Detail Information of Mutation-induced Spatial Variation
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0346 Transporter Info | ||||
| Gene Name | SLC39A5 | ||||
| Transporter Name | Zinc transporter ZIP5 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Mutation-induced Structural Variation (MSV) of This DT | |||||
| PDB ID | |||||
| Expression System | Escherichia coli; synthetic construct | ||||
| Method | X-ray | ||||
| Resolution | 2.75 Å | ||||
| Corresponding chain | A/B | ||||
| Mutation Site(s) | L52A; F53A; L56A; F60A; V64A; F68A | [1] | |||
| Structure Details | |||||
| Modeling Method | X-ray | ||||
| Publication year | 2023 | ||||
| PDB ID | Scanning Method | Resolution | Mutation Sites | Details | Ref |
| 7YF4 | X-ray | 2.75 Å | L52A; F53A; L56A; F60A; V64A; F68A | [1] | |
| Structure | |||||
| Expression System | Escherichia coli; synthetic construct | ||||
| Corresponding chain | A/B | ||||
| Sequence Length | 46-318 | Mutation | Yes | ||
| References | |||||
| 1 | Molecular basis for METTL9-mediated N1-histidine methylation. Cell Discov. 2023;9(1):38. | ||||
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