General Information of Drug Transporter (DT)
DT ID DTD0262 Transporter Info
Gene Name SLC2A4
Transporter Name Glucose transporter type 4, insulin-responsive
Gene ID
6517
UniProt ID
P14672
Modelled Structures of This DT
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Detail Information of Structural Model
Method Homology modeling
Template PDB 5EQG_A Identity 65.253%
Performance Minimized Score -1345.831 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

High

Ramachandran Plot
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Ramz Z Score -1.05 ±0.34
Residues in Favored Region 481 Ramachandran favored 97.57%
Number of Outliers 1 Ramachandran outliers 0.20%
Local Quality
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QMEANBrane Score 0.82
AlphaFold Protein Structure Database
SWISS-MODEL Database
Experimental Structures of This DT
PDB ID Scanning Method Resolution Expression System Details Ref
7WSM EM 3.25 Å Homo sapiens
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[1]
Structure
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Corresponding chain A
Sequence Length 520 Mutation No
7WSN EM 3.31 Å Homo sapiens
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[1]
Structure
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Corresponding chain A
Sequence Length 520 Mutation No
References
1 Cryo-EM structure of human glucose transporter GLUT4. Nat Commun. 2022;13(1):2671.

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