Detail Information of DT Wildtype Structure
| General Information of Drug Transporter (DT) | ||||||
|---|---|---|---|---|---|---|
| DT ID | DTD0123 Transporter Info | |||||
| Gene Name | SLC18A1 | |||||
| Transporter Name | Vesicular amine transporter 1 | |||||
| Gene ID | ||||||
| UniProt ID | ||||||
| Experimental Structures of This DT | ||||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
| 8TGG | EM | 3.6 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGH | EM | 3.5 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGI | EM | 3.4 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGJ | EM | 3.5 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGK | EM | 3.7 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGL | EM | 3.4 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGM | EM | 3.5 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| 8TGN | EM | 3.3 Å | Komagataella Pastoris | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Corresponding chain | A/B | |||||
| Sequence Length | 470 | Mutation | No | |||
| Modelled Structures of This DT | ||||||
| Click to Save PDB File in PDB Format | ||||||
| Detail Information of Modelled Structures | ||||||
| Method | multi-sequence alignment based machine learning | |||||
| AlphaFold Protein Structure Database | ||||||
| References | ||||||
| 1 | Structural insights into vesicular monoamine storage and drug interactions. Nature. 2024;629(8010):235-243. | |||||
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