Detail Information of DT Wildtype Structure
| General Information of Drug Transporter (DT) | ||||||
|---|---|---|---|---|---|---|
| DT ID | DTD0262 Transporter Info | |||||
| Gene Name | SLC2A4 | |||||
| Transporter Name | Glucose transporter type 4, insulin-responsive | |||||
| Gene ID | ||||||
| UniProt ID | ||||||
| Modelled Structures of This DT | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Detail Information of Structural Model | ||||||
| Method | Homology modeling | |||||
| Template PDB | 5EQG_A | Identity | 65.253% | |||
| Performance | Minimized Score | -1345.831 kcal/mol | ||||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | High |
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| Ramachandran Plot |
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| Click to Save Ramachandran Plot in PNG Format | ||||||
| Ramz Z Score | -1.05 ±0.34 | |||||
| Residues in Favored Region | 481 | Ramachandran favored | 97.57% | |||
| Number of Outliers | 1 | Ramachandran outliers | 0.20% | |||
| Local Quality |
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| Click to Save Local Quality Plot in PNG Format | ||||||
| QMEANBrane Score | 0.82 | |||||
| AlphaFold Protein Structure Database | ||||||
| SWISS-MODEL Database | ||||||
| Experimental Structures of This DT | ||||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
| 7WSM | EM | 3.25 Å | Homo sapiens | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 520 | Mutation | No | |||
| 7WSN | EM | 3.31 Å | Homo sapiens | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 520 | Mutation | No | |||
| References | ||||||
| 1 | Cryo-EM structure of human glucose transporter GLUT4. Nat Commun. 2022;13(1):2671. | |||||
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