General Information of Drug Transporter (DT)
DT ID	DTD0530 Transporter Info
Gene Name	CACNA1H
Transporter Name	Voltage-gated calcium channel alpha Cav3.2
Gene ID	8912
UniProt ID	O95180
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	6KZO_A		Identity	57.462%
Performance	Minimized Score	-2264.854 kcal/mol
	Ramachandra Favored	Poor
	QMEANBrane Quality	Medium
Ramachandran Plot
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	Ramz Z Score	-1.69 ±0.16
	Residues in Favored Region	2055	Ramachandran favored	94.74%
	Number of Outliers	24	Ramachandran outliers	1.11%
Local Quality
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	QMEANBrane Score		0.71
AlphaFold Protein Structure Database	O95180 Click to jump to the details page
SWISS-MODEL Database	O95180 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
9AYG	EM	3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	2116		Mutation	No
9AYH	EM	3.1 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	2116		Mutation	No
9AYJ	EM	3.2 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	2116		Mutation	No
9AYK	EM	3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	2116		Mutation	No
9AYL	EM	2.8 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	2116		Mutation	No
References
1	Structural basis for human Ca(v)3.2 inhibition by selective antagonists. Cell Res. 2024;34(6):440-450.

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