Detail Information of Disease-specific Protein Abundances
General Information of Drug Transporter (DT) | |||||
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DT ID | DTD0319 Transporter Info | ||||
Gene Name | SLC36A2 | ||||
Protien Name | Proton-coupled amino acid transporter 2 | ||||
Gene ID | |||||
UniProt ID |
Disease-specific Protein Abundances of DT (DPAD) | |||||
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ICD-11: 02 Neoplasm | |||||
[+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Colon | ||||
The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0002095999773304; Fold-change:inf; Z-score:3.890726916368704 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
The Studied Tissue | Lung | ||||
The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0023893289030802; Fold-change:1.024005861285992; Z-score:0.8540682270067179 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
The Studied Tissue | Lung | ||||
The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7111190241043182; Fold-change:0.6818181818181818; Z-score:0.3487932901193186 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skin | ||||
The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0063635899546364; Fold-change:0.1538461538461538; Z-score:-1.295812701 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
[+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skeletal muscle | ||||
The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9040291087309962; Fold-change:0.9867189197012152; Z-score:0.0657131824300547 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
[+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Dorsolateral prefrontal cortex | ||||
The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1450271992722837; Fold-change:1; Z-score:0.6651859526767916 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 08 Disease of the nervous system | |||||
[+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
The Studied Tissue | Frontal cortex | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7387753198584388; Fold-change:0.9918030599226632; Z-score:0.1187998247576018 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Hippocampus | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.020639070823168; Fold-change:1.0367806448289556; Z-score:1.8797315066953224 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Temporal cortex | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3358613463677347; Fold-change:1.0085922534855347; Z-score:0.3417436168160195 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
The Studied Tissue | Muscle | ||||
The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1342692592168762; Fold-change:1.0480819758276405; Z-score:0.7742238763698404 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Myoblast | ||||
The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1324189222202493; Fold-change:0.3333333333333333; Z-score:-1.414213562 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Myotube | ||||
The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2026060729924425; Fold-change:2.6666666666666665; Z-score:1.3333333333333333 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 8C71.0 Myotonic dystrophy | Click to Show/Hide the Full List | ||||
The Studied Tissue | Heart left ventricle | ||||
The Specified Disease | Myotonic dystrophy [ICD-11:8C71.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9498231505818404; Fold-change:0.7142857142857143; Z-score:-0.040056118 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 11 Disease of the circulatory system | |||||
[+] ICD-11: BD10 Congestive heart failure | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skeletal muscle tissue | ||||
The Specified Disease | Heart failure [ICD-11:BD10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8084866936460513; Fold-change:0.8208640674394099; Z-score:0.3826091087892282 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Left ventricle | ||||
The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1501002238156123; Fold-change:1.0521112284750556; Z-score:0.8845186241295763 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 13 Disease of the digestive system | |||||
[+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
The Studied Tissue | Ileum | ||||
The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.946504738114545; Fold-change:1; Z-score:0.0131102875759155 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Colonic mucosa | ||||
The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1093562091025609; Fold-change:0.9617251299584229; Z-score:-0.969806173 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Caecum | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.180310509308343; Fold-change:0.945690624031215; Z-score:-1.541543337 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Left colon | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0133648270101668; Fold-change:0.892680056086885; Z-score:-3.725381559 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Rectum | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4714884345930193; Fold-change:0.9469324829031186; Z-score:-0.570735983 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Transverse colon | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2515798801144672; Fold-change:0.9560097066342226; Z-score:-0.698232219 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 14 Disease of the skin | |||||
[+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Mouth mucosa | ||||
The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9257071788589069; Fold-change:0.849989093700533; Z-score:-0.057435875 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skin | ||||
The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 15 Disease of the musculoskeletal system/connective tissue | |||||
[+] ICD-11: FA0Z Osteoarthritis, unspecified site | Click to Show/Hide the Full List | ||||
The Studied Tissue | Bone | ||||
The Specified Disease | Osteoarthritis [ICD-11:FA0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0007438047772301; Fold-change:1.1887803450733672; Z-score:1.1311042800829698 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 20 Developmental anomaly | |||||
[+] ICD-11: LA88.2 Tetralogy of Fallot | Click to Show/Hide the Full List | ||||
The Studied Tissue | Heart ventricle | ||||
The Specified Disease | Tetralogy of fallot [ICD-11:LA88.2] | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skin | ||||
The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0063635899546364; Fold-change:0.1538461538461538; Z-score:-1.295812701 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 25 Codes for special purposes | |||||
[+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
The Studied Tissue | Lung | ||||
The Specified Disease | Covid [ICD-11:RA01.0] | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Colon | ||||
The Specified Disease | Covid [ICD-11:RA01.0] | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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