Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01201
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| Drug Name |
Phenylephrine
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| Synonyms |
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol; (R)-2-Hydroxy-2-(3-hydroxyphenyl)-N-methylethylamine; (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol; Ah-Chew; Ak-dilate; Ak-nefrin; Alcon Efrin; Alconefrin Nasal Drops 12; Alconefrin Nasal Drops 25; Alconefrin Nasal Drops 50; Alconefrin Nasal Spray 25; Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)-(9CI); Cyclomydril; Dilatair; Dionephrine; Doktors; Duration; Fenilefrina; Fenilefrina [INN-Spanish]; I-Phrine; Isophrim; Isophrin; Isopto Frin; L-(3-Hydroxyphenyl)-N-methylethanolamine; L-1-(m-Hydroxyphenyl)-2-methylaminoethanol; L-Phenylephedrine; L-Phenylephrine; L-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene; L-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol; M-Methylaminoethanolphenol; M-Oxedrine; M-Sympathol; M-Sympatol; M-Synephrine; Mesaton; Mesatone; Mesatonum; Metaoxedrin; Metaoxedrine; Metaoxedrinum; Metasympatol; Metasynephrine; Metsatonum; Mezaton; Minims Phenylephrine; Mydfrin; Mydfrin (TN); Neo-Synephrine; Neo-Synephrine Nasal Drops; Neo-Synephrine Nasal Jelly; Neo-Synephrine Nasal Spray; Neofrin; Neosynephrine; Nostril; Nostril Spray Pump; Nostril Spray Pump Mild; Ocu-Phrin Sterile Eye Drops; Ocugestrin; Phenoptic; Phenylephrine (INN); Phenylephrine Minims; Phenylephrine Minims (TN); Phenylephrine [INN:BAN]; Phenylephrinum; Phenylephrinum [INN-Latin]; Prefrin Liquifilm; R(-)-Phenylephrine; Relief Eye Drops for Red Eyes; Spersaphrine; Tannins, compds. with (R)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol; Visadron
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Ophthalmologicals
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C9H13NO2
|
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| Canonical SMILES |
CNCC(C1=CC(=CC=C1)O)O
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| InChI |
InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1
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| InChIKey |
SONNWYBIRXJNDC-VIFPVBQESA-N
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| CAS Number |
CAS 59-42-7
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| Pharmaceutical Properties | Molecular Weight | 167.2 | Topological Polar Surface Area | 52.5 | ||
| Heavy Atom Count | 12 | Rotatable Bond Count | 3 | |||
| Hydrogen Bond Donor Count | 3 | Hydrogen Bond Acceptor Count | 3 | |||
| XLogP |
-0.3
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| PubChem CID | ||||||
| PubChem SID |
103367925
,104310950
,11111644
,11335772
,11361011
,11363995
,11366557
,11369119
,11371740
,11374452
,11377281
,11461983
,11485016
,11489096
,11490586
,11492782
,11494915
,11533358
,117480201
,124750098
,126524414
,126687263
,15147117
,15219459
,29225054
,3138730
,46506961
,47216760
,47440232
,47588980
,47885392
,48184976
,48334474
,48416424
,49892965
,50100321
,50104255
,50104256
,53787092
,56311763
,56311811
,598369
,77849473
,7980308
,8153766
,87574602
,90340906
,93166315
,96025051
,9645
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| ChEBI ID |
ChEBI:8093
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | ABCG1 | Transporter Info | ATP-binding cassette sub-family G member 1 | Substrate | [1] | |
| References | ||||||
| 1 | SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis. Circ Res. 2025 Feb 28;136(5):491-507. | |||||
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