Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0385 Transporter Info
Gene Name	SLC4A4
Transporter Name	Electrogenic sodium bicarbonate cotransporter 1
Gene ID	8671
UniProt ID	Q9Y6R1

Post-Translational Modification of This DT
Overview ofSLC4A4 Modification Sites with Functional and Structural Information
Sequence	M E D E A V L D R G A S F L K H V C D E E E V E G H H T I Y I G V H V P K S Y R R R R R H K R K T G H K E K K E K E R I S E N Y S D K S D I E N A D E S S S S I L K P L I S P A A E R I R F I L G E E D D S P A P P Q L F T E L D E L L A V D G Q E M E W K E T A R W I K F E E K V E Q G G E R W S K P H V A T L S L H S L F E L R T C M E K G S I M L D R E A S S L P Q L V E M I V D H Q I E T G L L K P E L K D K V T Y T L L R K H R H Q T K K S N L R S L A D I G K T V S S A S R M F T N P D N G S P A M T H R N L T S S S L N D I S D K P E K D Q L K N K F M K K L P R D A E A S N V L V G E V D F L D T P F I A F V R L Q Q A V M L G A L T E V P V P T R F L F I L L G P K G K A K S Y H E I G R A I A T L M S D E V F H D I A Y K A K D R H D L I A G I D E F L D E V I V L P P G E W D P A I R I E P P K S L P S S D K R K N M Y S G G E N V Q M N G D T P H D G G H G G G G H G D C E E L Q R T G R F C G G L I K D I K R K A P F F A S D F Y D A L N I Q A L S A I L F I Y L A T V T N A I T F G G L L G D A T D N M Q G V L E S F L G T A V S G A I F C L F A G Q P L T I L S S T G P V L V F E R L L F N F S K D N N F D Y L E F R L W I G L W S A F L C L I L V A T D A S F L V Q Y F T R F T E E G F S S L I S F I F I Y D A F K K M I K L A D Y Y P I N S N F K V G Y N T L F S C T C V P P D P A N I S I S N D T T L A P E Y L P T M S S T D M Y H N T T F D W A F L S K K E C S K Y G G N L V G N N C N F V P D I T L M S F I L F L G T Y T S S M A L K K F K T S P Y F P T T A R K L I S D F A I I L S I L I F C V I D A L V G V D T P K L I V P S E F K P T S P N R G W F V P P F G E N P W W V C L A A A I P A L L V T I L I F M D Q Q I T A V I V N R K E H K L K K G A G Y H L D L F W V A I L M V I C S L M A L P W Y V A A T V I S I A H I D S L K M E T E T S A P G E Q P K F L G V R E Q R V T G T L V F I L T G L S V F M A P I L K F I P M P V L Y G V F L Y M G V A S L N G V Q F M D R L K L L L M P L K H Q P D F I Y L R H V P L R R V H L F T F L Q V L C L A L L W I L K S T V A A I I F P V M I L A L V A V R K G M D Y L F S Q H D L S F L D D V I P E K D K K K K E D E K K K K K K K G S L D S D N D D S D C P Y S E K V P S I K I P M D I M E Q Q P F L S D S K P S D R E R S P T F L E R H T S C
PTM type	X-Acetylation X-Disulfide bond X-N-glycosylation X-Oxidation X-Phosphorylation X-Ubiquitination X: Amino Acid

