General Information of Drug Transporter (DT)
DT ID	DTD0095 Transporter Info
Gene Name	SLC13A5
Transporter Name	Sodium-coupled citrate transporter
Gene ID	284111
UniProt ID	Q86YT5
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	3REF_A; 3W8R_A; 5ULD_A		Identity	59.091; 36.364; 32.80%
Ramachandran Plot
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	Ramz Z Score	-1.81 ±0.34
	Residues in Favored Region	459	Ramachandran favored	94.06%
	Number of Outliers	7	Ramachandran outliers	1.43%
Local Quality
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	QMEANBrane Score		0.75
AlphaFold Protein Structure Database	Q86YT5 Click to jump to the details page
SWISS-MODEL Database	Q86YT5 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
7JSJ	EM	3.12 Å	Trichoplusia Ni	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	568		Mutation	No
7JSK	EM	3.04 Å	Trichoplusia Ni	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	568		Mutation	No
8UVB	EM	2.13 Å	Trichoplusia Ni	Click to Show/Hide the Details	[2]
Structure
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Corresponding chain	A/B
Sequence Length	568		Mutation	No
8UVH	EM	2.33 Å	Trichoplusia Ni	Click to Show/Hide the Details	[2]
Structure
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Corresponding chain	A/B
Sequence Length	568		Mutation	No
References
1	Structure and inhibition mechanism of the human citrate transporter NaCT. Nature. 2021;591(7848):157-161.
2	Substrate translocation and inhibition in human dicarboxylate transporter NaDC3. Nat Struct Mol Biol. 2025 Mar;32(3):502-512.

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