Detail Information of Disease-specific Protein Abundances
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0320 Transporter Info | ||||
| Gene Name | SLC36A3 | ||||
| Protien Name | Proton-coupled amino acid transporter 3 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Disease-specific Protein Abundances of DT (DPAD) | |||||
|---|---|---|---|---|---|
| ICD-11: 02 Neoplasm | |||||
| [+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Colon | ||||
| The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0081930183352756; Fold-change:4; Z-score:5.522869121510425 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0388931304479208; Fold-change:1.0316526599305302; Z-score:0.4921652699333237 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2127153043816404; Fold-change:1.6875; Z-score:1.121209506627418 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0008474103612603; Fold-change:0.1126760563380281; Z-score:-1.790956124 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
| [+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle | ||||
| The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0205340432559046; Fold-change:1.1413687480318142; Z-score:2.0518645268504776 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
| [+] ICD-11: 6A20 Schizophrenia | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0493321956399217; Fold-change:inf; Z-score:inf | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Dorsolateral prefrontal cortex | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2792453373713642; Fold-change:inf; Z-score:0.3585245574043688 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 08 Disease of the nervous system | |||||
| [+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Frontal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5641754166550934; Fold-change:1.0158957672382496; Z-score:0.2223061451495067 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Hippocampus | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3053671864210044; Fold-change:1.0155494821378732; Z-score:0.5288391834799313 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Temporal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1913200148969514; Fold-change:0.9811767245064424; Z-score:-0.561513334 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Muscle | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5929175940411798; Fold-change:1.2857142857142858; Z-score:0.2190511019246725 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myoblast | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9237672134183462; Fold-change:1.12; Z-score:0.0543928293220421 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myotube | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3327133817725204; Fold-change:1.4444444444444444; Z-score:1.4740614447359863 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C71.0 Myotonic dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart left ventricle | ||||
| The Specified Disease | Myotonic dystrophy [ICD-11:8C71.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2790825394934028; Fold-change:1.5; Z-score:1.732050807568877 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 11 Disease of the circulatory system | |||||
| [+] ICD-11: BD10 Congestive heart failure | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle tissue | ||||
| The Specified Disease | Heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6845283355605284; Fold-change:inf; Z-score:0.2886751345948128 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Left ventricle | ||||
| The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5458141329494128; Fold-change:1.0011260294465518; Z-score:-0.24772045 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 13 Disease of the digestive system | |||||
| [+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Ileum | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8722434332968554; Fold-change:0.6666666666666666; Z-score:-0.029414168 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colonic mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0429476624642093; Fold-change:0.9515471869079722; Z-score:-0.977393772 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Caecum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7595213735092051; Fold-change:0.968196462521794; Z-score:-0.403116037 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Left colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3026931413527763; Fold-change:0.9074485490435013; Z-score:-0.840624292 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Rectum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.259081597670996; Fold-change:0.959317855118779; Z-score:-1.087579638 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Transverse colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5054525207012472; Fold-change:1.0114744844331216; Z-score:0.5374727505593131 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| ICD-11: 14 Disease of the skin | |||||
| [+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Mouth mucosa | ||||
| The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.795580522038273; Fold-change:0.9772167081780418; Z-score:-0.156028443 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:7.53190672742444e-06; Fold-change:0.056338028169014; Z-score:-1.821781065 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 15 Disease of the musculoskeletal system/connective tissue | |||||
| [+] ICD-11: FA0Z Osteoarthritis, unspecified site | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Bone | ||||
| The Specified Disease | Osteoarthritis [ICD-11:FA0Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4101530757809084; Fold-change:1.0154783589147; Z-score:0.3122300572545048 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 20 Developmental anomaly | |||||
| [+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0008474103612603; Fold-change:0.1126760563380281; Z-score:-1.790956124 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 25 Codes for special purposes | |||||
| [+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colon | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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|
 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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