Drug Transporter (DT) Information

General Information of DT
DT ID DTD0311
Gene Name SLC35F6
Protein Name ANT2-binding protein
Gene ID
54978
UniProt ID
Q8N357
TCDB ID
2.A.7.12.13
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms ANT2BP; C2orf18; SLC35F6; Solute carrier family 35 member F6; TANGO9; Transport and Golgi organization 9 homolog; UNQ3047/PRO9863
DT Family Drug/Metabolite Transporter (DMT) Superfamily
CMP-Sialate:CMP Antiporter (CSA) Family
Tissue Specificity Expressed in pancreatic ductal adenocarcinoma(PDAC) (at protein level). Strongly expressed in prostate andthyroid. Weakly expressed in lung, heart, liver and kidney.
Function This transporter is involved in maintaining mitochondrial membrane potential of pancreatic ductal adenocarcinoma (PDAC) cells. Promote the growth of pancreatic ductal adenocarcinoma (PDAC) cells. May play the role of nucleotide sugar transporter.
Endogenous Substrate(s) Nucleotide-sugar
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of ANT2-binding protein
Tissue Distribution Level (TD)

(β) Cell Distribution Level of ANT2-binding protein
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of ANT2-binding protein
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of ANT2-binding protein
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of ANT2-binding protein
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of ANT2-binding protein
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of ANT2-binding protein
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of ANT2-binding protein
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of ANT2-binding protein
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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