Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0040 Transporter Info
Gene Name	ABCA2
Transporter Name	ATP-binding cassette sub-family A member 2
Gene ID	20
UniProt ID	Q9BZC7

Post-Translational Modification of This DT
Overview ofABCA2 Modification Sites with Functional and Structural Information
Sequence	M G F L H Q L Q L L L W K N V T L K R R S P W V L A F E I F I P L V L F F I L L G L R Q K K P T I S V K E A F Y T A A P L T S A G I L P V M Q S L C P D G Q R D E F G F L Q Y A N S T V T Q L L E R L D R V V E E G N L F D P A R P S L G S E L E A L R Q H L E A L S A G P G T S G S H L D R S T V S S F S L D S V A R N P Q E L W R F L T Q N L S L P N S T A Q A L L A A R V D P P E V Y H L L F G P S S A L D S Q S G L H K G Q E P W S R L G G N P L F R M E E L L L A P A L L E Q L T C T P G S G E L G R I L T V P E S Q K G A L Q G Y R D A V C S G Q A A A R A R R F S G L S A E L R N Q L D V A K V S Q Q L G L D A P N G S D S S P Q A P P P R R L Q A L L G D L L D A Q K V L Q D V D V L S A L A L L L P Q G A C T G R T P G P P A S G A G G A A N G T G A G A V M G P N A T A E E G A P S A A A L A T P D T L Q G Q C S A F V Q L W A G L Q P I L C G N N R T I E P E A L R R G N M S S L G F T S K E Q R N L G L L V H L M T S N P K I L Y A P A G S E V D R V I L K A N E T F A F V G N V T H Y A Q V W L N I S A E I R S F L E Q G R L Q Q H L R W L Q Q Y V A E L R L H P E A L N L S L D E L P P A L R Q D N F S L P S G M A L L Q Q L D T I D N A A C G W I Q F M S K V S V D I F K G F P D E E S I V N Y T L N Q A Y Q D N V T V F A S V I F Q T R K D G S L P P H V H Y K I R Q N S S F T E K T N E I R R A Y W R P G P N T G G R F Y F L Y G F V W I Q D M M E R A I I D T F V G H D V V E P G S Y V Q M F P Y P C Y T R D D F L F V I E H M M P L C M V I S W V Y S V A M T I Q H I V A E K E H R L K E V M K T M G L N N A V H W V A W F I T G F V Q L S I S V T A L T A I L K Y G Q V L M H S H V V I I W L F L A V Y A V A T I M F C F L V S V L Y S K A K L A S A C G G I I Y F L S Y V P Y M Y V A I R E E V A H D K I T A F E K C I A S L M S T T A F G L G S K Y F A L Y E V A G V G I Q W H T F S Q S P V E G D D F N L L L A V T M L M V D A V V Y G I L T W Y I E A V H P G M Y G L P R P W Y F P L Q K S Y W L G S G R T E A W E W S W P W A R T P R L S V M E E D Q A C A M E S R R F E E T R G M E E E P T H L P L V V C V D K L T K V Y K D D K K L A L N K L S L N L Y E N Q V V S F L G H N G A G K T T T M S I L T G L F P P T S G S A T I Y G H D I R T E M D E I R K N L G M C P Q H N V L F D R L T V E E H L W F Y S R L K S M A Q E E I R R E M D K M I E D L E L S N K R H S L V Q T L S G G M K R K L S V A I A F V G G S R A I I L D E P T A G V D P Y A R R A I W D L I L K Y K P G R T I L L S T H H M D E A D L L G D R I A I I S H G K L K C C G S P L F L K G T Y G D G Y R L T L V K R P A E P G G P Q E P G L A S S P P G R A P L S S C S E L Q V S Q F I R K H V A S C L L V S D T S T E L S Y I L P S E A A K K G A F E R L F Q H L E R S L D A L H L S S F G L M D T T L E E V F L K V S E E D Q S L E N S E A D V K E S R K D V L P G A E G P A S G E G H A G N L A R C S E L T Q S Q A S L Q S A S S V G S A R G D E G A G Y T D V Y G D Y R P L F D N P Q D P D N V S L Q E V E A E A L S R V G Q G S R K L D G G W L K V R Q F H G L L V K R F H C A R R N S K A L F S Q I L L P A F F V C V A M T V A L S V P E I G D L P P L V L S P S Q Y H N Y T Q P R G N F I P Y A N E E R R E Y R L R L S P D A S P Q Q L V S T F R L P S G V G A T C V L K S P A N G S L G P T L N L S S G E S R L L A A R F F D S M C L E S F T Q G L P L S N F V P P P P S P A P S D S P A S P D E D L Q A W N V S L P P T A G P E M W T S A P S L P R L V R E P V R C T C S A Q G T G F S C P S S V G G H P P Q M R V V T G D I L T D I T G H N V S E Y L L F T S D R F R L H R Y G A I T F G N V L K S I P A S F G T R A P P M V R K I A V R R A A Q V F Y N N K G Y H S M P T Y L N S L N N A I L R A N L P K S K G N P A A Y G I T V T N H P M N K T S A S L S L D Y L L Q G T D V V I A I F I I V A M S F V P A S F V V F L V A E K S T K A K H L Q F V S G C N P I I Y W L A N Y V W D M L N Y L V P A T C C V I I L F V F D L P A Y T S P T N F P A V L S L F L L Y G W S I T P I M Y P A S F W F E V P S S A Y V F L I V I N L F I G I T A T V A T F L L Q L F E H D K D L K V V N S Y L K S C F L I F P N Y N L G H G L M E M A Y N E Y I N E Y Y A K I G Q F D K M K S P F E W D I V T R G L V A M A V E G V V G F L L T I M C Q Y N F L R R P Q R M P V S T K P V E D D V D V A S E R Q R V L R G D A D N D M V K I E N L T K V Y K S R K I G R I L A V D R L C L G V R P G E C F G L L G V N G A G K T S T F K M L T G D E S T T G G E A F V N G H S V L K E L L Q V Q Q S L G Y C P Q C D A L F D E L T A R E H L Q L Y T R L R G I S W K D E A R V V K W A L E K L E L T K Y A D K P A G T Y S G G N K R K L S T A I A L I G Y P A F I F L D E P T T G M D P K A R R F L W N L I L D L I K T G R S V V L T S H S M E E C E A L C T R L A I M V N G R L R C L G S I Q H L K N R F G D G Y M I T V R T K S S Q S V K D V V R F F N R N F P E A M L K E R H H T K V Q Y Q L K S E H I S L A Q V F S K M E Q V S G V L G I E D Y S V S Q T T L D N V F V N F A K K Q S D N L E Q Q E T E P P S A L Q S P L G C L L S L L R P R S A P T E L R A L V A D E P E D L D T E D E G L I S F E E E R A Q L S F N T D T L C
