Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0013 Transporter Info
Gene Name	ABCB4
Transporter Name	Multidrug resistance protein 3
Gene ID	5244
UniProt ID	P21439

Post-Translational Modification of This DT
Overview ofABCB4 Modification Sites with Functional and Structural Information
Sequence	M D L E A A K N G T A W R P T S A E G D F E L G I S S K Q K R K K T K T V K M I G V L T L F R Y S D W Q D K L F M S L G T I M A I A H G S G L P L M M I V F G E M T D K F V D T A G N F S F P V N F S L S L L N P G K I L E E E M T R Y A Y Y Y S G L G A G V L V A A Y I Q V S F W T L A A G R Q I R K I R Q K F F H A I L R Q E I G W F D I N D T T E L N T R L T D D I S K I S E G I G D K V G M F F Q A V A T F F A G F I V G F I R G W K L T L V I M A I S P I L G L S A A V W A K I L S A F S D K E L A A Y A K A G A V A E E A L G A I R T V I A F G G Q N K E L E R Y Q K H L E N A K E I G I K K A I S A N I S M G I A F L L I Y A S Y A L A F W Y G S T L V I S K E Y T I G N A M T V F F S I L I G A F S V G Q A A P C I D A F A N A R G A A Y V I F D I I D N N P K I D S F S E R G H K P D S I K G N L E F N D V H F S Y P S R A N V K I L K G L N L K V Q S G Q T V A L V G S S G C G K S T T V Q L I Q R L Y D P D E G T I N I D G Q D I R N F N V N Y L R E I I G V V S Q E P V L F S T T I A E N I C Y G R G N V T M D E I K K A V K E A N A Y E F I M K L P Q K F D T L V G E R G A Q L S G G Q K Q R I A I A R A L V R N P K I L L L D E A T S A L D T E S E A E V Q A A L D K A R E G R T T I V I A H R L S T V R N A D V I A G F E D G V I V E Q G S H S E L M K K E G V Y F K L V N M Q T S G S Q I Q S E E F E L N D E K A A T R M A P N G W K S R L F R H S T Q K N L K N S Q M C Q K S L D V E T D G L E A N V P P V S F L K V L K L N K T E W P Y F V V G T V C A I A N G G L Q P A F S V I F S E I I A I F G P G D D A V K Q Q K C N I F S L I F L F L G I I S F F T F F L Q G F T F G K A G E I L T R R L R S M A F K A M L R Q D M S W F D D H K N S T G A L S T R L A T D A A Q V Q G A T G T R L A L I A Q N I A N L G T G I I I S F I Y G W Q L T L L L L A V V P I I A V S G I V E M K L L A G N A K R D K K E L E A A G K I A T E A I E N I R T V V S L T Q E R K F E S M Y V E K L Y G P Y R N S V Q K A H I Y G I T F S I S Q A F M Y F S Y A G C F R F G A Y L I V N G H M R F R D V I L V F S A I V F G A V A L G H A S S F A P D Y A K A K L S A A H L F M L F E R Q P L I D S Y S E E G L K P D K F E G N I T F N E V V F N Y P T R A N V P V L Q G L S L E V K K G Q T L A L V G S S G C G K S T V V Q L L E R F Y D P L A G T V F V D F G F Q L L D G Q E A K K L N V Q W L R A Q L G I V S Q E P I L F D C S I A E N I A Y G D N S R V V S Q D E I V S A A K A A N I H P F I E T L P H K Y E T R V G D K G T Q L S G G Q K Q R I A I A R A L I R Q P Q I L L L D E A T S A L D T E S E K V V Q E A L D K A R E G R T C I V I A H R L S T I Q N A D L I V V F Q N G R V K E H G T H Q Q L L A Q K G I Y F S M V S V Q A G T Q N L
PTM type	X-Acetylation X-N-glycosylation X-Oxidation X-Phosphorylation X-Phosphorylation X-Ubiquitination X-Ubiquitination X: Amino Acid

