Control	1.00E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	Body (cg05031424)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.29E+00	Statistic Test	p-value:1.13E-05; Z-score:-3.21E+00
Methylation in Case	5.02E-01 (Median)	Methylation in Control	6.50E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	Body (cg03096732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.44E+00	Statistic Test	p-value:2.31E-05; Z-score:-4.23E+00
Methylation in Case	1.19E-01 (Median)	Methylation in Control	1.71E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC16A11 in bladder cancer			[ 2 ]
Location	Body (cg18736141)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.53E+00	Statistic Test	p-value:5.70E-03; Z-score:-2.23E+00
Methylation in Case	1.18E-01 (Median)	Methylation in Control	1.81E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Breast cancer	13 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS1500 (cg21090344)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.09E+00	Statistic Test	p-value:1.87E-03; Z-score:-5.87E-01
Methylation in Case	5.76E-01 (Median)	Methylation in Control	6.29E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS1500 (cg16374411)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.10E+00	Statistic Test	p-value:1.33E-02; Z-score:9.06E-01
Methylation in Case	2.96E-01 (Median)	Methylation in Control	2.68E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS200 (cg07011163)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.42E+00	Statistic Test	p-value:5.08E-06; Z-score:2.04E+00
Methylation in Case	1.42E-01 (Median)	Methylation in Control	9.97E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS200 (cg13181928)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.45E+00	Statistic Test	p-value:1.16E-05; Z-score:1.99E+00
Methylation in Case	1.68E-01 (Median)	Methylation in Control	1.16E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS200 (cg03892045)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.44E+00	Statistic Test	p-value:8.00E-05; Z-score:1.21E+00
Methylation in Case	8.67E-02 (Median)	Methylation in Control	6.01E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS200 (cg08352268)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.18E+00	Statistic Test	p-value:1.77E-03; Z-score:8.79E-01
Methylation in Case	1.13E-01 (Median)	Methylation in Control	9.58E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS200 (cg03712541)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.41E+00	Statistic Test	p-value:3.75E-03; Z-score:5.92E-01
Methylation in Case	5.01E-02 (Median)	Methylation in Control	3.54E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	TSS200 (cg18530716)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.18E+00	Statistic Test	p-value:7.36E-03; Z-score:5.81E-01
Methylation in Case	1.00E-01 (Median)	Methylation in Control	8.49E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	Body (cg02489908)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.21E+00	Statistic Test	p-value:1.76E-06; Z-score:1.97E+00
Methylation in Case	3.54E-01 (Median)	Methylation in Control	2.92E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	Body (cg18736141)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.11E+00	Statistic Test	p-value:1.05E-03; Z-score:6.15E-01
Methylation in Case	2.04E-01 (Median)	Methylation in Control	1.83E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	Body (cg01019875)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.05E+00	Statistic Test	p-value:3.23E-02; Z-score:1.61E-01
Methylation in Case	1.80E-01 (Median)	Methylation in Control	1.72E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	Body (cg03096732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.21E+00	Statistic Test	p-value:3.83E-02; Z-score:-1.36E+00
Methylation in Case	1.40E-01 (Median)	Methylation in Control	1.70E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC16A11 in breast cancer			[ 3 ]
Location	Body (cg19639560)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.04E+00	Statistic Test	p-value:3.93E-02; Z-score:2.44E-01
Methylation in Case	5.55E-01 (Median)	Methylation in Control	5.31E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Colorectal cancer	9 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS1500 (cg16374411)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.13E+00	Statistic Test	p-value:1.42E-03; Z-score:7.24E-01
Methylation in Case	3.57E-01 (Median)	Methylation in Control	3.17E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS1500 (cg14950751)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.17E+00	Statistic Test	p-value:2.77E-03; Z-score:6.82E-01
Methylation in Case	2.58E-01 (Median)	Methylation in Control	2.20E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS200 (cg07011163)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.16E+00	Statistic Test	p-value:2.28E-04; Z-score:9.62E-01
Methylation in Case	1.93E-01 (Median)	Methylation in Control	1.67E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS200 (cg13181928)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.15E+00	Statistic Test	p-value:4.23E-04; Z-score:1.01E+00
Methylation in Case	2.23E-01 (Median)	Methylation in Control	1.94E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS200 (cg03892045)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.23E+00	Statistic Test	p-value:6.17E-03; Z-score:8.41E-01
Methylation in Case	5.59E-02 (Median)	Methylation in Control	4.55E-02 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS200 (cg18530716)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.16E+00	Statistic Test	p-value:1.20E-02; Z-score:5.93E-01
Methylation in Case	2.05E-01 (Median)	Methylation in Control	1.77E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	TSS200 (cg03712541)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.34E+00	Statistic Test	p-value:1.71E-02; Z-score:5.49E-01
Methylation in Case	3.15E-02 (Median)	Methylation in Control	2.35E-02 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC16A11 in colorectal cancer			[ 4 ]
Location	Body (cg05031424)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.10E+00	Statistic Test	p-value:5.53E-10; Z-score:-2.33E+00
