Detail Information of Exogenous Modulation
General Information of Drug Transporter (DT) | |||||
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DT ID | DTD0110 Transporter Info | ||||
Gene Name | SLC16A6 | ||||
Transporter Name | Monocarboxylate transporter 7 | ||||
Gene ID | |||||
UniProt ID | |||||
Exogenous factors (drugs, dietary constituents, etc.) Modulation of This DT (EGM) | |||||
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Approved Drug |
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Sulindac |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Sulindac increases the expression of SLC16A6 | [1] | |||
Fluorouracil |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Fluorouracil inhibits the expression of SLC16A6 | [2] | |||
Zinc Acetate |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Zinc Acetate increases the expression of SLC16A6 | [3] | |||
Copper Sulfate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Copper Sulfate increases the expression of SLC16A6 | [4] | |||
Dasatinib |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dasatinib inhibits the expression of SLC16A6 | [5] | |||
Progesterone |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Progesterone inhibits the expression of SLC16A6 | [6] | |||
Liothyronine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Liothyronine increases the expression of SLC16A6 | [7] | |||
Acetaminophen |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acetaminophen increases the expression of SLC16A6 | [8] | |||
Azathioprine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Azathioprine increases the expression of SLC16A6 | [9] | |||
Zidovudine |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Zidovudine inhibits the expression of SLC16A6 | [10] | |||
Ibuprofen |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Ibuprofen increases the expression of SLC16A6 | [11] | |||
Urethane |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Urethane inhibits the expression of SLC16A6 | [12] | |||
Leflunomide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Leflunomide increases the expression of SLC16A6 | [13] | |||
Doxorubicin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Doxorubicin inhibits the expression of SLC16A6 | [14] | |||
Hydroquinone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Hydroquinone inhibits the expression of SLC16A6 | [16] | |||
Tretinoin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tretinoin increases the expression of SLC16A6 | [17] | |||
Estradiol |
5 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Estradiol inhibits the expression of SLC16A6 | [18] | |||
Cyclosporine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cyclosporine increases the expression of SLC16A6 | [19] | |||
Valproic Acid |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Valproic Acid increases the expression of SLC16A6 | [20] | |||
Drug Marketed but not Approved by US FDA |
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Rotenone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Rotenone increases the expression of SLC16A6 | [15] | |||
Drug in Phase 2 Trial |
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Motexafin gadolinium |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Motexafin gadolinium increases the expression of SLC16A6 | [3] | |||
Bisphenol A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Bisphenol A increases the expression of SLC16A6 | [29] | |||
Drug in Phase 1 Trial |
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Quercetin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Quercetin increases the expression of SLC16A6 | [18] | |||
Trichostatin A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Trichostatin A increases the expression of SLC16A6 | [25] | |||
Dihydrotestosterone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dihydrotestosterone increases the expression of SLC16A6 | [30] | |||
Drug in Preclinical Test |
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(+)-JQ1 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
(+)-JQ1 inhibits the expression of SLC16A6 | [35] | |||
Investigative Drug |
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Beta-naphthoflavone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Beta-naphthoflavone increases the expression of SLC16A6 | [21] | |||
Natural Product |
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Particulate Matter |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Particulate Matter increases the expression of SLC16A6 | [31] | |||
Tobacco Smoke Pollution |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tobacco Smoke Pollution increases the expression of SLC16A6 | [34] | |||
Caffeine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Caffeine results in increased phosphorylation of SLC16A6 protein | [46] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Traditional Medicine |
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Jinfukang |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Jinfukang increases the expression of SLC16A6 | [28] | |||
Environmental toxicant |
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Polychlorinated dibenzodioxin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Polychlorinated dibenzodioxin increases the expression of SLC16A6 | [18] | |||
Mycotoxins |
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Aflatoxin B1 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Aflatoxin B1 increases the expression of SLC16A6 | [32] | |||
Acute Toxic Substance |
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Oxyquinoline |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Oxyquinoline inhibits the expression of SLC16A6 | [18] | |||
Formaldehyde |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Formaldehyde inhibits the expression of SLC16A6 | [22] | |||
Thimerosal |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Thimerosal increases the expression of SLC16A6 | [27] | |||
Acrylamide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrylamide increases the expression of SLC16A6 | [33] | |||
Carcinogen |
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Ethyl Methanesulfonate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Ethyl Methanesulfonate inhibits the expression of SLC16A6 | [22] | |||
Benzo(a)pyrene |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Benzo(a)pyrene increases the expression of SLC16A6 | [32] | |||
Nickel |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Nickel results in increased expression of SLC16A6 mRNA | [57] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Health and Environmental Toxicant |
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1-methyl-4-phenylpyridinium |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
1-methyl-4-phenylpyridinium increases the expression of SLC16A6 | [24] | |||
Butyraldehyde |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Butyraldehyde increases the expression of SLC16A6 | [26] | |||
Herbicide |
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Diuron |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Diuron increases the expression of SLC16A6 | [23] | |||
Chemical Compound |
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DT Modulation1 |
Fluorouracil results in increased expression of SLC16A6 mRNA | [53] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
SLC16A6 protein affects the susceptibility to Fluorouracil | [2] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Zinc Acetate co-treated with motexafin gadolinium results in increased expression of SLC16A6 mRNA | [3] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Estradiol co-treated with Progesterone results in decreased expression of SLC16A6 mRNA | [48] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Progesterone co-treated with Estradiol results in decreased expression of SLC16A6 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Zidovudine results in increased expression of SLC16A6 mRNA | [10] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Estradiol co-treated with Progesterone results in decreased expression of SLC16A6 mRNA | [48] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Estradiol co-treated with TGFB1 protein results in decreased expression of SLC16A6 mRNA | [49] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Estradiol results in increased expression of SLC16A6 mRNA | [50] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation4 |