PTM type	X-Acetylation X-Methylation X-N-glycosylation X-O-glycosylation X-Oxidation X-Phosphorylation X-Phosphorylation X-S-nitrosylation X-Ubiquitination X-Ubiquitination X: Amino Acid

Acetylation
Lysine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[1]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1167
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at ABCA2 Lysine 1167 has the potential to affect its expression or activity.
Methylation
Glutamine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[2]
Role of PTM	Potential impacts
Modified Residue	Glutamine	Modified Location	271
Related Enzyme	Methyltransferase N6AMT1 (N6AMT1)
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at ABCA2 Glutamine 271 has the potential to affect its expression or activity.
N-glycosylation
Asparagine	25 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	14
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 14 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	89
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 89 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	168
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 168 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	173
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 173 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	305
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 305 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	368
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 368 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	379
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 379 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	420
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 420 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	432
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 432 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	476
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 476 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	484
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 484 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	494
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 494 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	530
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 530 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	544
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 544 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	590
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 590 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	600
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 600 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	628
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 628 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1408
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1408 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1496
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1496 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1549
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1549 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1557
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1557 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1612
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1612 has the potential to affect its expression or activity.
PTM Phenomenon23	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1677
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1677 has the potential to affect its expression or activity.
PTM Phenomenon24	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1775
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 1775 has the potential to affect its expression or activity.
PTM Phenomenon25	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	2054
Experimental Method	Co-Immunoprecipitation
Detailed Description	N-linked Glycosylation at ABCA2 Asparagine 2054 has the potential to affect its expression or activity.