Methylation in Case	8.07E-01 (Median)	Methylation in Control	8.85E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Hepatocellular carcinoma	9 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	TSS1500 (cg21090344)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.20E+00	Statistic Test	p-value:5.41E-04; Z-score:-7.66E-01
Methylation in Case	4.15E-01 (Median)	Methylation in Control	4.97E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	TSS1500 (cg14950751)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.17E+00	Statistic Test	p-value:2.51E-02; Z-score:-7.25E-01
Methylation in Case	2.89E-01 (Median)	Methylation in Control	3.38E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	TSS200 (cg13167631)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-2.18E+00	Statistic Test	p-value:2.00E-15; Z-score:-2.20E+00
Methylation in Case	2.44E-01 (Median)	Methylation in Control	5.33E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	Body (cg03816707)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.38E+00	Statistic Test	p-value:7.29E-24; Z-score:4.51E+00
Methylation in Case	5.10E-01 (Median)	Methylation in Control	2.14E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	Body (cg21227867)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.52E+00	Statistic Test	p-value:3.21E-19; Z-score:-4.47E+00
Methylation in Case	4.83E-01 (Median)	Methylation in Control	7.34E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	Body (cg18736141)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.51E+00	Statistic Test	p-value:1.91E-07; Z-score:-1.75E+00
Methylation in Case	1.74E-01 (Median)	Methylation in Control	2.61E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	Body (cg02489908)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.58E+00	Statistic Test	p-value:2.97E-07; Z-score:-1.94E+00
Methylation in Case	1.98E-01 (Median)	Methylation in Control	3.14E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	Body (cg19639560)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.38E+00	Statistic Test	p-value:3.12E-07; Z-score:-1.18E+00
Methylation in Case	3.92E-01 (Median)	Methylation in Control	5.39E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC16A11 in hepatocellular carcinoma			[ 5 ]
Location	Body (cg05031424)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.17E+00	Statistic Test	p-value:7.35E-05; Z-score:-8.11E-01
Methylation in Case	5.41E-01 (Median)	Methylation in Control	6.30E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Lung adenocarcinoma	3 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in lung adenocarcinoma			[ 6 ]
Location	TSS1500 (cg16374411)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.21E+00	Statistic Test	p-value:1.33E-03; Z-score:-1.85E+00
Methylation in Case	3.63E-01 (Median)	Methylation in Control	4.39E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in lung adenocarcinoma			[ 6 ]
Location	TSS1500 (cg14950751)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.30E+00	Statistic Test	p-value:2.95E-03; Z-score:-2.66E+00
Methylation in Case	3.45E-01 (Median)	Methylation in Control	4.48E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in lung adenocarcinoma			[ 6 ]
Location	TSS200 (cg13181928)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.33E+00	Statistic Test	p-value:9.35E-03; Z-score:-1.55E+00
Methylation in Case	2.50E-01 (Median)	Methylation in Control	3.32E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Pancretic ductal adenocarcinoma	13 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	TSS1500 (cg01532168)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:3.53E+00	Statistic Test	p-value:1.02E-12; Z-score:2.73E+00
Methylation in Case	4.49E-01 (Median)	Methylation in Control	1.27E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	TSS1500 (cg17445913)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.08E+00	Statistic Test	p-value:2.90E-09; Z-score:4.49E-01
Methylation in Case	1.82E-01 (Median)	Methylation in Control	1.69E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	TSS1500 (cg27435138)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.07E+00	Statistic Test	p-value:3.09E-03; Z-score:7.39E-01
Methylation in Case	8.01E-01 (Median)	Methylation in Control	7.45E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	TSS1500 (cg11699666)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.14E+00	Statistic Test	p-value:1.36E-02; Z-score:6.02E-01
Methylation in Case	5.87E-02 (Median)	Methylation in Control	5.14E-02 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	TSS200 (cg24751648)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.27E+00	Statistic Test	p-value:1.55E-04; Z-score:-1.01E+00
Methylation in Case	1.21E-01 (Median)	Methylation in Control	1.54E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.25E+00	Statistic Test	p-value:6.09E-04; Z-score:-9.65E-01
Methylation in Case	5.44E-01 (Median)	Methylation in Control	6.81E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	Body (cg26426186)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:4.47E-07; Z-score:-6.73E-01
Methylation in Case	7.66E-01 (Median)	Methylation in Control	7.83E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	Body (cg09945896)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.03E+00	Statistic Test	p-value:6.80E-05; Z-score:-7.78E-01
Methylation in Case	7.63E-01 (Median)	Methylation in Control	7.87E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	Body (cg18104539)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:1.69E-04; Z-score:-6.98E-01
Methylation in Case	9.00E-01 (Median)	Methylation in Control	9.08E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	Body (cg04794858)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.05E+00	Statistic Test	p-value:1.39E-03; Z-score:1.16E+00
Methylation in Case	8.55E-01 (Median)	Methylation in Control	8.16E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	Body (cg08799967)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.04E+00	Statistic Test	p-value:1.68E-02; Z-score:7.13E-01
Methylation in Case	8.03E-01 (Median)	Methylation in Control	7.71E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon12	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	Body (cg05369268)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.06E+00	Statistic Test	p-value:1.76E-02; Z-score:6.29E-01
