General Information of Drug Transporter (DT)
DT ID	DTD0384 Transporter Info
Gene Name	SLC4A3
Transporter Name	Anion exchange protein 3
Gene ID	6508
UniProt ID	P48751
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	4YZF_A		Identity	55.773%
Performance	Minimized Score	-1810.804 kcal/mol
	Ramachandra Favored	Medium
	QMEANBrane Quality	Medium
Ramachandran Plot
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	Ramz Z Score	-0.76 ±0.26
	Residues in Favored Region	873	Ramachandran favored	95.72%
	Number of Outliers	7	Ramachandran outliers	0.77%
Local Quality
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	QMEANBrane Score		0.75
AlphaFold Protein Structure Database	P48751 Click to jump to the details page
SWISS-MODEL Database	P48751 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
8Y85	EM	2.73 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	1232		Mutation	No
8Y86	EM	2.75 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	1232		Mutation	No
8Y8K	EM	2.89 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	1232		Mutation	No
References
1	The structural insight into the functional modulation of human anion exchanger 3. Nat Commun. 2024;15(1):6134.

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