O-glycosylation
Serine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[4], [5]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1141
Experimental Method	Co-Immunoprecipitation
Detailed Description	O-linked Glycosylation at ABCA2 Serine 1141 has the potential to affect its expression or activity.
Oxidation
Cystine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[6]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	848
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCA2 Cystine 848 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[6]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	991
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at ABCA2 Cystine 991 has the potential to affect its expression or activity.
Phosphorylation
Asparagine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[7], [8]
Role of PTM	Potential impacts
Modified Residue	Asparagine	Modified Location	1358
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Asparagine 1358 has the potential to affect its expression or activity.
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[7], [8]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1362
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Cystine 1362 has the potential to affect its expression or activity.
Glutamicacid	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Glutamicacid	Modified Location	1250
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Glutamicacid 1250 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[9], [10]
Role of PTM	Potential impacts
Modified Residue	Glutamicacid	Modified Location	2413
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Glutamicacid 2413 has the potential to affect its expression or activity.
Glycine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[8]
Role of PTM	Potential impacts
Modified Residue	Glycine	Modified Location	1441
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Glycine 1441 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[8]
Role of PTM	Potential impacts
Modified Residue	Glycine	Modified Location	1582
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Glycine 1582 has the potential to affect its expression or activity.
Leucine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[11]
Role of PTM	Potential impacts
Modified Residue	Leucine	Modified Location	282
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Leucine 282 has the potential to affect its expression or activity.
Proline	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Proline	Modified Location	1590
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Proline 1590 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[8]
Role of PTM	Potential impacts
Modified Residue	Proline	Modified Location	1591
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Proline 1591 has the potential to affect its expression or activity.
Serine	60 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[12]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	50
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 50 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[11], [13]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	118
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 118 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	137
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 137 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA2			[11]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	255
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 255 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA2			[14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	280
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 280 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA2			[14]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	283
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 283 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCA2			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	958
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 958 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCA2			[16], [17]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1045
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1045 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCA2			[16], [18]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1047
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1047 has the potential to affect its expression or activity.
PTM Phenomenon10	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1076
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1076 has the potential to affect its expression or activity.
PTM Phenomenon11	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1076
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1076 has the potential to affect its expression or activity.
PTM Phenomenon12	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1078
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1078 has the potential to affect its expression or activity.
PTM Phenomenon13	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1078
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1078 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1093
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1093 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence ABCA2			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1113
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1113 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence ABCA2			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1118
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1118 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence ABCA2			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1124
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1124 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1132
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1132 has the potential to affect its expression or activity.
PTM Phenomenon19	Have the potential to influence ABCA2			[21], [22]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1237
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1237 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence ABCA2			[9], [23]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1238
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1238 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1247
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1247 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence ABCA2			[9]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1268
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1268 has the potential to affect its expression or activity.
PTM Phenomenon23	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1269
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1269 has the potential to affect its expression or activity.
PTM Phenomenon24	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1269
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1269 has the potential to affect its expression or activity.
PTM Phenomenon25	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1269
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1269 has the potential to affect its expression or activity.
PTM Phenomenon26	Have the potential to influence ABCA2			[21], [24]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1322
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1322 has the potential to affect its expression or activity.
PTM Phenomenon27	Have the potential to influence ABCA2			[23], [25]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1327
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1327 has the potential to affect its expression or activity.
PTM Phenomenon28	Have the potential to influence ABCA2			[23], [25]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1331
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1331 has the potential to affect its expression or activity.
PTM Phenomenon29	Have the potential to influence ABCA2			[24]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1338
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1338 has the potential to affect its expression or activity.
PTM Phenomenon30	Have the potential to influence ABCA2			[26]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1351
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1351 has the potential to affect its expression or activity.
PTM Phenomenon31	Have the potential to influence ABCA2			[27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1371
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1371 has the potential to affect its expression or activity.
PTM Phenomenon32	Have the potential to influence ABCA2			[27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1374
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1374 has the potential to affect its expression or activity.
PTM Phenomenon33	Have the potential to influence ABCA2			[27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1376
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1376 has the potential to affect its expression or activity.
