Drug Transporter (DT) Information

General Information of DT
DT ID DTD0373
Gene Name SLC46A2
Protein Name Thymic stromal cotransporter homolog
Gene ID
57864
UniProt ID
Q9BY10
TCDB ID
2.A.1.50.2
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms Ly110; SLC46A2; Solute carrier family 46 member 2; TSCOT
DT Family Major Facilitator Superfamily (MFS)
Proton Coupled Folate Transporter/Heme Carrier Protein (PCFT/HCP) Family
Tissue Specificity Strongly expressed in the adult thymus.Expressed in spleen, lymph nodes, thymus, PBL, bone marrow andfetal liver.
Function Act as a cation transporter.
Endogenous Substrate(s) Cations
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Thymic stromal cotransporter homolog
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Thymic stromal cotransporter homolog
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Thymic stromal cotransporter homolog
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Thymic stromal cotransporter homolog
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Thymic stromal cotransporter homolog
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Thymic stromal cotransporter homolog
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Thymic stromal cotransporter homolog
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Thymic stromal cotransporter homolog
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Thymic stromal cotransporter homolog
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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