Drug Transporter (DT) Information

General Information of DT
DT ID DTD0044
Gene Name ABCA6
Protein Name ATP-binding cassette sub-family A member 6
Gene ID
23460
UniProt ID
Q8N139
TCDB ID
3.A.1.211.15
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms ABCA6; EST155051; ATP-binding cassette A member 6
DT Family ATP-Binding Cassette (ABC) Superfamily ;
Tissue Specificity Widely expressed with higher expression inliver.
Function This transporter is probable transporter which may play a role in macrophage lipid homeostasis.
Endogenous Substrate(s) Lipids
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of ATP-binding cassette sub-family A member 6
Tissue Distribution Level (TD)

(β) Cell Distribution Level of ATP-binding cassette sub-family A member 6
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of ATP-binding cassette sub-family A member 6
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of ATP-binding cassette sub-family A member 6
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of ATP-binding cassette sub-family A member 6
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of ATP-binding cassette sub-family A member 6
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of ATP-binding cassette sub-family A member 6
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of ATP-binding cassette sub-family A member 6
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of ATP-binding cassette sub-family A member 6
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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