Drug Transporter (DT) Information

General Information of DT
DT ID DTD0498
Gene Name SLC9C2
Protein Name Sodium/hydrogen exchanger 11
Gene ID
284525
UniProt ID
Q5TAH2
TCDB ID
2.A.36.7.4
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms NHE-11; Na(+)/H(+) exchanger 11; SLC9A11; SLC9C2; Solute carrier family 9 member 11; Solute carrier family 9 member C2
DT Family Monovalent Cation:Proton Antiporter-1 (CPA1) family ;
Function This transporter mediates pH regulation.
Endogenous Substrate(s) Na+; H+
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Sodium/hydrogen exchanger 11
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Sodium/hydrogen exchanger 11
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Sodium/hydrogen exchanger 11
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Sodium/hydrogen exchanger 11
Post-translational Modification (PTM)

(δ) Epigenetic Regulation of Sodium/hydrogen exchanger 11
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Sodium/hydrogen exchanger 11
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Sodium/hydrogen exchanger 11
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Sodium/hydrogen exchanger 11
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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