Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0535 Transporter Info
Gene Name	CACNB2
Transporter Name	Voltage-dependent L-type calcium channel beta-2
Gene ID	783
UniProt ID	Q08289

Post-Translational Modification of This DT
Overview ofCACNB2 Modification Sites with Functional and Structural Information
Sequence	M V Q R D M S K S P P T A A A A V A Q E I Q M E L L E N V A P A G A L G A A A Q S Y G K G A R R K N R F K G S D G S T S S D T T S N S F V R Q G S A D S Y T S R P S D S D V S L E E D R E A V R R E A E R Q A Q A Q L E K A K T K P V A F A V R T N V S Y S A A H E D D V P V P G M A I S F E A K D F L H V K E K F N N D W W I G R L V K E G C E I G F I P S P V K L E N M R L Q H E Q R A K Q G K F Y S S K S G G N S S S S L G D I V P S S R K S T P P S S A I D I D A T G L D A E E N D I P A N H R S P K P S A N S V T S P H S K E K R M P F F K K T E H T P P Y D V V P S M R P V V L V G P S L K G Y E V T D M M Q K A L F D F L K H R F E G R I S I T R V T A D I S L A K R S V L N N P S K H A I I E R S N T R S S L A E V Q S E I E R I F E L A R T L Q L V V L D A D T I N H P A Q L S K T S L A P I I V Y V K I S S P K V L Q R L I K S R G K S Q A K H L N V Q M V A A D K L A Q C P P E L F D V I L D E N Q L E D A C E H L A D Y L E A Y W K A T H P P S S S L P N P L L S R T L A T S S L P L S P T L A S N S Q G S Q G D Q R T D R S A P I R S A S Q A E E E P S V E P V K K S Q H R S S S S A P H H N H R S G T S R G L S R Q E T F D S E T Q E S R D S A Y V E P K E D Y S H D H V D H Y A S H R D H N H R D E T H G S S D H R H R E S R H R S R D V D R E Q D H N E C N K Q R S R H K S K D R Y C E K D G E V I S K K R N E A G E W N R D V Y I R Q
PTM type	X-O-glycosylation X-Oxidation X-Phosphorylation X: Amino Acid

O-glycosylation
Serine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence CACNB2			[1]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	550
Experimental Method	Co-Immunoprecipitation
Detailed Description	O-linked Glycosylation at CACNB2 Serine 550 has the potential to affect its expression or activity.
Oxidation
Cystine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence CACNB2			[2]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	168
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at CACNB2 Cystine 168 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence CACNB2			[3]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	432
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at CACNB2 Cystine 432 has the potential to affect its expression or activity.
Phosphorylation
Serine	42 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence CACNB2			[4]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	58
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 58 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence CACNB2			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	60
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 60 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence CACNB2			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	61
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 61 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence CACNB2			[6], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	73
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 73 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence CACNB2			[6], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	76
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 76 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence CACNB2			[6], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	79
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 79 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence CACNB2			[6], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	82
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 82 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence CACNB2			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	84
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 84 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence CACNB2			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	87
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 87 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence CACNB2			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	207
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 207 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence CACNB2			[7], [9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	218
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 218 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence CACNB2			[7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	222
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 222 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence CACNB2			[5], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	223
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 223 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence CACNB2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	245
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 245 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence CACNB2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	249
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 249 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence CACNB2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	252
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 252 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence CACNB2			[11], [12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	255
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 255 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence CACNB2			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	258
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 258 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence CACNB2			[13], [14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	280
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 280 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence CACNB2			[13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	290
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 290 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence CACNB2			[4], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	317
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 317 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence CACNB2			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	326
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 326 has the potential to affect its expression or activity.
PTM Phenomenon23	Have the potential to influence CACNB2			[16], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	483
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 483 has the potential to affect its expression or activity.
PTM Phenomenon24	Have the potential to influence CACNB2			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	484
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 484 has the potential to affect its expression or activity.
PTM Phenomenon25	Have the potential to influence CACNB2			[9], [16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	488
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 488 has the potential to affect its expression or activity.
PTM Phenomenon26	Have the potential to influence CACNB2			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	493
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 493 has the potential to affect its expression or activity.
PTM Phenomenon27	Have the potential to influence CACNB2			[16], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	495
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 495 has the potential to affect its expression or activity.
PTM Phenomenon28	Have the potential to influence CACNB2			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	498
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 498 has the potential to affect its expression or activity.
PTM Phenomenon29	Have the potential to influence CACNB2			[18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	507
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 507 has the potential to affect its expression or activity.
PTM Phenomenon30	Have the potential to influence CACNB2			[18], [19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	512
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 512 has the potential to affect its expression or activity.
PTM Phenomenon31	Have the potential to influence CACNB2			[18], [19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	514
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 514 has the potential to affect its expression or activity.
PTM Phenomenon32	Have the potential to influence CACNB2			[8], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	521
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 521 has the potential to affect its expression or activity.
PTM Phenomenon33	Have the potential to influence CACNB2			[4], [6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	528
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 528 has the potential to affect its expression or activity.
PTM Phenomenon34	Have the potential to influence CACNB2			[6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	532
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 532 has the potential to affect its expression or activity.
PTM Phenomenon35	Have the potential to influence CACNB2			[6], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	533
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 533 has the potential to affect its expression or activity.
PTM Phenomenon36	Have the potential to influence CACNB2			[6], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	534
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 534 has the potential to affect its expression or activity.
PTM Phenomenon37	Have the potential to influence CACNB2			[6], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	535
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 535 has the potential to affect its expression or activity.
PTM Phenomenon38	Have the potential to influence CACNB2			[4], [6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	543
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 543 has the potential to affect its expression or activity.
PTM Phenomenon39	Have the potential to influence CACNB2			[4]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	546
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 546 has the potential to affect its expression or activity.
PTM Phenomenon40	Have the potential to influence CACNB2			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	575
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 575 has the potential to affect its expression or activity.
PTM Phenomenon41	Have the potential to influence CACNB2			[21]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	605
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 605 has the potential to affect its expression or activity.
PTM Phenomenon42	Have the potential to influence CACNB2			[6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	609
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Serine 609 has the potential to affect its expression or activity.
Threonine	13 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence CACNB2			[5]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	64
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 64 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence CACNB2			[6], [8]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	78
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 78 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence CACNB2			[22]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	121
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 121 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence CACNB2			[7], [9]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	219
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 219 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence CACNB2			[10]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	254
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 254 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence CACNB2			[23]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	269
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 269 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence CACNB2			[23], [24]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	272
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 272 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence CACNB2			[13]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	297
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 297 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence CACNB2			[8]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	319
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 319 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence CACNB2			[8], [15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	322
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 322 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence CACNB2			[16]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	482
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 482 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence CACNB2			[9], [16]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	490
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 490 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence CACNB2			[25]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	554
Related Enzyme	Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D)
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Threonine 554 has the potential to affect its expression or activity.
Tyrosine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence CACNB2			[6], [8]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	77
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Tyrosine 77 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence CACNB2			[13]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	294
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Tyrosine 294 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence CACNB2			[20]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	574
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at CACNB2 Tyrosine 574 has the potential to affect its expression or activity.

