Detail Information of Disease-specific Protein Abundances
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0497 Transporter Info | ||||
| Gene Name | SLC9C1 | ||||
| Protien Name | Sodium/hydrogen exchanger 10 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Disease-specific Protein Abundances of DT (DPAD) | |||||
|---|---|---|---|---|---|
| ICD-11: 02 Neoplasm | |||||
| [+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Colon | ||||
| The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5662599586812185; Fold-change:0.75; Z-score:0.6152040436788621 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7114589271359335; Fold-change:0.9908617414478186; Z-score:-0.089018614 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6926040502923161; Fold-change:0.7368421052631579; Z-score:-0.167073938 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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the Expression Barchart for All Samples
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| [+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0004109867653928; Fold-change:0.0285929270127915; Z-score:-1.969936039 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
| [+] ICD-11: 5A11 Type 2 diabetes mellitus | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Islet of langerhans | ||||
| The Specified Disease | Type ii diabetes mellitus [ICD-11:5A11] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2500302237879543; Fold-change:0.5526315789473685; Z-score:-2.288138309 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle | ||||
| The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0399968259576519; Fold-change:1.0383808414269042; Z-score:1.4409861455719726 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
| [+] ICD-11: 6A02 Autism spectrum disorder | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brain | ||||
| The Specified Disease | Autism [ICD-11:6A02] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Dorsolateral prefrontal cortex | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3576472987610316; Fold-change:inf; Z-score:0.3038295313458103 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 08 Disease of the nervous system | |||||
| [+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Frontal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4056719851364251; Fold-change:0.9887375714904526; Z-score:-0.262050619 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Hippocampus | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4721666939297899; Fold-change:1.0034861725623685; Z-score:0.4029232076766119 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Temporal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.703027361771617; Fold-change:1.0142828435142113; Z-score:-0.146702758 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Muscle | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0331875935396097; Fold-change:2.142857142857143; Z-score:1.1271847127337178 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myoblast | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4227085308450795; Fold-change:0.3157894736842105; Z-score:-0.543928293 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myotube | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5823154478951236; Fold-change:2; Z-score:0.7505553499465134 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C71.0 Myotonic dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart left ventricle | ||||
| The Specified Disease | Myotonic dystrophy [ICD-11:8C71.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3436919047841926; Fold-change:0.3296703296703296; Z-score:-0.925460312 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 11 Disease of the circulatory system | |||||
| [+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Left ventricle | ||||
| The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0941198772978698; Fold-change:1.113465075531919; Z-score:2.253875347099732 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 13 Disease of the digestive system | |||||
| [+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Ileum | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0694350095637373; Fold-change:0.7142857142857143; Z-score:-0.281865933 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colonic mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.100356449694148; Fold-change:0.962028476324306; Z-score:-0.927452166 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Caecum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9724405263624782; Fold-change:1.0254521270024213; Z-score:-0.044187311 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Left colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1981192966047946; Fold-change:0.9290791107918565; Z-score:-1.311153593 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Rectum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0132690823068729; Fold-change:0.9334984131616278; Z-score:-2.165229996 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Transverse colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4660042983978982; Fold-change:0.9624094008013688; Z-score:-0.901343704 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 14 Disease of the skin | |||||
| [+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Mouth mucosa | ||||
| The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0891512435587124; Fold-change:1.109538190600727; Z-score:1.504585827173612 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:1.4363033442429775e-06; Fold-change:0.0255831452219714; Z-score:-1.965649054 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 15 Disease of the musculoskeletal system/connective tissue | |||||
| [+] ICD-11: FA0Z Osteoarthritis, unspecified site | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Bone | ||||
| The Specified Disease | Osteoarthritis [ICD-11:FA0Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6286599999107683; Fold-change:0.99353020486493; Z-score:-0.15595229 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 20 Developmental anomaly | |||||
| [+] ICD-11: LA88.2 Tetralogy of Fallot | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart ventricle | ||||
| The Specified Disease | Tetralogy of fallot [ICD-11:LA88.2] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0353818817157439; Fold-change:2; Z-score:2.714472124338996 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.00 Unicoronal craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Coronal craniosynostosis [ICD-11:LB70.00] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9010603081912444; Fold-change:2.5; Z-score:0.0833333333333333 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.02 Lambdoid craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Lambdoid craniosynostosis [ICD-11:LB70.3] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.03 Metopic craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Metopic craniosynostosis [ICD-11:LB70.2] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7796004479065098; Fold-change:1; Z-score:-0.214285714 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.0Y Sagittal craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Sagittal craniosynostosis [ICD-11:LB70.1] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0004109867653928; Fold-change:0.0285929270127915; Z-score:-1.969936039 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 25 Codes for special purposes | |||||
| [+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1141972010766058; Fold-change:0.5795795795795796; Z-score:-0.702470009 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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|
 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| The Studied Tissue | Colon | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.002630404357919; Fold-change:0.3507972665148063; Z-score:-1.885096775 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
|||||
|
 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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