Acetylation
Lysine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	679
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at ABCB4 Lysine 679 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCB4			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	699
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at ABCB4 Lysine 699 has the potential to affect its expression or activity.
N-glycosylation
Asparagine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[2]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	91
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCB4 Asparagine 91 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCB4			[2]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	97
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCB4 Asparagine 97 has the potential to affect its expression or activity.
Oxidation
Cystine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[3]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1073
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCB4 Cystine 1073 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCB4			[3]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1131
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCB4 Cystine 1131 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCB4			[3]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1233
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCB4 Cystine 1233 has the potential to affect its expression or activity.
Phosphorylation
Serine	20 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[4]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	49
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 49 has the potential to affect its expression or activity.
PTM Phenomenon2	.			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	69
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 69 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	69
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 69 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCB4			[2]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	121
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 121 has the potential to affect its expression or activity.
PTM Phenomenon5	.			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	296
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 296 has the potential to affect its expression or activity.
PTM Phenomenon6	.			[5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	300
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 300 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCB4			[6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	421
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 421 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCB4			[6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	430
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 430 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCB4			[6]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	431
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 431 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCB4			[7], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	592
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 592 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCB4			[9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	680
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 680 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence ABCB4			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	696
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 696 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence ABCB4			[11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	765
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 765 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCB4			[12], [13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	789
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 789 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence ABCB4			[14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	908
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 908 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence ABCB4			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1019
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 1019 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence ABCB4			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1021
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 1021 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence ABCB4			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1071
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 1071 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence ABCB4			[17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1275
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 1275 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence ABCB4			[17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1278
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Serine 1278 has the potential to affect its expression or activity.
Threonine	11 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Increasing the function of ABCB4			[4]
Role of PTM	Protein Activity Modulation
Affected Drug/Substrate	Phosphatidylcholine	Results for Drug	Increasing Phosphatidylcholine secretion
Modified Residue	Threonine	Modified Location	34
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 34 have been reported to increase its transport function.
PTM Phenomenon2	Have the potential to influence ABCB4			[4]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	44
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 44 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCB4			[6]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	424
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 424 has the potential to affect its expression or activity.
PTM Phenomenon4	.			[5]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	524
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 524 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCB4			[7], [8]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	593
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 593 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCB4			[11]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	768
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 768 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCB4			[11]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	784
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 784 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCB4			[14]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	905
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 905 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCB4			[14]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	910
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 910 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCB4			[17]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1262
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 1262 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCB4			[17]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1283
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Threonine 1283 has the potential to affect its expression or activity.
Tyrosine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[18]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	624
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Tyrosine 624 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCB4			[17]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1273
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCB4 Tyrosine 1273 has the potential to affect its expression or activity.
Ubiquitination
Alanine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Alanine	Modified Location	998
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Alanine 998 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Alanine	Modified Location	1191
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Alanine 1191 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCB4			[19], [20]
Role of PTM	Potential impacts
Modified Residue	Alanine	Modified Location	1211
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Alanine 1211 has the potential to affect its expression or activity.
Glutamicacid	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Glutamicacid	Modified Location	1172
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Glutamicacid 1172 has the potential to affect its expression or activity.
Glycine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Glycine	Modified Location	1179
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Glycine 1179 has the potential to affect its expression or activity.
Histidine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Histidine	Modified Location	1006
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Histidine 1006 has the potential to affect its expression or activity.
Isoleucine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19], [20]
Role of PTM	Potential impacts
Modified Residue	Isoleucine	Modified Location	1164
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Isoleucine 1164 has the potential to affect its expression or activity.
Lysine	15 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	281
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 281 has the potential to affect its expression or activity.
PTM Phenomenon2	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	507
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 507 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	507
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 507 has the potential to affect its expression or activity.
PTM Phenomenon4	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	517
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 517 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCB4			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	538
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 538 has the potential to affect its expression or activity.
PTM Phenomenon6	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	577
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 577 has the potential to affect its expression or activity.
PTM Phenomenon7	.			[21]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1061
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1061 has the potential to affect its expression or activity.
PTM Phenomenon8	.			[21]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1061
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1061 has the potential to affect its expression or activity.
PTM Phenomenon9	.			[21]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1061
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1061 has the potential to affect its expression or activity.
PTM Phenomenon10	.			[21]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1061
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1061 has the potential to affect its expression or activity.
PTM Phenomenon11	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1170
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1170 has the potential to affect its expression or activity.
PTM Phenomenon12	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1178
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1178 has the potential to affect its expression or activity.
PTM Phenomenon13	.			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1187
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1187 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCB4			[19], [20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1218
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1218 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1226
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Lysine 1226 has the potential to affect its expression or activity.
Serine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1183
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Serine 1183 has the potential to affect its expression or activity.
Tyrosine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1171
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Tyrosine 1171 has the potential to affect its expression or activity.
Valine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Valine	Modified Location	1175
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Valine 1175 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCB4			[19]
Role of PTM	Potential impacts
Modified Residue	Valine	Modified Location	1219
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCB4 Valine 1219 has the potential to affect its expression or activity.

References
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