Detail Information of DT Wildtype Structure
| General Information of Drug Transporter (DT) | ||||||
|---|---|---|---|---|---|---|
| DT ID | DTD0267 Transporter Info | |||||
| Gene Name | SLC2A9 | |||||
| Transporter Name | Glucose transporter type 9 | |||||
| Gene ID | ||||||
| UniProt ID | ||||||
| Modelled Structures of This DT | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Detail Information of Structural Model | ||||||
| Method | Homology modeling | |||||
| Template PDB | 4YBQ_A | Identity | 45.148% | |||
| Performance | Minimized Score | -1232.895 kcal/mol | ||||
| Ramachandra Favored | Excellent |
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| QMEANBrane Quality | High |
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| Ramachandran Plot |
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| Click to Save Ramachandran Plot in PNG Format | ||||||
| Ramz Z Score | -0.84 ±0.34 | |||||
| Residues in Favored Region | 462 | Ramachandran favored | 98.51% | |||
| Number of Outliers | 2 | Ramachandran outliers | 0.43% | |||
| Local Quality |
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| Click to Save Local Quality Plot in PNG Format | ||||||
| QMEANBrane Score | 0.83 | |||||
| AlphaFold Protein Structure Database | ||||||
| SWISS-MODEL Database | ||||||
| Experimental Structures of This DT | ||||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
| 8Y65 | EM | 3.51 Å | Homo sapiens | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 582 | Mutation | No | |||
| 8Y66 | EM | 3.28 Å | Homo sapiens | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 582 | Mutation | No | |||
| References | ||||||
| 1 | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun. 2024;15(1):5039. | |||||
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