References
1	Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells. Nat Commun. 2019 Sep 6;10(1):4065.
2	A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. 2020 Mar 5;180(5):968-983.e24.
3	Comparative proteomic analysis of cysteine oxidation in colorectal cancer patients. Mol Cells. 2013 Jun;35(6):533-42.
4	Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics. 2014 Jul;13(7):1690-704.
5	Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nat Immunol. 2013 Nov;14(11):1166-72.
6	Defeating Major Contaminants in Fe3+- Immobilized Metal Ion Affinity Chromatography (IMAC) Phosphopeptide Enrichment. Mol Cell Proteomics. 2018 May;17(5):1028-1034.
7	Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. EMBO J. 2015 Nov 12;34(22):2840-61.
8	Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res. 2013 Jun 7;12(6):2414-21.
9	Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun. 2017 Mar 28;8:14864.
10	Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2918-27.
11	Protein kinase C-alpha interaction with F0F1-ATPase promotes F0F1-ATPase activity and reduces energy deficits in injured renal cells. J Biol Chem. 2015 Mar 13;290(11):7054-66.
12	Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep. 2014 Sep 11;8(5):1583-94.
13	An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics. 2014 Jan 16;96:253-62.
14	Sequential enrichment with titania-coated magnetic mesoporous hollow silica microspheres and zirconium arsenate-modified magnetic nanoparticles for the study of phosphoproteome of HL60 cells. J Chromatogr A. 2014 Oct 24;1365:54-60.
15	Tip-Based Fractionation of Batch-Enriched Phosphopeptides Facilitates Easy and Robust Phosphoproteome Analysis. J Proteome Res. 2018 Jan 5;17(1):46-54.
16	An integrated strategy for highly sensitive phosphoproteome analysis from low micrograms of protein samples. Analyst. 2018 Jul 23;143(15):3693-3701.
17	Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit. J Biol Chem. 1999 Nov 26;274(48):33851-4.
18	Phosphoproteomic and Functional Analyses Reveal Sperm-specific Protein Changes Downstream of Kappa Opioid Receptor in Human Spermatozoa. Mol Cell Proteomics. 2019 Mar 15;18(Suppl 1):S118-S131.
19	Modulation of Cl- signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT. Sci Signal. 2018 Oct 30;11(554):eaat5018.
20	Improve the coverage for the analysis of phosphoproteome of HeLa cells by a tandem digestion approach. J Proteome Res. 2012 May 4;11(5):2828-37.
21	The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016 Aug;15(8):2537-53.
22	Analysis of the subcellular phosphoproteome using a novel phosphoproteomic reactor. J Proteome Res. 2010 Mar 5;9(3):1279-88.
23	Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 2016 Jun 2;534(7605):55-62.
24	Integrated analysis of global proteome, phosphoproteome, and glycoproteome enables complementary interpretation of disease-related protein networks. Sci Rep. 2015 Dec 11;5:18189.
25	UniProt: the Universal Protein Knowledgebase in 2023. Nucleic Acids Res. 2023 Jan 6;51(D1):D523-D531. (ID: Q08289)

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.

Detail Information of Post-Translational Modifications

Visitor Map

Correspondence