PTM Phenomenon34	Have the potential to influence ABCA2			[27]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1377
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1377 has the potential to affect its expression or activity.
PTM Phenomenon35	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1382
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1382 has the potential to affect its expression or activity.
PTM Phenomenon36	Have the potential to influence ABCA2			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1410
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1410 has the potential to affect its expression or activity.
PTM Phenomenon37	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1530
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1530 has the potential to affect its expression or activity.
PTM Phenomenon38	Have the potential to influence ABCA2			[8], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1551
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1551 has the potential to affect its expression or activity.
PTM Phenomenon39	Have the potential to influence ABCA2			[8], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1559
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1559 has the potential to affect its expression or activity.
PTM Phenomenon40	Have the potential to influence ABCA2			[8], [15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1560
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1560 has the potential to affect its expression or activity.
PTM Phenomenon41	Have the potential to influence ABCA2			[15]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1563
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1563 has the potential to affect its expression or activity.
PTM Phenomenon42	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1586
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1586 has the potential to affect its expression or activity.
PTM Phenomenon43	Have the potential to influence ABCA2			[7], [8]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1594
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1594 has the potential to affect its expression or activity.
PTM Phenomenon44	Have the potential to influence ABCA2			[28]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1705
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1705 has the potential to affect its expression or activity.
PTM Phenomenon45	Have the potential to influence ABCA2			[29]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1738
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1738 has the potential to affect its expression or activity.
PTM Phenomenon46	Have the potential to influence ABCA2			[29]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1745
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1745 has the potential to affect its expression or activity.
PTM Phenomenon47	Have the potential to influence ABCA2			[30]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1981
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 1981 has the potential to affect its expression or activity.
PTM Phenomenon48	Have the potential to influence ABCA2			[31]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2035
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2035 has the potential to affect its expression or activity.
PTM Phenomenon49	Have the potential to influence ABCA2			[32]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2117
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2117 has the potential to affect its expression or activity.
PTM Phenomenon50	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2322
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2322 has the potential to affect its expression or activity.
PTM Phenomenon51	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2326
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2326 has the potential to affect its expression or activity.
PTM Phenomenon52	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2332
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2332 has the potential to affect its expression or activity.
PTM Phenomenon53	Have the potential to influence ABCA2			[33]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2381
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2381 has the potential to affect its expression or activity.
PTM Phenomenon54	Have the potential to influence ABCA2			[24], [34]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2419
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2419 has the potential to affect its expression or activity.
PTM Phenomenon55	Have the potential to influence ABCA2			[20]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2428
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2428 has the potential to affect its expression or activity.
PTM Phenomenon56	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2450
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2450 has the potential to affect its expression or activity.
PTM Phenomenon57	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2450
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2450 has the potential to affect its expression or activity.
PTM Phenomenon58	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2459
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2459 has the potential to affect its expression or activity.
PTM Phenomenon59	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2459
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2459 has the potential to affect its expression or activity.
PTM Phenomenon60	.			[19]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	2459
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Serine 2459 has the potential to affect its expression or activity.
Threonine	24 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[11], [35]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	251
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 251 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[36]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	422
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 422 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA2			[16], [37]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1049
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1049 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA2			[16], [38]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1057
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1057 has the potential to affect its expression or activity.
PTM Phenomenon5	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1080
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1080 has the potential to affect its expression or activity.
PTM Phenomenon6	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1080
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1080 has the potential to affect its expression or activity.
PTM Phenomenon7	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1088
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1088 has the potential to affect its expression or activity.
PTM Phenomenon8	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1088
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1088 has the potential to affect its expression or activity.
PTM Phenomenon9	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1088
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1088 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1219
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1219 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCA2			[8], [39]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1390
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1390 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1531
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1531 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence ABCA2			[8], [15]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1555
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1555 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCA2			[28]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1712
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1712 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence ABCA2			[29]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1741
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1741 has the potential to affect its expression or activity.
PTM Phenomenon16	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1743
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1743 has the potential to affect its expression or activity.
PTM Phenomenon17	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	1743
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 1743 has the potential to affect its expression or activity.
PTM Phenomenon18	Have the potential to influence ABCA2			[40]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2056
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2056 has the potential to affect its expression or activity.
