Detail Information of DT Wildtype Structure
General Information of Drug Transporter (DT) | ||||||
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DT ID | DTD0267 Transporter Info | |||||
Gene Name | SLC2A9 | |||||
Transporter Name | Glucose transporter type 9 | |||||
Gene ID | ||||||
UniProt ID | ||||||
Modelled Structures of This DT | ||||||
Click to Save PDB File in TXT Format | ||||||
Detail Information of Structural Model | ||||||
Method | Homology modeling | |||||
Template PDB | 4YBQ_A | Identity | 45.148% | |||
Performance | Minimized Score | -1232.895 kcal/mol | ||||
Ramachandra Favored | Excellent |
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QMEANBrane Quality | High |
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Ramachandran Plot |
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Click to Save Ramachandran Plot in PNG Format | ||||||
Ramz Z Score | -0.84 ±0.34 | |||||
Residues in Favored Region | 462 | Ramachandran favored | 98.51% | |||
Number of Outliers | 2 | Ramachandran outliers | 0.43% | |||
Local Quality |
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Click to Save Local Quality Plot in PNG Format | ||||||
QMEANBrane Score | 0.83 | |||||
AlphaFold Protein Structure Database | ||||||
SWISS-MODEL Database | ||||||
Experimental Structures of This DT | ||||||
PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
8Y65 | EM | 3.51 Å | Homo sapiens | [1] | ||
Structure | ||||||
Click to Save PDB File in TXT Format | ||||||
Corresponding chain | A | |||||
Sequence Length | 582 | Mutation | No | |||
8Y66 | EM | 3.28 Å | Homo sapiens | [1] | ||
Structure | ||||||
Click to Save PDB File in TXT Format | ||||||
Corresponding chain | A | |||||
Sequence Length | 582 | Mutation | No | |||
References | ||||||
1 | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun. 2024;15(1):5039. | |||||
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