Methylation in Case	9.25E-01 (Median)	Methylation in Control	8.71E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon13	Methylation of SLC16A11 in pancretic ductal adenocarcinoma			[ 7 ]
Location	3'UTR (cg05868813)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.29E+00	Statistic Test	p-value:3.02E-10; Z-score:-1.95E+00
Methylation in Case	5.68E-01 (Median)	Methylation in Control	7.35E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Panic disorder	3 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in panic disorder			[ 8 ]
Location	TSS1500 (cg14950751)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-9.02E-01	Statistic Test	p-value:1.30E-03; Z-score:-4.59E-01
Methylation in Case	-1.94E+00 (Median)	Methylation in Control	-1.75E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in panic disorder			[ 8 ]
Location	TSS200 (cg03892045)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-9.68E-01	Statistic Test	p-value:2.69E-02; Z-score:-2.43E-01
Methylation in Case	-4.85E+00 (Median)	Methylation in Control	-4.69E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in panic disorder			[ 8 ]
Location	Body (cg01019875)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-8.93E-01	Statistic Test	p-value:2.77E-02; Z-score:-5.76E-01
Methylation in Case	-4.96E+00 (Median)	Methylation in Control	-4.42E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Celiac disease	1 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in celiac disease			[ 9 ]
Location	TSS200 (cg13181928)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:3.02E+00	Statistic Test	p-value:4.73E-02; Z-score:1.27E+00
Methylation in Case	8.13E-02 (Median)	Methylation in Control	2.69E-02 (Median)
Studied Phenotype	Celiac disease[ ICD-11:DA95]
Experimental Material	Patient tissue samples
Renal cell carcinoma	7 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	TSS200 (cg07011163)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.22E+00	Statistic Test	p-value:7.39E-03; Z-score:5.81E-01
Methylation in Case	2.26E-01 (Median)	Methylation in Control	1.85E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	TSS200 (cg13181928)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.63E+00	Statistic Test	p-value:9.31E-03; Z-score:2.32E+00
Methylation in Case	4.18E-01 (Median)	Methylation in Control	2.56E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	TSS200 (cg03712541)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.12E+00	Statistic Test	p-value:1.20E-02; Z-score:-1.43E-01
Methylation in Case	5.28E-02 (Median)	Methylation in Control	5.90E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	TSS200 (cg08352268)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.07E+00	Statistic Test	p-value:2.32E-02; Z-score:1.43E-01
Methylation in Case	9.97E-02 (Median)	Methylation in Control	9.36E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	Body (cg02489908)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.16E+00	Statistic Test	p-value:1.25E-03; Z-score:1.46E+00
Methylation in Case	3.23E-01 (Median)	Methylation in Control	2.79E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	Body (cg18736141)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.19E+00	Statistic Test	p-value:1.28E-02; Z-score:4.71E-01
Methylation in Case	1.39E-01 (Median)	Methylation in Control	1.16E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC16A11 in clear cell renal cell carcinoma			[ 10 ]
Location	Body (cg05031424)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.05E+00	Statistic Test	p-value:2.56E-02; Z-score:-6.76E-01
Methylation in Case	7.02E-01 (Median)	Methylation in Control	7.34E-01 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Papillary thyroid cancer	3 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC16A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg05031424)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.03E+00	Statistic Test	p-value:1.43E-05; Z-score:-9.34E-01
Methylation in Case	8.41E-01 (Median)	Methylation in Control	8.62E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC16A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg02489908)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.16E+00	Statistic Test	p-value:4.41E-05; Z-score:1.21E+00
Methylation in Case	3.28E-01 (Median)	Methylation in Control	2.82E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC16A11 in papillary thyroid cancer			[ 11 ]
Location	Body (cg03096732)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.23E+00	Statistic Test	p-value:3.82E-03; Z-score:-8.50E-01
Methylation in Case	1.64E-01 (Median)	Methylation in Control	2.03E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Lymphoma	1 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Significant hypermethylation of SLC16A11 in lymphoma than that in healthy individual
Studied Phenotype	Lymphoma [ICD-11:2B30]
The Methylation Level of Disease Section Compare with the Healthy Individual	p-value:5.33E-09; Fold-change:0.407605361; Z-score:5.731705893
DT methylation level in the diseased tissue of patients DT methylation level in the normal tissue of healthy individuals
			Please Click the above Thumbnail to View/Download the Methylation Barchart for All Samples
Download DT methylation data of patients in the disease section of the tissue Download DT methylation data in the tissue of healthy individual

References
1	Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.
2	DNA Methylation Dynamics in Urological Tumors.
3	Genome-wide Scan for Methylation Profiles in Breast Cancer
4	Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
5	Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
6	DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
7	Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
8	DNA Methylation signatures in panic disorder. Transl Psychiatry. 2017 Dec 18;7(12):1287.
9	The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region. Mol Ther Oncolytics. 2019 Feb 5;12:235-245.
10	A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
11	Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.

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