Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00065
|
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| Drug Name |
L-ornithine
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| Synonyms |
OKG; Ornithine
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| Drug Type |
Small molecular drug
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| Indication | Immunomodulatory and wound-healing [ICD11:EL8Y] | Preclinical | [1] | |||
| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C5H12N2O2
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| Canonical SMILES |
C(CC(C(=O)O)N)CN
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| InChI |
InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
|
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| InChIKey |
AHLPHDHHMVZTML-BYPYZUCNSA-N
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| CAS Number |
CAS 70-26-8
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| Pharmaceutical Properties | Molecular Weight | 132.16 | Topological Polar Surface Area | 89.3 | ||
| Heavy Atom Count | 9 | Rotatable Bond Count | 4 | |||
| Hydrogen Bond Donor Count | 3 | Hydrogen Bond Acceptor Count | 4 | |||
| XLogP |
-4.4
|
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| PubChem CID | ||||||
| PubChem SID |
103241659
,104311559
,117531295
,118048307
,118111072
,119502991
,124361098
,124384980
,125264688
,126523083
,126630015
,126656480
,127407391
,132521939
,134971826
,134988625
,135078813
,135651508
,137009105
,137101066
,142084810
,144075755
,144079899
,15119954
,26707944
,29225258
,3134135
,3377
,46392150
,46392411
,46394355
,46505239
,47960034
,49999390
,50069752
,56260878
,57323300
,584746
,76245758
,81055054
,8143361
,8153942
,835599
,841777
,85164988
,87325835
,87692687
,92298615
,92712846
,96024989
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| ChEBI ID |
ChEBI:15729
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | CAT2 | Transporter Info | Cationic amino acid transporter 2 | Substrate | [2] | |
| References | ||||||
| 1 | National Center for Advancing Translational Science-Inxight: drug (E524N2IXA3) | |||||
| 2 | Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Eur J Hum Genet. 2019 Apr;27(4):621-630. | |||||
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