Progesterone co-treated with Estradiol results in decreased expression of SLC16A6 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC16A6 mRNA | [27] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Valproic Acid affects the expression of SLC16A6 mRNA | [64] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Pentanal |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Pentanal increases the expression of SLC16A6 | [26] | |||
DT Modulation1 |
AHR protein affects the reaction Benzo(a)pyrene results in increased expression of SLC16A6 mRNA | [42] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Benzo(a)pyrene affects the expression of SLC16A6 mRNA | [43] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
1-Methyl-4-phenylpyridinium |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
1-Methyl-4-phenylpyridinium results in increased expression of SLC16A6 mRNA | [24] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
2,4,5,2',4',5'-hexachlorobiphenyl |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of SLC16A6 mRNA | [36] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
3,4-dichloroaniline |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
3,4-dichloroaniline results in increased expression of SLC16A6 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC16A6 mRNA | [27] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC16A6 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
8-Bromo Cyclic Adenosine Monophosphate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC16A6 mRNA | [38] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Acrolein |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Aldehydes |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Aldehydes results in increased expression of SLC16A6 mRNA | [40] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
alpha-pinene |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Amphotericin B |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Amphotericin B analog results in increased expression of SLC16A6 mRNA | [41] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
benzo(e)pyrene |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
benzo(e)pyrene results in increased methylation of SLC16A6 intron | [44] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
beta-Naphthoflavone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
beta-Naphthoflavone results in increased expression of SLC16A6 mRNA | [21] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
bisphenol A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
bisphenol A results in increased expression of SLC16A6 mRNA | [29] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
butyraldehyde |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
butyraldehyde results in increased expression of SLC16A6 mRNA | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Cadmium Chloride |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cadmium Chloride results in decreased expression of SLC16A6 mRNA | [45] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
CGP 52608 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
CGP 52608 promotes the reaction RORA protein binds to SLC16A6 gene | [47] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
dorsomorphin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC16A6 mRNA | [27] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Etoposide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
SLC16A6 protein affects the susceptibility to Etoposide | [52] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
FR900359 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
FR900359 results in decreased phosphorylation of SLC16A6 protein | [54] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
hydroquinone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
hydroquinone results in decreased expression of SLC16A6 mRNA | [16] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
licochalcone B |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
licochalcone B results in decreased expression of SLC16A6 mRNA | [55] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
methacrylaldehyde |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Methapyrilene |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Methapyrilene results in increased methylation of SLC16A6 intron | [44] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Methylcholanthrene |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Methylcholanthrene promotes the reaction AHR protein binds to SLC16A6 promoter | [56] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
methylmercuric chloride |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
methylmercuric chloride results in increased expression of SLC16A6 mRNA | [20] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Methyl Methanesulfonate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Methyl Methanesulfonate results in decreased expression of SLC16A6 mRNA | [22] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Mitomycin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
SLC16A6 protein affects the susceptibility to Mitomycin | [52] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Mitoxantrone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
SLC16A6 protein affects the susceptibility to Mitoxantrone | [52] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
motexafin gadolinium |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
motexafin gadolinium results in increased expression of SLC16A6 mRNA | [3] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Zinc Acetate co-treated with motexafin gadolinium results in increased expression of SLC16A6 mRNA | [3] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
N-Nitrosopyrrolidine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
N-Nitrosopyrrolidine results in increased expression of SLC16A6 mRNA | [32] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Okadaic Acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Okadaic Acid results in increased expression of SLC16A6 mRNA | [58] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Oxygen |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Oxygen deficiency results in increased expression of SLC16A6 mRNA | [11] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Ozone |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Volatile Organic Compounds co-treated with Ozone results in decreased expression of SLC16A6 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
pentanal |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
pentanal results in increased expression of SLC16A6 mRNA | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
perfluorooctanoic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
perfluorooctanoic acid results in increased expression of SLC16A6 protein | [59] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
propionaldehyde |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
propionaldehyde results in increased expression of SLC16A6 mRNA | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Silicon Dioxide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Silicon Dioxide analog results in increased expression of SLC16A6 mRNA | [60] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
S-Nitrosoglutathione |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
S-Nitrosoglutathione results in increased expression of SLC16A6 mRNA | [61] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Tetrachlorodibenzodioxin |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tetrachlorodibenzodioxin affects the expression of SLC16A6 mRNA | [62] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Tetrachlorodibenzodioxin results in increased expression of SLC16A6 mRNA | [42] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
trichostatin A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
trichostatin A results in increased expression of SLC16A6 mRNA | [25] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Triiodothyronine |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction Triiodothyronine results in increased expression of SLC16A6 mRNA | [7] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Triiodothyronine results in increased expression of SLC16A6 mRNA | [7] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
tris(2-butoxyethyl) phosphate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
tris(2-butoxyethyl) phosphate affects the expression of SLC16A6 mRNA | [63] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
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