Detail Information of DT Wildtype Structure
General Information of Drug Transporter (DT) | ||||||
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DT ID | DTD0262 Transporter Info | |||||
Gene Name | SLC2A4 | |||||
Transporter Name | Glucose transporter type 4, insulin-responsive | |||||
Gene ID | ||||||
UniProt ID | ||||||
Modelled Structures of This DT | ||||||
Click to Save PDB File in TXT Format | ||||||
Detail Information of Structural Model | ||||||
Method | Homology modeling | |||||
Template PDB | 5EQG_A | Identity | 65.253% | |||
Performance | Minimized Score | -1345.831 kcal/mol | ||||
Ramachandra Favored | Medium |
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QMEANBrane Quality | High |
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Ramachandran Plot |
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Click to Save Ramachandran Plot in PNG Format | ||||||
Ramz Z Score | -1.05 ±0.34 | |||||
Residues in Favored Region | 481 | Ramachandran favored | 97.57% | |||
Number of Outliers | 1 | Ramachandran outliers | 0.20% | |||
Local Quality |
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Click to Save Local Quality Plot in PNG Format | ||||||
QMEANBrane Score | 0.82 | |||||
AlphaFold Protein Structure Database | ||||||
SWISS-MODEL Database | ||||||
Experimental Structures of This DT | ||||||
PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
7WSM | EM | 3.25 Å | Homo sapiens | [1] | ||
Structure | ||||||
Click to Save PDB File in TXT Format | ||||||
Corresponding chain | A | |||||
Sequence Length | 520 | Mutation | No | |||
7WSN | EM | 3.31 Å | Homo sapiens | [1] | ||
Structure | ||||||
Click to Save PDB File in TXT Format | ||||||
Corresponding chain | A | |||||
Sequence Length | 520 | Mutation | No | |||
References | ||||||
1 | Cryo-EM structure of human glucose transporter GLUT4. Nat Commun. 2022;13(1):2671. | |||||
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