Acetylation
Lysine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A4			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	167
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC4A4 Lysine 167 has the potential to affect its expression or activity.
Disulfide bond
Cystine	4 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A4			[2]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	627
Experimental Method	Co-Immunoprecipitation
Detailed Description	Disulfide bond (-SSR) at SLC4A4 Cystine 627 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A4			[2]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	629
Experimental Method	Co-Immunoprecipitation
Detailed Description	Disulfide bond (-SSR) at SLC4A4 Cystine 629 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A4			[2]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	674
Experimental Method	Co-Immunoprecipitation
Detailed Description	Disulfide bond (-SSR) at SLC4A4 Cystine 674 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A4			[2]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	686
Experimental Method	Co-Immunoprecipitation
Detailed Description	Disulfide bond (-SSR) at SLC4A4 Cystine 686 has the potential to affect its expression or activity.
N-glycosylation
Asparagine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A4			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	641
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A4 Asparagine 641 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A4			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	661
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at SLC4A4 Asparagine 661 has the potential to affect its expression or activity.
Oxidation
Cystine	4 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A4			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	18
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC4A4 Cystine 18 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A4			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	433
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC4A4 Cystine 433 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A4			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	443
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC4A4 Cystine 443 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A4			[4]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1036
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC4A4 Cystine 1036 has the potential to affect its expression or activity.
Phosphorylation
Serine	40 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Regulating of the stoichiometry of the membrane transporter			[5]
Role of PTM	Properties Modulation
Affected Drug/Substrate	Sodium and Bicarbonate	Results for Drug	Regulating the uptake of sodium and bicarbonate
Modified Residue	Serine	Modified Location	1026
Related Enzyme	cAMP-dependent protein kinase catalytic subunit alpha (PRKACA)
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1026 have been reported to cause a shift in the direction of basolateral membrane sodium bicarbonate transport from efflux to influx.
PTM Phenomenon2	Have the potential to influence SLC4A4			[6], [7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	12
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 12 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A4			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	38
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 38 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A4			[6], [9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	61
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 61 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A4			[6], [9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	65
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 65 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	68
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 68 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A4			[6], [11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	76
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 76 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A4			[6], [11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	77
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 77 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A4			[6], [11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	78
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 78 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A4			[6], [11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	79
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 79 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A4			[6], [11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	86
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 86 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC4A4			[12], [13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	219
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 219 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	223
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 223 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	232
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 232 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	233
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 233 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	235
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 235 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	245
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 245 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	255
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 255 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence SLC4A4			[10], [14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	256
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 256 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence SLC4A4			[10], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 257 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	262
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 262 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence SLC4A4			[16]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	396
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 396 has the potential to affect its expression or activity.
PTM Phenomenon23	Have the potential to influence SLC4A4			[17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	399
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 399 has the potential to affect its expression or activity.
PTM Phenomenon24	Have the potential to influence SLC4A4			[17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	400
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 400 has the potential to affect its expression or activity.
PTM Phenomenon25	Have the potential to influence SLC4A4			[18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	543
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 543 has the potential to affect its expression or activity.
PTM Phenomenon26	Have the potential to influence SLC4A4			[12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	675
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 675 has the potential to affect its expression or activity.
PTM Phenomenon27	Have the potential to influence SLC4A4			[12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	696
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 696 has the potential to affect its expression or activity.
PTM Phenomenon28	Have the potential to influence SLC4A4			[10]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	706
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 706 has the potential to affect its expression or activity.
PTM Phenomenon29	Have the potential to influence SLC4A4			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	716
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 716 has the potential to affect its expression or activity.
PTM Phenomenon30	Have the potential to influence SLC4A4			[13], [19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	995
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 995 has the potential to affect its expression or activity.
PTM Phenomenon31	Have the potential to influence SLC4A4			[13], [19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1000
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1000 has the potential to affect its expression or activity.
PTM Phenomenon32	Have the potential to influence SLC4A4			[6], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1029
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1029 has the potential to affect its expression or activity.
PTM Phenomenon33	Have the potential to influence SLC4A4			[6], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1034
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1034 has the potential to affect its expression or activity.
PTM Phenomenon34	Have the potential to influence SLC4A4			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1039
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1039 has the potential to affect its expression or activity.
PTM Phenomenon35	Have the potential to influence SLC4A4			[8], [12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1044
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1044 has the potential to affect its expression or activity.
PTM Phenomenon36	Have the potential to influence SLC4A4			[8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1059
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1059 has the potential to affect its expression or activity.
PTM Phenomenon37	Have the potential to influence SLC4A4			[8], [21]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1061
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1061 has the potential to affect its expression or activity.
PTM Phenomenon38	Have the potential to influence SLC4A4			[6], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1064
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1064 has the potential to affect its expression or activity.
PTM Phenomenon39	Have the potential to influence SLC4A4			[6], [22]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1069
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1069 has the potential to affect its expression or activity.
PTM Phenomenon40	Have the potential to influence SLC4A4			[23], [24]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1078
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Serine 1078 has the potential to affect its expression or activity.
Threonine	12 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A4			[15], [25]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	49
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 49 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A4			[26]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	163
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 163 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A4			[25], [27]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	207
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 207 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A4			[12], [28]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	230
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 230 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A4			[10], [29]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	239
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 239 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A4			[11], [29]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	249
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 249 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A4			[10], [15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	254
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 254 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A4			[12]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	693
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 693 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A4			[10]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	705
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 705 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC4A4			[8]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	715
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 715 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC4A4			[6], [11]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1071
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 1071 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC4A4			[23]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1077
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Threonine 1077 has the potential to affect its expression or activity.
Tyrosine	9 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC4A4			[30], [31]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	30
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 30 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC4A4			[8]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	39
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 39 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC4A4			[6], [10]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	64
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 64 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC4A4			[27]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	206
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 206 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC4A4			[12]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	677
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 677 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC4A4			[10]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	704
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 704 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC4A4			[8]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	718
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 718 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC4A4			[19]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	992
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 992 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC4A4			[12], [13]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1038
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC4A4 Tyrosine 1038 has the potential to affect its expression or activity.
Ubiquitination
Lysine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	.			[32]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	229
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC4A4 Lysine 229 has the potential to affect its expression or activity.

References
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