Detail Information of Disease-specific Protein Abundances
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0488 Transporter Info | ||||
| Gene Name | SLC9A4 | ||||
| Protien Name | Sodium/hydrogen exchanger 4 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Disease-specific Protein Abundances of DT (DPAD) | |||||
|---|---|---|---|---|---|
| ICD-11: 02 Neoplasm | |||||
| [+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Colon | ||||
| The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0004432175496602; Fold-change:18.75; Z-score:3.746581579092908 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0049658905230382; Fold-change:1.0371784379270048; Z-score:1.9705980122576976 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1923001116747202; Fold-change:1.2945736434108528; Z-score:3.6512678653744 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0003042948048259; Fold-change:0.1071428571428571; Z-score:-2.084300399 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
| [+] ICD-11: 5A11 Type 2 diabetes mellitus | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Islet of langerhans | ||||
| The Specified Disease | Type ii diabetes mellitus [ICD-11:5A11] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8456711339658727; Fold-change:1; Z-score:0.1443375672974065 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle | ||||
| The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0061422244549089; Fold-change:1.16389109406741; Z-score:3.083982957002265 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
| [+] ICD-11: 6A20 Schizophrenia | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24-1.png)
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_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24-1.png)
|
_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Dorsolateral prefrontal cortex | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 08 Disease of the nervous system | |||||
| [+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Frontal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.254673338530853; Fold-change:1.0055281322122909; Z-score:0.451090221691867 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Hippocampus | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3379360590080399; Fold-change:1.0144536491858376; Z-score:0.4618311196355918 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Temporal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7399062078299014; Fold-change:1.0105752637075032; Z-score:0.1320153556830459 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Muscle | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6766076161972472; Fold-change:1.0105820105820107; Z-score:0.1518203122155801 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myoblast | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3095138671346485; Fold-change:0.3023255813953488; Z-score:-0.604020599 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myotube | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3069170120431017; Fold-change:1.2569832402234635; Z-score:1.0429008231370729 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 11 Disease of the circulatory system | |||||
| [+] ICD-11: BA8Z Diseases of coronary artery, unspecified (coronary artery disease) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Epicardial fat | ||||
| The Specified Disease | Coronary artery disease [ICD-11:BA8Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1127497048860094; Fold-change:0.9748045923216124; Z-score:-0.589242173 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Subcutaneous adipose tissue | ||||
| The Specified Disease | Coronary artery disease [ICD-11:BA8Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0366647157711013; Fold-change:0.9787071747611892; Z-score:-1.197912603 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Left ventricle | ||||
| The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9190348339245878; Fold-change:1.00749073970896; Z-score:0.0602338755048528 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 13 Disease of the digestive system | |||||
| [+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Ileum | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.957305013359758; Fold-change:1; Z-score:-0.007804487 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colonic mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0057123689055679; Fold-change:0.9490545992473682; Z-score:-1.419179037 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| The Studied Tissue | Ileal mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6408557288503254; Fold-change:1.0026683161385923; Z-score:0.3759532156302293 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Caecum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2708436036016477; Fold-change:1.1110270571322611; Z-score:3.305113912624952 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| The Studied Tissue | Left colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.012008419094145; Fold-change:0.864377176002214; Z-score:-20.57430965 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| The Studied Tissue | Rectum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3060593105115064; Fold-change:1.017016770500048; Z-score:1.0922910319399457 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| The Studied Tissue | Transverse colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4896686785762794; Fold-change:1.0130832326309915; Z-score:0.6192723602870495 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| ICD-11: 14 Disease of the skin | |||||
| [+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Mouth mucosa | ||||
| The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5316398102970961; Fold-change:0.8989010059965378; Z-score:-0.433563389 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:8.738583755753106e-06; Fold-change:0.1071428571428571; Z-score:-1.985179112 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| ICD-11: 15 Disease of the musculoskeletal system/connective tissue | |||||
| [+] ICD-11: FA0Z Osteoarthritis, unspecified site | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Bone | ||||
| The Specified Disease | Osteoarthritis [ICD-11:FA0Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1064779864420475; Fold-change:1.0262284330526004; Z-score:0.9093955454530572 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 20 Developmental anomaly | |||||
| [+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0003042948048259; Fold-change:0.1071428571428571; Z-score:-2.084300399 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 25 Codes for special purposes | |||||
| [+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Colon | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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