Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00043
|
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| Drug Name |
Fructose
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| Synonyms |
(3S,4R,5R)-1,3,4,5,6-pentahydroxyhexan-2-one; 30237-26-4; 53188-23-1; 57-48-7; AI3-23514; Apir Levulosa; CCRIS 3335; D(-)-Fructose; D(-)-Fructose, 99%; D-(-)-Fructose; D-(-)-Fructose, > D-(-)-Levulose; D-Levulose; D-fructose; DL-Fructose; EINECS 200-333-3; Fructon; Fructose solution; Fructose, D-; Fructose, pure; Furucton; Hi-Fructo 970; Krystar 300; Levulosa; Levulosa Baxter; Levulosa Braun; Levulosa Ibys; Levulosa Ife; Levulosa Mein; Levulosado Braun; MFCD00148910; Methose; Nevulose; Sugar, fruit; arabino-Hexulose; keto-D-fructose
|
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| Drug Type |
Small molecular drug
|
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| Indication | Emesis [ICD11:MD90] | Approved | [1] | |||
| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C6H12O6
|
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| Canonical SMILES |
C(C(C(C(C(=O)CO)O)O)O)O
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| InChI |
InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1
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| InChIKey |
BJHIKXHVCXFQLS-UYFOZJQFSA-N
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| CAS Number |
CAS 57-48-7
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| Pharmaceutical Properties | Molecular Weight | 180.16 | Topological Polar Surface Area | 118 | ||
| Heavy Atom Count | 12 | Rotatable Bond Count | 5 | |||
| Hydrogen Bond Donor Count | 5 | Hydrogen Bond Acceptor Count | 6 | |||
| XLogP |
-3.2
|
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| PubChem CID | ||||||
| PubChem SID |
103822107
,104225898
,104310785
,117559373
,117613538
,123120957
,124759816
,127301939
,127301940
,127301941
,127301942
,127301943
,127301944
,127301945
,127301946
,127301947
,127301948
,127301949
,127301950
,127301951
,127301952
,127301953
,127301954
,127301955
,127301956
,127301957
,127301958
,127301959
,127301960
,127301961
,127301962
,127301963
,127301964
,127301965
,127301966
,13089
,14716675
,15339912
,16877774
,29204153
,29225000
,46491008
,46530493
,49970811
,57323096
,68530625
,75359324
,7847182
,8153720
,92298678
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| ChEBI ID |
ChEBI:48095
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | GLUT5 | Transporter Info | Glucose transporter type 5 | Substrate | [2] | |
| GLUT7 | Transporter Info | Glucose transporter type 7 | Substrate | [3] | ||
| SGLT4 | Transporter Info | Sodium/glucose cotransporter 4 | Substrate | [4] | ||
| References | ||||||
| 1 | Fructose was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
| 2 | Dexamethasone sensitizes the neonatal intestine to fructose induction of intestinal fructose transporter (Slc2A5) function. Endocrinology. 2008 Jan;149(1):409-23. | |||||
| 3 | Functional Properties and Genomics of Glucose Transporters. Curr Genomics. 2007 Apr; 8(2): 113128. | |||||
| 4 | SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose. Life Sci. 2005 Jan 14;76(9):1039-50. | |||||
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