Crystal Structure of This DT
Crystallisation Method:EM
Corresponding Chain:A
Sequence Length:1-630
Detail: Struture Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0456 Transporter Info | ||||
| Gene Name | SLC6A4 | ||||
| Protein Name | Sodium-dependent serotonin transporter | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Slc6a4 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6VRH_A Sequence Length:630 Identity:92.54% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1661.111 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | High |
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| Ramachandran Plot |
Ramz Z Score:-0.44 ±0.32 Residues in Favored Region:614 Ramachandran favored:97.77% Number of Outliers:2 Ramachandran outliers:0.32% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.81 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Slc6a4 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6VRH_A Sequence Length:630 Identity:91.746% |
||||
| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1596.207 kcal/mol | |||
| Ramachandra Favored | Medium |
||||
| QMEANBrane Quality | High |
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| Ramachandran Plot |
Ramz Z Score:-0.55 ±0.32 Residues in Favored Region:608 Ramachandran favored:96.82% Number of Outliers:3 Ramachandran outliers:0.48% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.81 |
||||
| Click to Save Local Quality Plot in PNG Format | |||||
| Drosophila melanogaster (Fruit fly) | |||||
| Gene Name | SerT | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6VRH_A Sequence Length:568 Identity:55.245% |
||||
| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1486.333 kcal/mol | |||
| Ramachandra Favored | Medium |
||||
| QMEANBrane Quality | High |
||||
| Ramachandran Plot |
Ramz Z Score:-0.74 ±0.33 Residues in Favored Region:548 Ramachandran favored:96.82% Number of Outliers:1 Ramachandran outliers:0.18% |
||||
| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.81 |
||||
| Click to Save Local Quality Plot in PNG Format | |||||
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