Detail Information of DT Wildtype Structure
| General Information of Drug Transporter (DT) | ||||||
|---|---|---|---|---|---|---|
| DT ID | DTD0124 Transporter Info | |||||
| Gene Name | SLC18A3 | |||||
| Transporter Name | Vesicular acetylcholine transporter | |||||
| Gene ID | ||||||
| UniProt ID | ||||||
| Experimental Structures of This DT | ||||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
| 8XTW | EM | 3.3 Å | Homo sapiens | |||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 27-478 | Mutation | No | |||
| 8XTX | EM | 3.4 Å | Homo sapiens | |||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 27-478 | Mutation | No | |||
| 8XTY | EM | 2.7 Å | Homo sapiens | |||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 27-478 | Mutation | No | |||
| 8ZMR | EM | 3.5 Å | Homo sapiens | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 34-524 | Mutation | No | |||
| 8ZMS | EM | 3.7 Å | Homo sapiens | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A | |||||
| Sequence Length | 34-524 | Mutation | No | |||
| Modelled Structures of This DT | ||||||
| Click to Save PDB File in PDB Format | ||||||
| Detail Information of Modelled Structures | ||||||
| Method | multi-sequence alignment based machine learning | |||||
| AlphaFold Protein Structure Database | ||||||
| References | ||||||
| 1 | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res. 2024;34(9):665-668. | |||||
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