PTM Phenomenon19	.			[19]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2087
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2087 has the potential to affect its expression or activity.
PTM Phenomenon20	Have the potential to influence ABCA2			[41]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2101
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2101 has the potential to affect its expression or activity.
PTM Phenomenon21	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2397
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2397 has the potential to affect its expression or activity.
PTM Phenomenon22	Have the potential to influence ABCA2			[23], [42]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2412
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2412 has the potential to affect its expression or activity.
PTM Phenomenon23	Have the potential to influence ABCA2			[43]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2431
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2431 has the potential to affect its expression or activity.
PTM Phenomenon24	Have the potential to influence ABCA2			[43], [44]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2433
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Threonine 2433 has the potential to affect its expression or activity.
Tyrosine	14 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[16], [45]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1051
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1051 has the potential to affect its expression or activity.
PTM Phenomenon2	.			[19]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1082
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1082 has the potential to affect its expression or activity.
PTM Phenomenon3	.			[19]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1082
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1082 has the potential to affect its expression or activity.
PTM Phenomenon4	.			[19]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1082
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1082 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA2			[7]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1216
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1216 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence ABCA2			[8], [39]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1389
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1389 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence ABCA2			[8]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1393
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1393 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCA2			[8], [39]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1396
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1396 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence ABCA2			[46], [47]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1694
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1694 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence ABCA2			[3]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1731
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1731 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence ABCA2			[29]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1736
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1736 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence ABCA2			[29]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	1742
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 1742 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence ABCA2			[46], [48]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	2178
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 2178 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence ABCA2			[46], [49]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	2186
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Tyrosine 2186 has the potential to affect its expression or activity.
Valine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[8]
Role of PTM	Potential impacts
Modified Residue	Valine	Modified Location	989
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 Valine 989 has the potential to affect its expression or activity.
Unclear Residue	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[8], [9]
Role of PTM	Potential impacts
Modified Location	2443
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at ABCA2 2443 has the potential to affect its expression or activity.
S-nitrosylation
Cystine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[50]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	966
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at ABCA2 Cystine 966 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[50]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	1362
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at ABCA2 Cystine 1362 has the potential to affect its expression or activity.
Ubiquitination
Arginine	4 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	1116
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Arginine 1116 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	1129
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Arginine 1129 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	1159
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Arginine 1159 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA2			[52]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	1223
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Arginine 1223 has the potential to affect its expression or activity.
Asparticacid	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[53]
Role of PTM	Potential impacts
Modified Residue	Asparticacid	Modified Location	1341
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Asparticacid 1341 has the potential to affect its expression or activity.
Glutamicacid	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[52]
Role of PTM	Potential impacts
Modified Residue	Glutamicacid	Modified Location	1337
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Glutamicacid 1337 has the potential to affect its expression or activity.
Glutamine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[54]
Role of PTM	Potential impacts
Modified Residue	Glutamine	Modified Location	1367
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Glutamine 1367 has the potential to affect its expression or activity.
Isoleucine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Isoleucine	Modified Location	1161
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Isoleucine 1161 has the potential to affect its expression or activity.
Leucine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Leucine	Modified Location	1131
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Leucine 1131 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Leucine	Modified Location	1146
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Leucine 1146 has the potential to affect its expression or activity.
Lysine	8 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1115
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1115 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1128
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1128 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence ABCA2			[51]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1130
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1130 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence ABCA2			[52]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1222
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1222 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence ABCA2			[52], [54]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1336
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1336 has the potential to affect its expression or activity.
PTM Phenomenon6	.			[19]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1735
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1735 has the potential to affect its expression or activity.
PTM Phenomenon7	.			[19]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	1735
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 1735 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence ABCA2			[51], [55]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	2025
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Lysine 2025 has the potential to affect its expression or activity.
Proline	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[52]
Role of PTM	Potential impacts
Modified Residue	Proline	Modified Location	2026
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Proline 2026 has the potential to affect its expression or activity.
Serine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[53]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	1371
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Serine 1371 has the potential to affect its expression or activity.
Threonine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence ABCA2			[56], [57]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2056
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at ABCA2 Threonine 2056 has the potential to affect its expression or activity.

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