Modelled DT Structure
Method: multi-sequence alignment based machine learning
Detail: Structure Info
| General Information of DT | |||||
|---|---|---|---|---|---|
| DT ID | DTD0148 | ||||
| Gene Name | SLC22A25 | ||||
| Protein Name | Organic anion transporter UST6 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method: multi-sequence alignment based machine learning Detail: Structure Info |
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| Synonyms | HIMTP; SLC22A25; Solute carrier family 22 member 25; UST6 | ||||
| DT Family | Major Facilitator Superfamily (MFS) | ||||
| Organic Cation Transporter (OCT) Family | |||||
| Tissue Specificity | Expressed exclusively in liver in both embryoand adult. | ||||
| Function | Act as an organic anion and cation transporter. | ||||
| Endogenous Substrate(s) | Organic anions | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Organic anion transporter UST6 |
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(β) Cell Distribution Level of Organic anion transporter UST6 |
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(γ) Organelle Distribution Level of Organic anion transporter UST6 |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of Organic anion transporter UST6 |
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(δ) Epigenetic Regulation of Organic anion transporter UST6 |
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(ε) Exogenous Modulation of Organic anion transporter UST6 |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Organic anion transporter UST6 |
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(β) Disease-specific Protein Abundances of Organic anion transporter UST6 |
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(γ) Species- and Tissue-specific DT Abundances |
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